Efficient repair of abasic sites in DNA by mitochondrial enzymes.
about
The human DNA ligase III gene encodes nuclear and mitochondrial proteinsHuman DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediatesMitochondrial DNA ligase III function is independent of Xrcc1.DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repairAntisense-mediated decrease in DNA ligase III expression results in reduced mitochondrial DNA integrityEarly steps in the DNA base excision/single-strand interruption repair pathway in mammalian cellsInactivation of Saccharomyces cerevisiae OGG1 DNA repair gene leads to an increased frequency of mitochondrial mutants.Pir1p mediates translocation of the yeast Apn1p endonuclease into the mitochondria to maintain genomic stabilityMgm101p is a novel component of the mitochondrial nucleoid that binds DNA and is required for the repair of oxidatively damaged mitochondrial DNAExpression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAsMitochondria-to-nucleus stress signaling induces phenotypic changes, tumor progression and cell invasionRat MYH, a glycosylase for repair of oxidatively damaged DNA, has brain-specific isoforms that localize to neuronal mitochondriaIdentification of 5'-deoxyribose phosphate lyase activity in human DNA polymerase gamma and its role in mitochondrial base excision repair in vitro.Human APE2 protein is mostly localized in the nuclei and to some extent in the mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigenRepair of mtDNA in vertebrates.Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria.Age- and tissue-specific changes in mitochondrial and nuclear DNA base excision repair activity in mice: Susceptibility of skeletal muscles to oxidative injury.Mitochondrial base excision repair assaysAssociation of leukocyte mitochondrial DNA content with glioma risk: evidence from a Chinese case-control study.Mitochondrial dna depletion, oxidative stress, and mutation: mechanisms of dysfunction from nucleoside reverse transcriptase inhibitors.Peripheral blood mitochondrial DNA copy number is associated with prostate cancer risk and tumor burden.Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase.Identification and characterization of mitochondrial abasic (AP)-endonuclease in mammalian cells.Single-nucleotide patch base excision repair of uracil in DNA by mitochondrial protein extracts.Mitochondrial DNA alterations in cancer.Deficiency in repair of the mitochondrial genome sensitizes proliferating myoblasts to oxidative damageEndonuclease III and endonuclease VIII conditionally targeted into mitochondria enhance mitochondrial DNA repair and cell survival following oxidative stress.A novel model of double replications and random loss accounts for rearrangements in the Mitogenome of Samariscus latus (Teleostei: Pleuronectiformes).Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repairPOS5 gene of Saccharomyces cerevisiae encodes a mitochondrial NADH kinase required for stability of mitochondrial DNA.Mitochondrial DNA damage is a hallmark of chemically induced and the R6/2 transgenic model of Huntington's diseaseBcl2 inhibition of mitochondrial DNA repair.Disconnecting XRCC1 and DNA ligase IIIMitochondria, oxidative DNA damage, and agingSolution structures of 2 : 1 and 1 : 1 DNA polymerase-DNA complexes probed by ultracentrifugation and small-angle X-ray scattering.'To repair or not to repair - no longer a question': repair of mitochondrial DNA shielding against age and cancer.Mitochondrial DNA damage and the aging process: facts and imaginations.Mitochondrial DNA repair: a critical player in the response of cells of the CNS to genotoxic insults.Long patch base excision repair in mammalian mitochondrial genomesBase excision repair of oxidative DNA damage and association with cancer and aging
P2860
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P2860
Efficient repair of abasic sites in DNA by mitochondrial enzymes.
description
1998 nî lūn-bûn
@nan
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Efficient repair of abasic sites in DNA by mitochondrial enzymes.
@ast
Efficient repair of abasic sites in DNA by mitochondrial enzymes.
@en
type
label
Efficient repair of abasic sites in DNA by mitochondrial enzymes.
@ast
Efficient repair of abasic sites in DNA by mitochondrial enzymes.
@en
prefLabel
Efficient repair of abasic sites in DNA by mitochondrial enzymes.
@ast
Efficient repair of abasic sites in DNA by mitochondrial enzymes.
@en
P2860
P356
P1476
Efficient repair of abasic sites in DNA by mitochondrial enzymes.
@en
P2093
D F Bogenhagen
P2860
P304
P356
10.1128/MCB.18.3.1257
P407
P577
1998-03-01T00:00:00Z