Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression
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MECHANISMS IN ENDOCRINOLOGY: Alternative splicing: the new frontier in diabetes researchPerspectives on systems biology applications in diabetic kidney diseaseTranslational implications of the β-cell epigenome in diabetes mellitusSystems biology approach reveals genome to phenome correlation in type 2 diabetesGLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein BimIncorporation of protein binding effects into likelihood ratio test for exome sequencing data.Determining effects of non-synonymous SNPs on protein-protein interactions using supervised and semi-supervised learning.A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes.Early prediction of autoimmune (type 1) diabetes.CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients.Complex multi-block analysis identifies new immunologic and genetic disease progression patterns associated with the residual β-cell function 1 year after diagnosis of type 1 diabetes.The importance of the Non Obese Diabetic (NOD) mouse model in autoimmune diabetesNovel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets.Isolation of a Genomic Region Affecting Most Components of Metabolic Syndrome in a Chromosome-16 Congenic Rat Model.On the immense variety and complexity of circumstances conditioning pancreatic β-cell apoptosis in type 1 diabetesPatient complexity and genotype-phenotype correlations in biliary atresia: a cross-sectional analysis.Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic ControlCIKS (Act1 or TRAF3IP2) mediates high glucose-induced endothelial dysfunction.Genotype to phenotype via network analysis.The pancreatic β cell and type 1 diabetes: innocent bystander or active participant?Cellular Signaling Pathways in Insulin Resistance-Systems Biology Analyses of Microarray Dataset Reveals New Drug Target Gene Signatures of Type 2 Diabetes Mellitus.Viral infections in type 1 diabetes mellitus--why the β cells?Pathogenesis of type 1 diabetes: lessons from natural history studies of high-risk individuals.Candidate genes expressed in human islets and their role in the pathogenesis of type 1 diabetes.Candidate genes for type 1 diabetes modulate pancreatic islet inflammation and β-cell apoptosis.Th17 cells in immunity and autoimmunity.Role of vitamin D in acquired immune and autoimmune diseases.Protein-protein interactions and genetic diseases: The interactome.Protein-protein interaction networks (PPI) and complex diseases.Dual Role of Act1 in Keratinocyte Differentiation and Host Defense: TRAF3IP2 Silencing Alters Keratinocyte Differentiation and Inhibits IL-17 ResponsesGenes affecting β-cell function in type 1 diabetes.Of the multiple mechanisms leading to type 1 diabetes, T cell receptor revision may play a prominent role (is type 1 diabetes more than a single disease?).Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis.Identification of new key genes for type 1 diabetes through construction and analysis of protein-protein interaction networks based on blood and pancreatic islet transcriptomes.Effects of the genome on immune regulation in type 1 diabetes.Generation of stem cell-derived β-cells from patients with type 1 diabetes.The Genetic Architecture of Type 1 Diabetes.TRAF5 and TRAF3IP2 gene polymorphisms are associated with Behçet's disease and Vogt-Koyanagi-Harada syndrome: a case-control study.IL-17A increases the expression of proinflammatory chemokines in human pancreatic islets.Type 1 diabetes genome-wide association studies: not to be lost in translation.
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P2860
Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Identification of Novel Type 1 ...... ncreatic Islet Gene Expression
@ast
Identification of Novel Type 1 ...... ncreatic Islet Gene Expression
@en
type
label
Identification of Novel Type 1 ...... ncreatic Islet Gene Expression
@ast
Identification of Novel Type 1 ...... ncreatic Islet Gene Expression
@en
prefLabel
Identification of Novel Type 1 ...... ncreatic Islet Gene Expression
@ast
Identification of Novel Type 1 ...... ncreatic Islet Gene Expression
@en
P2093
P2860
P50
P3181
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P1476
Identification of novel type 1 ...... ncreatic islet gene expression
@en
P2093
Klaus Stensgaard Frederiksen
Lukas A Berchtold
Regine Bergholdt
Tina Fløyel
P2860
P304
P3181
P356
10.2337/DB11-1263
P407
P50
P577
2012-02-16T00:00:00Z