Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes.
about
Stress kinases in the modulation of metabolism and energy balancec-Jun N-Terminal Kinases Mediate a Wide Range of Targets in the Metastatic Cascadec-Jun amino-terminal kinase-1 mediates glucose-responsive upregulation of the RNA editing enzyme ADAR2 in pancreatic beta-cellsJNK3 maintains expression of the insulin receptor substrate 2 (IRS2) in insulin-secreting cells: functional consequences for insulin signaling.Induction of olfaction and cancer-related genes in mice fed a high-fat diet as assessed through the mode-of-action by network identification analysisFunctional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistanceInactivation of JNK1 enhances innate IL-10 production and dampens autoimmune inflammation in the brain.The polygenic nature of inhibitors in hemophilia A: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.Tumor necrosis factor-induced toxic liver injury results from JNK2-dependent activation of caspase-8 and the mitochondrial death pathwayCytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling.Specific splice variants are associated with Parkinson's disease.Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury.JNKs, insulin resistance and inflammation: A possible link between NAFLD and coronary artery disease.JNK inhibitors as anti-inflammatory and neuroprotective agents.Protein kinases: mechanisms and downstream targets in inflammation-mediated obesity and insulin resistance.Proteasome inhibitors, including curcumin, improve pancreatic β-cell function and insulin sensitivity in diabetic mice.Redundant roles for cJun-N-terminal kinase 1 and 2 in interleukin-1beta-mediated reduction and modification of murine hepatic nuclear retinoid X receptor alpha.Converging evidence that sequence variations in the novel candidate gene MAP2K7 (MKK7) are functionally associated with schizophrenia.Diesel exhaust particulates affect cell signaling, mucin profiles, and apoptosis in trachea explants of Balb/C mice.
P2860
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P2860
Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Disruption of the Jnk2 (Mapk9) ...... ouse model of type I diabetes.
@ast
Disruption of the Jnk2 (Mapk9) ...... ouse model of type I diabetes.
@en
type
label
Disruption of the Jnk2 (Mapk9) ...... ouse model of type I diabetes.
@ast
Disruption of the Jnk2 (Mapk9) ...... ouse model of type I diabetes.
@en
prefLabel
Disruption of the Jnk2 (Mapk9) ...... ouse model of type I diabetes.
@ast
Disruption of the Jnk2 (Mapk9) ...... ouse model of type I diabetes.
@en
P2093
P2860
P356
P1476
Disruption of the Jnk2 (Mapk9) ...... ouse model of type I diabetes.
@en
P2093
Aldo A Rossini
Anja Jaeschke
Beth Doran
Dale L Greiner
Donna Neuberg
Judith Reilly
Leonard D Shultz
Mercedes Rincón
Richard A Flavell
Roger J Davis
P2860
P304
P356
10.1073/PNAS.0502143102
P407
P577
2005-05-02T00:00:00Z