Genetic dissection of azole resistance mechanisms in Candida albicans and their validation in a mouse model of disseminated infection
about
The potential impact of antifungal drug resistance mechanisms on the host immune response to CandidaAmplification of TLO Mediator Subunit Genes Facilitate Filamentous Growth in Candida SppPho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasisMultilaboratory study of epidemiological cutoff values for detection of resistance in eight Candida species to fluconazole, posaconazole, and voriconazole.Elevated catalase expression in a fungal pathogen is a double-edged sword of iron.CO(2) acts as a signalling molecule in populations of the fungal pathogen Candida albicansThioredoxin regulates multiple hydrogen peroxide-induced signaling pathways in Candida albicans.Regulatory circuitry governing fungal development, drug resistance, and disease.Differential regulation of kidney and spleen cytokine responses in mice challenged with pathology-standardized doses of Candida albicans mannosylation mutantsActivation of the heat shock transcription factor Hsf1 is essential for the full virulence of the fungal pathogen Candida albicans.The Mnn2 mannosyltransferase family modulates mannoprotein fibril length, immune recognition and virulence of Candida albicansMolecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicansMultidrug-resistant transporter mdr1p-mediated uptake of a novel antifungal compoundIbuprofen-mediated reversal of fluconazole resistance in clinical isolates of CandidaMAPKKK-independent regulation of the Hog1 stress-activated protein kinase in Candida albicans.The differential view of genotype-phenotype relationships.Contribution of Fdh3 and Glr1 to Glutathione Redox State, Stress Adaptation and Virulence in Candida albicansElevated cell wall chitin in Candida albicans confers echinocandin resistance in vivo.Ibuprofen potentiates the in vivo antifungal activity of fluconazole against Candida albicans murine infectionA Novel Small Molecule Inhibitor of Candida albicans Biofilm Formation, Filamentation and Virulence with Low Potential for the Development of Resistance.The Rewiring of Ubiquitination Targets in a Pathogenic Yeast Promotes Metabolic Flexibility, Host Colonization and Virulence.Resistance Surveillance in Candida albicans: A Five-Year Antifungal Susceptibility Evaluation in a Brazilian University Hospital.Progress in antifungal susceptibility testing of Candida spp. by use of Clinical and Laboratory Standards Institute broth microdilution methods, 2010 to 2012Blocking two-component signalling enhances Candida albicans virulence and reveals adaptive mechanisms that counteract sustained SAPK activationHost carbon sources modulate cell wall architecture, drug resistance and virulence in a fungal pathogenActivity of Isavuconazole and Other Azoles against Candida Clinical Isolates and Yeast Model Systems with Known Azole Resistance Mechanisms.Milbemycins: more than efflux inhibitors for fungal pathogensCandida tropicalis antifungal cross-resistance is related to different azole target (Erg11p) modifications.Fluconazole assists berberine to kill fluconazole-resistant Candida albicans.Antifungal agents commonly used in the superficial and mucosal candidiasis treatment: mode of action and resistance developmentYbp1 and Gpx3 signaling in Candida albicans govern hydrogen peroxide-induced oxidation of the Cap1 transcription factor and macrophage escape.Novel antifungal drug discovery based on targeting pathways regulating the fungus-conserved Upc2 transcription factorAcquired antifungal drug resistance in Aspergillus fumigatus: epidemiology and detection.The contribution of mouse models to our understanding of systemic candidiasis.Mechanisms of Antifungal Drug Resistance.Multiple mechanisms contribute to the development of clinically significant azole resistance in Aspergillus fumigatus.The fungal resistome: a risk and an opportunity for the development of novel antifungal therapies.Fluconazole resistance in Candida species: a current perspective.Antifungal resistance and new strategies to control fungal infections.Terbinafine Resistance of Trichophyton Clinical Isolates Caused by Specific Point Mutations in the Squalene Epoxidase Gene.
P2860
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P2860
Genetic dissection of azole resistance mechanisms in Candida albicans and their validation in a mouse model of disseminated infection
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Genetic dissection of azole re ...... odel of disseminated infection
@ast
Genetic dissection of azole re ...... odel of disseminated infection
@en
type
label
Genetic dissection of azole re ...... odel of disseminated infection
@ast
Genetic dissection of azole re ...... odel of disseminated infection
@en
prefLabel
Genetic dissection of azole re ...... odel of disseminated infection
@ast
Genetic dissection of azole re ...... odel of disseminated infection
@en
P2093
P2860
P50
P356
P1476
Genetic dissection of azole re ...... odel of disseminated infection
@en
P2093
Frank C Odds
Françoise Ischer
Mette D Jacobsen
P2860
P304
P356
10.1128/AAC.01645-09
P407
P577
2010-01-19T00:00:00Z