Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition - Wikidata - wikimedia - TriplyDB

Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition

Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition

http://www.wikidata.org/entity/Q33762700

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P53 mutations in colorectal cancer - molecular pathogenesis and pharmacological reactivation Activating transcription factor 3 promotes malignance of lung cancer cells in vitro High-amylose resistant starch increases hormones and improves structure and function of the gastrointestinal tract: a microarray study.Systems analysis of ATF3 in stress response and cancer reveals opposing effects on pro-apoptotic genes in p53 pathway.Activating transcription factor 3-mediated chemo-intervention with cancer chemokines in a noncanonical pathway under endoplasmic reticulum stress Small molecule inhibition of cytoskeletal dynamics in melanoma tumors results in altered transcriptional expression patterns of key genes involved in tumor initiation and progression.Loss of ATF3 promotes Akt activation and prostate cancer development in a Pten knockout mouse model The common stress responsive transcription factor ATF3 binds genomic sites enriched with p300 and H3K27ac for transcriptional regulation.Site-specific gene expression profiling as a novel strategy for unravelling keloid disease pathobiology.STAT5b as molecular target in pancreatic cancer--inhibition of tumor growth, angiogenesis, and metastases.Detection of gene communities in multi-networks reveals cancer drivers.In Vitro Anticancer Activity of Phlorofucofuroeckol A via Upregulation of Activating Transcription Factor 3 against Human Colorectal Cancer Cells Upregulation of ATF-3 is correlated with prognosis and proliferation of laryngeal cancer by regulating Cyclin D1 expression.ASBEL-TCF3 complex is required for the tumorigenicity of colorectal cancer cells.Expression and clinical significance of activating transcription factor 3 in human breast cancer.The activating transcription factor 3 protein suppresses the oncogenic function of mutant p53 proteins.Ribosomal protein L34 promotes the proliferation, invasion and metastasis of pancreatic cancer cells.ATF3 and extracellular matrix-related genes associated with the process of chronic obstructive pulmonary.Drug-Induced HSP90 Inhibition Alleviates Pain in Monoarthritic Rats and Alters the Expression of New Putative Pain Players at the DRG.The catalytic topoisomerase II inhibitor dexrazoxane induces DNA breaks, ATF3 and the DNA damage response in cancer cells.Activating transcription factor 3 promotes colon cancer metastasis.Expression of core 3 synthase in human pancreatic cancer cells suppresses tumor growth and metastasis.3,3'-diindolylmethane induces activating transcription factor 3 (ATF3) via ATF4 in human colorectal cancer cells.An analog of withaferin A activates the MAPK and glutathione "stress" pathways and inhibits pancreatic cancer cell proliferation.Key role of ATF3 in p53-dependent DR5 induction upon DNA damage of human colon cancer cells.Canonical NF-κB signaling in hepatocytes acts as a tumor-suppressor in hepatitis B virus surface antigen-driven hepatocellular carcinoma by controlling the unfolded protein response.Overexpression of the transcription factor ATF3 with a regulatory molecular signature associates with the pathogenic development of colorectal cancer.Enhanced Therapeutic Treatment of Colorectal Cancer Using Surface-Modified Nanoporous Acupuncture Needles Atf3 deficiency promotes genome instability and spontaneous tumorigenesis in mice.Glucose-regulated protein 78 mediates the therapeutic efficacy of 17-DMAG in colon cancer cells.Neuropilin-1 promotes the oncogenic Tenascin-C/integrin β3 pathway and modulates chemoresistance in breast cancer cells.Serum and Adipose Tissue mRNA Levels of ATF3 and FNDC5/Irisin in Colorectal Cancer Patients With or Without Obesity

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Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition

http://www.wikidata.org/entity/Q33762700

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

@zh-tw

2010年论文

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name

Activating transcription facto ...... protein 90 (Hsp90) inhibition

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Activating transcription facto ...... protein 90 (Hsp90) inhibition

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Activating transcription facto ...... protein 90 (Hsp90) inhibition

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Activating transcription facto ...... protein 90 (Hsp90) inhibition

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Activating transcription facto ...... protein 90 (Hsp90) inhibition

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Akira Mori

http://www.w3.org/2001/XMLSchema#string

Christian Moser

http://www.w3.org/2001/XMLSchema#string

Christina Hackl

http://www.w3.org/2001/XMLSchema#string

Claus Hellerbrand

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Edward K Geissler

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Hans J Schlitt

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Oliver Stoeltzing

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Stefan Fichtner-Feigl

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Sven A Lang

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Wolfgang Dietmeier

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P2860

A splice variant of stress response gene ATF3 counteracts NF-kappaB-dependent anti-apoptosis through inhibiting recruitment of CREB-binding protein/p300 coactivator

Microsatellite instability in tumor and nonneoplastic colorectal cells from hereditary non-polyposis colorectal cancer and sporadic high microsatellite-instable tumor patients.

The tumor metastasis suppressor gene Drg-1 down-regulates the expression of activating transcription factor 3 in prostate cancer.

A biochemical rationale for the anticancer effects of Hsp90 inhibitors: slow, tight binding inhibition by geldanamycin and its analogues.

Chaperoning signaling pathways: molecular chaperones as stress-sensing 'heat shock' proteins.

Heat shock protein 90 as a molecular target for cancer therapeutics.

Heat shock protein 90.

Targeting multiple signal transduction pathways through inhibition of Hsp90.

Regulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by an insulin-like growth factor-I receptor autocrine loop in human pancreatic cancer

Altered Hsp90 function in cancer: a unique therapeutic opportunity.

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1471-2407-10-668

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1031631593

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21129190

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3003660

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