Inactivation of sterol Delta5,6-desaturase attenuates virulence in Candida albicans
about
Evolution of pathogenicity and sexual reproduction in eight Candida genomesEmerging Threats in Antifungal-Resistant Fungal PathogensThe potential impact of antifungal drug resistance mechanisms on the host immune response to CandidaFitness trade-offs restrict the evolution of resistance to amphotericin BAntifungal Therapy: New Advances in the Understanding and Treatment of MycosisGenetic dissection of azole resistance mechanisms in Candida albicans and their validation in a mouse model of disseminated infectionA clinical isolate of Candida albicans with mutations in ERG11 (encoding sterol 14alpha-demethylase) and ERG5 (encoding C22 desaturase) is cross resistant to azoles and amphotericin B.Azole resistance by loss of function of the sterol Δ⁵,⁶-desaturase gene (ERG3) in Candida albicans does not necessarily decrease virulenceIdentification and characterization of four azole-resistant erg3 mutants of Candida albicans.Fluconazole treatment is effective against a Candida albicans erg3/erg3 mutant in vivo despite in vitro resistance.Pathway analysis of Candida albicans survival and virulence determinants in a murine infection model.Upregulation of the ERG11 gene in Candida krusei by azolesTranscription factor ADS-4 regulates adaptive responses and resistance to antifungal azole stressImpact of antifungal prophylaxis on colonization and azole susceptibility of Candida species.Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species.Detection of species diversity in oral candida colonization and anti-fungal susceptibility among non-oral habit adult diabetic patients.Attenuation of Candida albicans virulence with focus on disruption of its vacuole functionsMedically important fungi respond to azole drugs: an update.The development of fluconazole resistance in Candida albicans - an example of microevolution of a fungal pathogen.Fluconazole resistance in Candida species: a current perspective.Design, synthesis, and biological evaluation of 1-[(biarylmethyl)methylamino]-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as potent antifungal agents: new insights into structure-activity relationships.Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis.Next-generation sequencing offers new insights into the resistance of Candida spp. to echinocandins and azoles.Design, synthesis, and in vitro antifungal activity of 1-[(4-substituted-benzyl)methylamino]-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ols.Loss of Upc2p-Inducible ERG3 Transcription Is Sufficient To Confer Niche-Specific Azole Resistance without Compromising Candida albicans Pathogenicity.Candida albicans gains azole resistance by altering sphingolipid composition
P2860
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P2860
Inactivation of sterol Delta5,6-desaturase attenuates virulence in Candida albicans
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Inactivation of sterol Delta5,6-desaturase attenuates virulence in Candida albicans
@ast
Inactivation of sterol Delta5,6-desaturase attenuates virulence in Candida albicans
@en
type
label
Inactivation of sterol Delta5,6-desaturase attenuates virulence in Candida albicans
@ast
Inactivation of sterol Delta5,6-desaturase attenuates virulence in Candida albicans
@en
prefLabel
Inactivation of sterol Delta5,6-desaturase attenuates virulence in Candida albicans
@ast
Inactivation of sterol Delta5,6-desaturase attenuates virulence in Candida albicans
@en
P2093
P2860
P1476
Inactivation of sterol Delta5,6-desaturase attenuates virulence in Candida albicans
@en
P2093
Andrew S Chau
Anthony Cacciapuoti
Maya Gurnani
Michel Laverdiere
Paul M McNicholas
Robyn Hawkinson
P2860
P304
P356
10.1128/AAC.49.9.3646-3651.2005
P407
P577
2005-09-01T00:00:00Z