AKT induces senescence in primary esophageal epithelial cells but is permissive for differentiation as revealed in organotypic culture.
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Bridging scales in cancer progression: mapping genotype to phenotype using neural networksImbalance of desmoplastic stromal cell numbers drives aggressive cancer processes.TLR3-mediated NF-{kappa}B signaling in human esophageal epithelial cells.Pro-oncogenic and anti-oncogenic pathways: opportunities and challenges of cancer therapy.Isolation and characterization of mouse and human esophageal epithelial cells in 3D organotypic culture.Exploiting tumor cell senescence in anticancer therapyPIK3CA-mediated PI3-kinase signalling is essential for HPV-induced transformation in vitroActivation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis.The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiationSOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis.LRRC31 is induced by IL-13 and regulates kallikrein expression and barrier function in the esophageal epithelium.ErbB receptors in the biology and pathology of the aerodigestive tractImpact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas.A PTEN inhibitor displays preclinical activity against hepatocarcinoma cellsIn vitro three-dimensional tumor microenvironment models for anticancer drug discovery.Disruption of prostate epithelial differentiation pathways and prostate cancer development.JARID1B Enables Transit between Distinct States of the Stem-like Cell Population in Oral CancersDesmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic esophagitis.Epithelial cell senescence: an adaptive response to pre-carcinogenic stresses?NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network.Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factorsCellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities.Identification and genetic manipulation of human and mouse oesophageal stem cells.Esophageal 3D Culture Systems as Modeling Tools in Esophageal Epithelial Pathobiology and Personalized Medicine.Inhibition of heat shock protein 90 suppresses squamous carcinogenic progression in a mouse model of esophageal cancer.
P2860
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P2860
AKT induces senescence in primary esophageal epithelial cells but is permissive for differentiation as revealed in organotypic culture.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
AKT induces senescence in prim ...... vealed in organotypic culture.
@en
type
label
AKT induces senescence in prim ...... vealed in organotypic culture.
@en
prefLabel
AKT induces senescence in prim ...... vealed in organotypic culture.
@en
P2093
P2860
P356
P1433
P1476
AKT induces senescence in prim ...... evealed in organotypic culture
@en
P2093
A K Rustgi
A Klein-Szanto
H Nakagawa
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210025
P407
P577
2006-10-09T00:00:00Z
P5875
P6179
1050330821