Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression - Wikidata - wikimedia - TriplyDB

Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression

Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression

http://www.wikidata.org/entity/Q30002303

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MECHANISMS IN ENDOCRINOLOGY: Alternative splicing: the new frontier in diabetes research Perspectives on systems biology applications in diabetic kidney disease Translational implications of the β-cell epigenome in diabetes mellitus Systems biology approach reveals genome to phenome correlation in type 2 diabetes GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein Bim Incorporation of protein binding effects into likelihood ratio test for exome sequencing data.Determining effects of non-synonymous SNPs on protein-protein interactions using supervised and semi-supervised learning.A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes.Early prediction of autoimmune (type 1) diabetes.CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients.Complex multi-block analysis identifies new immunologic and genetic disease progression patterns associated with the residual β-cell function 1 year after diagnosis of type 1 diabetes.The importance of the Non Obese Diabetic (NOD) mouse model in autoimmune diabetes Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets.Isolation of a Genomic Region Affecting Most Components of Metabolic Syndrome in a Chromosome-16 Congenic Rat Model.On the immense variety and complexity of circumstances conditioning pancreatic β-cell apoptosis in type 1 diabetes Patient complexity and genotype-phenotype correlations in biliary atresia: a cross-sectional analysis.Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control CIKS (Act1 or TRAF3IP2) mediates high glucose-induced endothelial dysfunction.Genotype to phenotype via network analysis.The pancreatic β cell and type 1 diabetes: innocent bystander or active participant?Cellular Signaling Pathways in Insulin Resistance-Systems Biology Analyses of Microarray Dataset Reveals New Drug Target Gene Signatures of Type 2 Diabetes Mellitus.Viral infections in type 1 diabetes mellitus--why the β cells?Pathogenesis of type 1 diabetes: lessons from natural history studies of high-risk individuals.Candidate genes expressed in human islets and their role in the pathogenesis of type 1 diabetes.Candidate genes for type 1 diabetes modulate pancreatic islet inflammation and β-cell apoptosis.Th17 cells in immunity and autoimmunity.Role of vitamin D in acquired immune and autoimmune diseases.Protein-protein interactions and genetic diseases: The interactome.Protein-protein interaction networks (PPI) and complex diseases.Dual Role of Act1 in Keratinocyte Differentiation and Host Defense: TRAF3IP2 Silencing Alters Keratinocyte Differentiation and Inhibits IL-17 Responses Genes affecting β-cell function in type 1 diabetes.Of the multiple mechanisms leading to type 1 diabetes, T cell receptor revision may play a prominent role (is type 1 diabetes more than a single disease?).Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis.Identification of new key genes for type 1 diabetes through construction and analysis of protein-protein interaction networks based on blood and pancreatic islet transcriptomes.Effects of the genome on immune regulation in type 1 diabetes.Generation of stem cell-derived β-cells from patients with type 1 diabetes.The Genetic Architecture of Type 1 Diabetes.TRAF5 and TRAF3IP2 gene polymorphisms are associated with Behçet's disease and Vogt-Koyanagi-Harada syndrome: a case-control study.IL-17A increases the expression of proinflammatory chemokines in human pancreatic islets.Type 1 diabetes genome-wide association studies: not to be lost in translation.

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Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression

http://www.wikidata.org/entity/Q30002303

description

2012 nî lūn-bûn

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2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2012 թվականի փետրվարին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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Identification of Novel Type 1 ...... ncreatic Islet Gene Expression

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Lukas A Berchtold

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Regine Bergholdt

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Tina Fløyel

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P2860

Gene ontology: tool for the unification of biology

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

STRING 8--a global view on proteins and their functional interactions in 630 organisms

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

CXCR7 functions as a scavenger for CXCL12 and CXCL11

The KEGG resource for deciphering the genome

Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.

An efficient algorithm for large-scale detection of protein families

Network modeling links breast cancer susceptibility and centrosome dysfunction

The function of GRB2 in linking the insulin receptor to Ras signaling pathways

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Caroline Brorsson

Claus Heiner Bang-Berthelsen

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