Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex - Wikidata - wikimedia - TriplyDB

Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex

Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex

http://www.wikidata.org/entity/Q33779586

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PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy Intermediate Filaments as Organizers of Cellular Space: How They Affect Mitochondrial Structure and Function Transporting mitochondria in neurons Cross Talk of Proteostasis and Mitostasis in Cellular Homeodynamics, Ageing, and Disease Alterations in Mitochondrial Quality Control in Alzheimer's Disease Mitochondria-associated membranes as hubs for neurodegeneration MIRO GTPases in Mitochondrial Transport, Homeostasis and Pathology Charcot-Marie-Tooth disease and intracellular traffic Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration Cell signaling and mitochondrial dynamics: Implications for neuronal function and neurodegenerative disease Mitochondrial form and function The axonal transport of mitochondria Reliance of ER-mitochondrial calcium signaling on mitochondrial EF-hand Ca2+ binding proteins: Miros, MICUs, LETM1 and solute carriers Functional consequences of repeated organophosphate exposure: potential non-cholinergic mechanisms Extensive fusion of mitochondria in spinal cord motor neurons Inner membrane fusion mediates spatial distribution of axonal mitochondria Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration.The non-canonical Wnt/PKC pathway regulates mitochondrial dynamics through degradation of the arm-like domain-containing protein Alex3 Alterations of mitochondrial dynamics allow retrograde propagation of locally initiated axonal insults Impulse conduction increases mitochondrial transport in adult mammalian peripheral nerves in vivo Human wild-type full-length tau accumulation disrupts mitochondrial dynamics and the functions via increasing mitofusins.HDAC6 inhibitor blocks amyloid beta-induced impairment of mitochondrial transport in hippocampal neurons Structural coupling of the EF hand and C-terminal GTPase domains in the mitochondrial protein Miro The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast.Mechanisms of mesenchymal stem/stromal cell function Mitochondrial trafficking in neurons Shaping the role of mitochondria in the pathogenesis of Huntington's disease Mitochondrial dynamics and mitochondrial quality control Morphological and bioenergetic demands underlying the mitophagy in post-mitotic neurons: the pink-parkin pathway Mitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degeneration Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge Trafficking kinesin protein (TRAK)-mediated transport of mitochondria in axons of hippocampal neurons Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes Mitochondrial dynamics and motility inside living vascular endothelial cells: role of bioenergetics.Axon degeneration and PGC-1α-mediated protection in a zebrafish model of α-synuclein toxicity The Armc10/SVH gene: genome context, regulation of mitochondrial dynamics and protection against Aβ-induced mitochondrial fragmentation Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy.Mitochondria in Alzheimer's Disease and Diabetes-Associated Neurodegeneration: License to Heal!

P2860

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P2860

Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex

http://www.wikidata.org/entity/Q33779586

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

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name

Mitofusin 2 is necessary for t ...... s with the Miro/Milton complex

@ast

Mitofusin 2 is necessary for t ...... s with the Miro/Milton complex

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type

label

Mitofusin 2 is necessary for t ...... s with the Miro/Milton complex

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Mitofusin 2 is necessary for t ...... s with the Miro/Milton complex

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prefLabel

Mitofusin 2 is necessary for t ...... s with the Miro/Milton complex

@ast

Mitofusin 2 is necessary for t ...... s with the Miro/Milton complex

@en

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P356

JNEUROSCI.6248-09.2010

P1433

Journal of Neuroscience

P1476

Mitofusin 2 is necessary for t ...... s with the Miro/Milton complex

@en

P2093

Albert Misko

http://www.w3.org/2001/XMLSchema#string

Iga Wegorzewska

http://www.w3.org/2001/XMLSchema#string

Robert H Baloh

http://www.w3.org/2001/XMLSchema#string

P2860

OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking

Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

HUMMR, a hypoxia- and HIF-1alpha-inducible protein, alters mitochondrial distribution and transport

OPA1 requires mitofusin 1 to promote mitochondrial fusion

The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport

Dynactin is required for bidirectional organelle transport

The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion.

Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

Mitochondria: dynamic organelles in disease, aging, and development

P304

4232-4240

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scholarly article

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10.1523/JNEUROSCI.6248-09.2010

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12

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30

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Jeffrey Milbrandt

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2010-03-01T00:00:00Z

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42541652

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20335458

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2852190

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