Integrating pathway analysis and genetics of gene expression for genome-wide association studies
about
Shared molecular and functional frameworks among five complex human disorders: a comparative study on interactomes linked to susceptibility genesGenetic studies of body mass index yield new insights for obesity biologyHLA-DRB1 reduces the risk of type 2 diabetes mellitus by increased insulin secretionStatistical analysis for genome-wide association studyGenome-wide significant loci: how important are they? Systems genetics to understand heritability of coronary artery disease and other common complex disordersSystems biology approach reveals genome to phenome correlation in type 2 diabetesABC transporters and the proteasome complex are implicated in susceptibility to Stevens-Johnson syndrome and toxic epidermal necrolysis across multiple drugsCombined Use of Genome-Wide Association Data and Correlation Networks Unravels Key Regulators of Primary Metabolism in Arabidopsis thalianaIntegrated enrichment analysis of variants and pathways in genome-wide association studies indicates central role for IL-2 signaling genes in type 1 diabetes, and cytokine signaling genes in Crohn's diseaseLeveraging models of cell regulation and GWAS data in integrative network-based association studiesComparisons of seven algorithms for pathway analysis using the WTCCC Crohn's Disease datasetGenome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architectureAssociation analyses of 249,796 individuals reveal 18 new loci associated with body mass indexIdentification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene ExpressionA meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers.Gene, pathway and network frameworks to identify epistatic interactions of single nucleotide polymorphisms derived from GWAS data.eQTL Mapping Using RNA-seq DataNetwork-based analysis of genome wide association data provides novel candidate genes for lipid and lipoprotein traits.Biomarkers for combat-related PTSD: focus on molecular networks from high-dimensional data.Bimodal distribution of RNA expression levels in human skeletal muscle tissue.Pathway, in silico and tissue-specific expression quantitative analyses of oesophageal squamous cell carcinoma genome-wide association studies data.Genetic variation in the tau protein phosphatase-2A pathway is not associated with Alzheimer's disease risk.Integrating Diverse Types of Genomic Data to Identify Genes that Underlie Adverse Pregnancy PhenotypesMergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems.The pathogenesis of obesity from a genomic and systems biology perspective.An independent component analysis confounding factor correction framework for identifying broad impact expression quantitative trait lociImproving the detection of pathways in genome-wide association studies by combined effects of SNPs from Linkage Disequilibrium blocks.Genetic-epigenetic interactions in cis: a major focus in the post-GWAS eraThe architecture of gene regulatory variation across multiple human tissues: the MuTHER study.Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.Host genetic susceptibility, dysbiosis, and viral triggers in inflammatory bowel disease.Gene set analysis of SNP data: benefits, challenges, and future directionsSNP-based pathway enrichment analysis for genome-wide association studiesIntegrative genomics reveals novel molecular pathways and gene networks for coronary artery disease.A latent model for prioritization of SNPs for functional studies.Identification and validation of genes affecting aortic lesions in miceTrans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLAPathway analysis for genome-wide association study of basal cell carcinoma of the skinIntegrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis.
P2860
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P2860
Integrating pathway analysis and genetics of gene expression for genome-wide association studies
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Integrating pathway analysis a ...... enome-wide association studies
@ast
Integrating pathway analysis a ...... enome-wide association studies
@en
type
label
Integrating pathway analysis a ...... enome-wide association studies
@ast
Integrating pathway analysis a ...... enome-wide association studies
@en
prefLabel
Integrating pathway analysis a ...... enome-wide association studies
@ast
Integrating pathway analysis a ...... enome-wide association studies
@en
P2093
P2860
P1476
Integrating pathway analysis a ...... enome-wide association studies
@en
P2093
Cliona Molony
Eric E Schadt
Lee M Kaplan
P2860
P304
P356
10.1016/J.AJHG.2010.02.020
P407
P577
2010-03-25T00:00:00Z