A genetically defined mouse ovarian carcinoma model for the molecular characterization of pathway-targeted therapy and tumor resistance.
about
The DNA damage pathway regulates innate immune system ligands of the NKG2D receptorDeregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimusHOXB13 promotes ovarian cancer progressionExpression of the Carboxy-Terminal Portion of MUC16/CA125 Induces Transformation and Tumor InvasionLoss of PTEN is not associated with poor survival in newly diagnosed glioblastoma patients of the temozolomide era.Metformin downregulates the insulin/IGF-I signaling pathway and inhibits different uterine serous carcinoma (USC) cells proliferation and migration in p53-dependent or -independent mannersExploring the gain of function contribution of AKT to mammary tumorigenesis in mouse models.Xenograft and Transgenic Mouse Models of Epithelial Ovarian Cancer and Non Invasive Imaging Modalities to Monitor Ovarian Tumor Growth In situ -Applications in Evaluating Novel Therapeutic Agents.BRCA1-associated epigenetic regulation of p73 mediates an effector pathway for chemosensitivity in ovarian carcinoma.The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models.Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells.Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism.Aberrant over-expression of COX-1 intersects multiple pro-tumorigenic pathways in high-grade serous ovarian cancerA mouse model for the molecular characterization of brca1-associated ovarian carcinomaMinireview: animal models and mechanisms of ovarian cancer development.K-Ras mutation-mediated IGF-1-induced feedback ERK activation contributes to the rapalog resistance in pancreatic ductal adenocarcinomas.Rethinking ovarian cancer: recommendations for improving outcomes.Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivoModeling resistance to pathway-targeted therapy in ovarian cancerAlternative signaling pathways: when, where and why?Tumorigenesis and peritoneal colonization from fallopian tube epithelium.The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescence.Identification of FGFR4 as a potential therapeutic target for advanced-stage, high-grade serous ovarian cancerPTEN, more than the AKT pathway.Targeting the IKKβ/mTOR/VEGF signaling pathway as a potential therapeutic strategy for obesity-related breast cancer.Radiation-induced EGFR-signaling and control of DNA-damage repair.Models of ovarian cancer metastasis: Murine modelsRapamycin by itself and additively in combination with carboplatin inhibits the growth of ovarian cancer cellsEpithelial ovarian cancer experimental models.Critical review of preclinical approaches to evaluate the potential of immunosuppressive drugs to influence human neoplasia.Exploiting p70 S6 kinase as a target for ovarian cancer.Molecular Targeting of Growth Factor Receptor Signaling in Radiation Oncology.Identification of LMX1B as a novel oncogene in human ovarian cancer.Leukemias induced by altered TRK-signaling are sensitive to mTOR inhibitors in preclinical models.Xenograft and transgenic mouse models of epithelial ovarian cancer and non-invasive imaging modalities to monitor ovarian tumor growth in situ: applications in evaluating novel therapeutic agents.AKT induces senescence in primary esophageal epithelial cells but is permissive for differentiation as revealed in organotypic culture.MicroRNA-327 regulates cardiac hypertrophy and fibrosis induced by pressure overload.Genetically engineered mouse models of ovarian cancer and their utility in drug discovery.A polymorphism at miRNA-122-binding site in the IL-1α 3'UTR is associated with risk of epithelial ovarian cancer.
P2860
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P2860
A genetically defined mouse ovarian carcinoma model for the molecular characterization of pathway-targeted therapy and tumor resistance.
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
A genetically defined mouse ov ...... therapy and tumor resistance.
@ast
A genetically defined mouse ov ...... therapy and tumor resistance.
@en
type
label
A genetically defined mouse ov ...... therapy and tumor resistance.
@ast
A genetically defined mouse ov ...... therapy and tumor resistance.
@en
prefLabel
A genetically defined mouse ov ...... therapy and tumor resistance.
@ast
A genetically defined mouse ov ...... therapy and tumor resistance.
@en
P2860
P356
P1476
A genetically defined mouse ov ...... therapy and tumor resistance.
@en
P2093
Deyin Xing
Sandra Orsulic
P2860
P304
P356
10.1073/PNAS.0502256102
P407
P577
2005-04-28T00:00:00Z