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Engineering mouse models with myelodysplastic syndrome human candidate genes; how relevant are they?Revisiting the case for genetically engineered mouse models in human myelodysplastic syndrome researchSplicing factor 3b subunit 1 (Sf3b1) haploinsufficient mice display features of low risk Myelodysplastic syndromes with ring sideroblasts.Alkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations with Leukemia Stem Cell ActivityMice heterozygous for CREB binding protein are hypersensitive to γ-radiation and invariably develop myelodysplastic/myeloproliferative neoplasmGrowth factor independence 1 (Gfi1) regulates cell-fate decision of a bipotential granulocytic-monocytic precursor defined by expression of Gfi1 and CD48.Loss of the tumor suppressor BAP1 causes myeloid transformation.The Corepressor Rcor1 Is Essential for Normal Myeloerythroid Lineage Differentiation.Physiologic Expression of Sf3b1(K700E) Causes Impaired Erythropoiesis, Aberrant Splicing, and Sensitivity to Therapeutic Spliceosome Modulation.Epigenetically Aberrant Stroma in MDS Propagates Disease via Wnt/β-Catenin Activation.Brief report: Loss of p15Ink4b accelerates development of myeloid neoplasms in Nup98-HoxD13 transgenic mice.
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Mouse models of myelodysplastic syndromes.
@ast
Mouse models of myelodysplastic syndromes.
@en
type
label
Mouse models of myelodysplastic syndromes.
@ast
Mouse models of myelodysplastic syndromes.
@en
prefLabel
Mouse models of myelodysplastic syndromes.
@ast
Mouse models of myelodysplastic syndromes.
@en
P2860
P1476
Mouse models of myelodysplastic syndromes.
@en
P2093
Peter D Aplan
Sarah H Beachy
P2860
P304
P356
10.1016/J.HOC.2010.02.002
P577
2010-04-01T00:00:00Z