about
The chemokine receptor CCR1 is constitutively active, which leads to G protein-independent, β-arrestin-mediated internalizationUnderstanding molecular recognition by G protein βγ subunits on the path to pharmacological targetingExpression analysis of G Protein-Coupled Receptors in mouse macrophagesThe human olfactory receptor repertoireGenome wide survey of G protein-coupled receptors in Tetraodon nigroviridis.Structure modeling of all identified G protein-coupled receptors in the human genomeNovel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regionsBiophysical methods to study ligand-receptor interactions of neuropeptide YIn silico modeling of human α2C-adrenoreceptor interaction with filamin-2High-level production, solubilization and purification of synthetic human GPCR chemokine receptors CCR5, CCR3, CXCR4 and CX3CR1Novel RNAi-mediated approach to G protein-coupled receptor deorphanization: proof of principle and characterization of a planarian 5-HT receptorBPROMPT: A consensus server for membrane protein predictionA combined ligand-based and target-based drug design approach for G-protein coupled receptors: application to salvinorin A, a selective kappa opioid receptor agonist.Evidence for a bacterial lipopolysaccharide-recognizing G-protein-coupled receptor in the bacterial engulfment by Entamoeba histolytica.The repertoire of G protein-coupled receptors in the sea squirt Ciona intestinalis.Eleven new putative aminergic G-protein coupled receptors from Amphioxus (Branchiostoma floridae): identification, sequence analysis and phylogenetic relationship.GPCRTree: online hierarchical classification of GPCR function.Recent advances and future directions for the pharmacogenetic basis of anti-VEGF treatment response in neovascular age-related macular degenerationMolecular mechanisms deployed by virally encoded G protein-coupled receptors in human diseases.Beyond desensitization: physiological relevance of arrestin-dependent signaling.Chaperoning G protein-coupled receptors: from cell biology to therapeuticsThe parathyroid hormone, its fragments and analogues--potent bone-builders for treating osteoporosis.The repertoire of G protein-coupled receptors in the human parasite Schistosoma mansoni and the model organism Schmidtea mediterraneaGeneration of full-length cDNAs for eight putative GPCnR from the cattle tick, R. microplus using a targeted degenerate PCR and sequencing strategyPolar residues drive association of polyleucine transmembrane helicesExpression and purification of functional human mu opioid receptor from E.coli.Homology modeling of opioid receptor-ligand complexes using experimental constraintsRegulators of G protein signalling: potential targets for treatment of allergic inflammatory diseases such as asthma.The significance of G protein-coupled receptor crystallography for drug discovery.Conformational changes of G protein-coupled receptors during their activation by agonist binding.GRK2 and β-arrestins in cardiovascular disease: Something old, something new.NMR studies in dodecylphosphocholine of a fragment containing the seventh transmembrane helix of a G-protein-coupled receptor from Saccharomyces cerevisiae.Role of extracellular charged amino acids in the yeast alpha-factor receptor.Viral hijacking of G-protein-coupled-receptor signalling networks.High-level expression in Saccharomyces cerevisiae enables isolation and spectroscopic characterization of functional human adenosine A2a receptorExon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma.Physiological Roles of GPR10 and PrRP SignalingRecognition of neurohormones of the NPY family by their receptors.Proteomic applications of automated GPCR classification.When a G protein-coupled receptor does not couple to a G protein.
P2860
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P2860
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Modelling G-protein-coupled receptors for drug design.
@ast
Modelling G-protein-coupled receptors for drug design.
@en
type
label
Modelling G-protein-coupled receptors for drug design.
@ast
Modelling G-protein-coupled receptors for drug design.
@en
prefLabel
Modelling G-protein-coupled receptors for drug design.
@ast
Modelling G-protein-coupled receptors for drug design.
@en
P1476
Modelling G-protein-coupled receptors for drug design.
@en
P2093
D R Flower
P304
P356
10.1016/S0304-4157(99)00006-4
P407
P577
1999-11-01T00:00:00Z