Epigenetic regulation of DACT2, a key component of the Wnt signalling pathway in human lung cancer.
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Wnt signaling pathway in non-small cell lung cancerPrognostic significance of the methylation of Wnt pathway antagonists-CXXC4, DACT2, and the inhibitors of sonic hedgehog signaling-ZIC1, ZIC4, and HHIP in head and neck squamous cell carcinomas.SOX17 methylation inhibits its antagonism of Wnt signaling pathway in lung cancer.Methylation of DACT2 promotes breast cancer development by activating Wnt signalingSecreted frizzled‑related protein 2 is epigenetically silenced and functions as a tumor suppressor in oral squamous cell carcinoma.Methylation of DACT2 promotes papillary thyroid cancer metastasis by activating Wnt signalingDACT2 is frequently methylated in human gastric cancer and methylation of DACT2 activated Wnt signaling.Methylation of CHFR sensitizes esophageal squamous cell cancer to docetaxel and paclitaxelEpigenetic silencing BCL6B induced colorectal cancer proliferation and metastasis by inhibiting P53 signaling.RASSF10 suppresses colorectal cancer growth by activating P53 signaling and sensitizes colorectal cancer cell to docetaxel.Epigenetic silencing of BCL6B inactivates p53 signaling and causes human hepatocellular carcinoma cell resist to 5-FU.TMEM196 acts as a novel functional tumour suppressor inactivated by DNA methylation and is a potential prognostic biomarker in lung cancer.Silencing NKD2 by promoter region hypermethylation promotes gastric cancer invasion and metastasis by up-regulating SOX18 in human gastric cancerDACT2 is a functional tumor suppressor through inhibiting Wnt/β-catenin pathway and associated with poor survival in colon cancer.SOX17 increases the cisplatin sensitivity of an endometrial cancer cell lineEpigenetic regulation of the Wnt signaling inhibitor DACT2 in human hepatocellular carcinoma.Methylation of DACT2 accelerates esophageal cancer development by activating Wnt signalingLHX6 acts as a novel potential tumour suppressor with epigenetic inactivation in lung cancerAberrant methylation of DACT1 and DACT2 are associated with tumor progression and poor prognosis in esophageal squamous cell carcinoma.DACT2 silencing by promoter CpG methylation disrupts its regulation of epithelial-to-mesenchymal transition and cytoskeleton reorganization in breast cancer cells.Upregulation of DACT2 suppresses proliferation and enhances apoptosis of glioma cell via inactivation of YAP signaling pathwayEpigenetic changes and functional study of HOXA11 in human gastric cancer.Clinicopathological significance of WIF1 hypermethylation in NSCLC, a meta-analysis and literature review.Epigenetic regulation of ANKRD18B in lung cancer.Methylation of TMEM176A is an independent prognostic marker and is involved in human colorectal cancer development.Ski regulates Smads and TAZ signaling to suppress lung cancer progression.Methylation of DACT2 contributes to the progression of breast cancer through activating WNT signaling pathway.Protein tyrosine phosphatases receptor type D is a potential tumour suppressor gene inactivated by deoxyribonucleic acid methylation in paediatric acute myeloid leukaemia.Prognostic and clinicopathological value of p16 protein aberrant expression in colorectal cancer: A PRISMA-compliant Meta-analysis.The new 6q27 tumor suppressor DACT2, frequently silenced by CpG methylation, sensitizes nasopharyngeal cancer cells to paclitaxel and 5-FU toxicity via β-catenin/Cdc25c signaling and G2/M arrest
P2860
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P2860
Epigenetic regulation of DACT2, a key component of the Wnt signalling pathway in human lung cancer.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Epigenetic regulation of DACT2 ...... pathway in human lung cancer.
@ast
Epigenetic regulation of DACT2 ...... pathway in human lung cancer.
@en
type
label
Epigenetic regulation of DACT2 ...... pathway in human lung cancer.
@ast
Epigenetic regulation of DACT2 ...... pathway in human lung cancer.
@en
prefLabel
Epigenetic regulation of DACT2 ...... pathway in human lung cancer.
@ast
Epigenetic regulation of DACT2 ...... pathway in human lung cancer.
@en
P2093
P2860
P356
P1476
Epigenetic regulation of DACT2 ...... pathway in human lung cancer.
@en
P2093
James G Herman
Malcolm V Brock
Mingzhou Guo
Qimin Zhan
Yunsheng Yang
P2860
P304
P356
10.1002/PATH.4073
P577
2013-06-01T00:00:00Z