HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells.
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A candidate HIV/AIDS vaccine (MVA-B) lacking vaccinia virus gene C6L enhances memory HIV-1-specific T-cell responsesEmerging concepts in the immunopathogenesis of AIDSInterleukin-21-producing HIV-1-specific CD8 T cells are preferentially seen in elite controllersIntradermal electroporation of naked replicon RNA elicits strong immune responsesImmunogenic profiling in mice of a HIV/AIDS vaccine candidate (MVA-B) expressing four HIV-1 antigens and potentiation by specific gene deletionsComparisons of CD8+ T Cells Specific for Human Immunodeficiency Virus, Hepatitis C Virus, and Cytomegalovirus Reveal Differences in Frequency, Immunodominance, Phenotype, and Interleukin-2 ResponsivenessT-cell exhaustion in chronic hepatitis B infection: current knowledge and clinical significanceStrong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removalPre-existing adenovirus immunity modifies a complex mixed Th1 and Th2 cytokine response to an Ad5/HIV-1 vaccine candidate in humansHIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cellsIncreased Levels of Macrophage Inflammatory Proteins Result in Resistance to R5-Tropic HIV-1 in a Subset of Elite Controllers.CD8(+) T-cell effector function and transcriptional regulation during HIV pathogenesisRecombination-mediated genetic engineering of a bacterial artificial chromosome clone of modified vaccinia virus Ankara (MVA).Coexpression of GM-CSF and antigen in DNA prime-adenoviral vector boost immunization enhances polyfunctional CD8+ T cell responses, whereas expression of GM-CSF antigen fusion protein induces autoimmunityAbundance of early functional HIV-specific CD8+ T cells does not predict AIDS-free survival time.HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.Impaired quality of the hepatitis B virus (HBV)-specific T-cell response in human immunodeficiency virus type 1-HBV coinfectionsiRNA knockdown of PD-L1 and PD-L2 in monocyte-derived dendritic cells only modestly improves proliferative responses to Gag by CD8(+) T cells from HIV-1-infected individuals.Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cellsHIV-1 infection impairs the bronchoalveolar T-cell response to mycobacteria.Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control.Insertion of vaccinia virus C7L host range gene into NYVAC-B genome potentiates immune responses against HIV-1 antigensProstaglandin E2 promotes features of replicative senescence in chronically activated human CD8+ T cells.Proliferation capacity and cytotoxic activity are mediated by functionally and phenotypically distinct virus-specific CD8 T cells defined by interleukin-7R{alpha} (CD127) and perforin expression.IL-2high tissue-resident T cells in the human liver: Sentinels for hepatotropic infection.CD4+ T cells modulate expansion and survival but not functional properties of effector and memory CD8+ T cells induced by malaria sporozoitesCD4+ T cell effects on CD8+ T cell location defined using bioluminescence.Mechanisms of Virologic Control and Clinical Characteristics of HIV+ Elite/Viremic ControllersRelationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infectionTrivalent adenovirus type 5 HIV recombinant vaccine primes for modest cytotoxic capacity that is greatest in humans with protective HLA class I alleles.Potent HIV-specific responses are enriched in a unique subset of CD8+ T cells that coexpresses CD4 on its surfaceEarly and prolonged antiretroviral therapy is associated with an HIV-1-specific T-cell profile comparable to that of long-term non-progressorsDendritic cells exposed to MVA-based HIV-1 vaccine induce highly functional HIV-1-specific CD8(+) T cell responses in HIV-1-infected individuals.IL-2 production correlates with effector cell differentiation in HIV-specific CD8+ T cells.Early skewed distribution of total and HIV-specific CD8+ T-cell memory phenotypes during primary HIV infection is related to reduced antiviral activity and faster disease progressionChanges in function of HIV-specific T-cell responses with increasing time from infection.Immunodominant T-cell responses to dengue virus NS3 are associated with DHF.Immunodominant HIV-1-specific HLA-B- and HLA-C-restricted CD8+ T cells do not differ in polyfunctionality.A high-throughput single-cell analysis of human CD8⁺ T cell functions reveals discordance for cytokine secretion and cytolysis.Clinical validation of IFNγ/IL-10 and IFNγ/IL-2 FluoroSpot assays for the detection of Tr1 T cells and influenza vaccine monitoring in humans.
P2860
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P2860
HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
HIV-1-specific IFN-gamma/IL-2- ...... of HIV-1-specific CD8 T cells.
@ast
HIV-1-specific IFN-gamma/IL-2- ...... of HIV-1-specific CD8 T cells.
@en
type
label
HIV-1-specific IFN-gamma/IL-2- ...... of HIV-1-specific CD8 T cells.
@ast
HIV-1-specific IFN-gamma/IL-2- ...... of HIV-1-specific CD8 T cells.
@en
prefLabel
HIV-1-specific IFN-gamma/IL-2- ...... of HIV-1-specific CD8 T cells.
@ast
HIV-1-specific IFN-gamma/IL-2- ...... of HIV-1-specific CD8 T cells.
@en
P2093
P2860
P356
P1476
HIV-1-specific IFN-gamma/IL-2- ...... of HIV-1-specific CD8 T cells
@en
P2093
Cristina Cellerai
Florence Vallelian
Pierre-Alexandre Bart
Simone C Zimmerli
P2860
P304
P356
10.1073/PNAS.0502393102
P407
P577
2005-05-04T00:00:00Z