Explaining oscillations and variability in the p53-Mdm2 system
about
Feedback between p21 and reactive oxygen production is necessary for cell senescenceCancer systems biology: a network modeling perspectiveExperimental and computational analysis of polyglutamine-mediated cytotoxicityBioModels: Content, Features, Functionality, and UseModeling the role of p53 pulses in DNA damage- induced cell death decision.Modelling the response of FOXO transcription factors to multiple post-translational modifications made by ageing-related signalling pathwaysStress-specific response of the p53-Mdm2 feedback loopGlobal analysis of phase locking in gene expression during cell cycle: the potential in network modeling.The ups and downs of p53: understanding protein dynamics in single cellsEvaluation of the collaborative network of highly correlating skin proteins and its change following treatment with glucocorticoidsNoise amplification in human tumor suppression following gamma irradiation.Fibroid explants reveal a higher sensitivity against MDM2-inhibitor nutlin-3 than matching myometrium.The dynamics of stress p53-Mdm2 network regulated by p300 and HDAC1.An evolutionary firefly algorithm for the estimation of nonlinear biological model parametersThe role of mRNA decay in p53-induced gene expressionBifurcation in Cell Cycle Dynamics Regulated by p53MiR-192-Mediated Positive Feedback Loop Controls the Robustness of Stress-Induced p53 Oscillations in Breast Cancer CellsA novel mathematical model of ATM/p53/NF- κB pathways points to the importance of the DDR switch-off mechanismsModeling drug- and chemical-induced hepatotoxicity with systems biology approaches.Non-random aneuploidy specifies subgroups of pilocytic astrocytoma and correlates with older age.Notch4-dependent antagonism of canonical TGF-β1 signaling defines unique temporal fluctuations of SMAD3 activity in sheared proximal tubular epithelial cells.MDM2 phenotypic and genotypic profiling, respective to TP53 genetic status, in diffuse large B-cell lymphoma patients treated with rituximab-CHOP immunochemotherapy: a report from the International DLBCL Rituximab-CHOP Consortium Program.Systems biology of ageing and longevity.Multidimensional control of cell structural robustness.Modelling the molecular mechanisms of aging.Computational modelling folate metabolism and DNA methylation: implications for understanding health and ageing.Attractor landscape analysis reveals feedback loops in the p53 network that control the cellular response to DNA damage.Harmonic oscillations in homeostatic controllers: Dynamics of the p53 regulatory system.GSK3 and p53 - is there a link in Alzheimer's disease?A unifying hypothesis for familial and sporadic Alzheimer's disease.Dynamical states, possibilities and propagation of stress signal.Significance of p53 dynamics in regulating apoptosis in response to ionizing radiation, and polypharmacological strategiesThe Ink4a/Arf locus operates as a regulator of the circadian clock modulating RAS activity.Computer simulation models as a tool to investigate the role of microRNAs in osteoarthritis.Comparison of cellular oscillations driven by noise or deterministic mechanisms under cell-size scaling.Control of apoptosis by SMAR1.Synchronization in stress p53 network.A plausible model for bimodal p53 switch in DNA damage response.Switching p53 states by calcium: dynamics and interaction of stress systems.A Digitally Programmable Cytomorphic Chip for Simulation of Arbitrary Biochemical Reaction Networks.
P2860
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P2860
Explaining oscillations and variability in the p53-Mdm2 system
description
2008 nî lūn-bûn
@nan
2008 թուականին հրատարակուած գիտական յօդուած
@hyw
2008 թվականին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
Explaining oscillations and variability in the p53-Mdm2 system
@ast
Explaining oscillations and variability in the p53-Mdm2 system
@en
Explaining oscillations and variability in the p53-Mdm2 system
@en-gb
Explaining oscillations and variability in the p53-Mdm2 system
@nl
type
label
Explaining oscillations and variability in the p53-Mdm2 system
@ast
Explaining oscillations and variability in the p53-Mdm2 system
@en
Explaining oscillations and variability in the p53-Mdm2 system
@en-gb
Explaining oscillations and variability in the p53-Mdm2 system
@nl
prefLabel
Explaining oscillations and variability in the p53-Mdm2 system
@ast
Explaining oscillations and variability in the p53-Mdm2 system
@en
Explaining oscillations and variability in the p53-Mdm2 system
@en-gb
Explaining oscillations and variability in the p53-Mdm2 system
@nl
P2860
P356
P1433
P1476
Explaining oscillations and variability in the p53-Mdm2 system
@en
P2860
P2888
P356
10.1186/1752-0509-2-75
P407
P577
2008-01-01T00:00:00Z
P5875
P6179
1045225076