A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis.
about
High glucose suppresses human islet insulin biosynthesis by inducing miR-133a leading to decreased polypyrimidine tract binding protein-expressionProtection against cytokine toxicity through endoplasmic reticulum and mitochondrial stress prevention by prostacyclin synthase overexpression in insulin-producing cellsThe neurosurvival factor Humanin inhibits beta-cell apoptosis via signal transducer and activator of transcription 3 activation and delays and ameliorates diabetes in nonobese diabetic miceInterleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis.The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current stateMolecular Events Linking Oxidative Stress and Inflammation to Insulin Resistance and β-Cell DysfunctionThe impact of anti-inflammatory cytokines on the pancreatic β-cellHepatitis C virus infection and type 1 and type 2 diabetes mellitusThe central role of calcium in the effects of cytokines on beta-cell function: implications for type 1 and type 2 diabetesAn Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to PathologyPhysiological effects and therapeutic potential of proinsulin C-peptideIdentification and characterization of secretagogin promoter activityGenetic and functional evidence supporting SUMO4 as a type 1 diabetes susceptibility geneProtective effects of Egyptian cloudy apple juice and apple peel extract on lipid peroxidation, antioxidant enzymes and inflammatory status in diabetic rat pancreasJunB Inhibits ER Stress and Apoptosis in Pancreatic Beta CellsEffects of Imatinib Mesylate (Gleevec) on human islet NF-kappaB activation and chemokine production in vitroZinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein BimInterleukin-1 beta induces posttranslational carboxymethylation and alterations in subnuclear distribution of lamin B in insulin-secreting RINm5F cellsA comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cellsEndoplasmic reticulum stress sensitizes pancreatic beta cells to interleukin-1β-induced apoptosis via Bim/A1 imbalanceHistone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic childrenSTAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammationCytokines tumor necrosis factor-α and interferon-γ induce pancreatic β-cell apoptosis through STAT1-mediated Bim protein activationRole of the mitogen-activated protein kinases in cytokine-mediated inhibition of insulin gene expressionp53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stressPeripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell deathReg3α Overexpression Protects Pancreatic Beta-Cells From Cytokine-Induced Damage and Improves Islet Transplant OutcomeIn vivo islet protection by a nuclear import inhibitor in a mouse model of type 1 diabetesManganese-enhanced magnetic resonance imaging detects declining pancreatic β-cell mass in a cyclophosphamide-accelerated mouse model of type 1 diabetes.The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice.Resolving the conundrum of islet transplantation by linking metabolic dysregulation, inflammation, and immune regulation.Quantitative pancreatic β cell MRI using manganese-enhanced Look-Locker imaging and two-site water exchange analysis.Methylene blue photodynamic therapy induces selective and massive cell death in human breast cancer cells.Protein profiling of pancreatic islets.In silico identification of NF-kappaB-regulated genes in pancreatic beta-cellsCell loss during pseudoislet formation hampers profound improvements in islet lentiviral transduction efficacy for transplantation purposes.Excessive islet NO generation in type 2 diabetic GK rats coincides with abnormal hormone secretion and is counteracted by GLP-1.Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation.
P2860
Q21136357-9565763B-6D8C-4B2A-BB18-44BE9EB55181Q24299562-2CAE3B7E-49C3-45C5-B145-D70C58A5DD46Q24619125-09F07128-7C00-44D4-82E0-EBD1CCB5C8ABQ24812880-C75C59A4-BDFA-4139-BF4B-2D1823285AE0Q25255526-414F2270-E6CE-419D-8368-87AE04CFF647Q26741668-EF312E90-8438-431A-8B91-53E150B451BEQ26800081-819D8111-BCDC-4738-BAD2-0AA538862A90Q26822824-1BC9E165-79F5-464D-9E95-F4F2865F3735Q26829202-7E40D12B-1001-42AA-8E05-97A1C1C9E048Q26860579-AD7A74AB-AE2D-4E12-98E6-0FF0E567E3B4Q27004333-7D0A5B87-9724-44FC-A41C-C6DBF2F8C7DCQ27012286-69451F6C-B029-4F01-88B0-BCB8360463BAQ28272220-2058BBEE-1B8E-4326-9364-021970F4956AQ28275898-A33F5BA9-7248-4FC5-8093-92FA50801092Q28383594-4687BB04-4DA0-4799-B666-6E484EEB5CD2Q28473492-52860227-EE67-4167-A745-81B57D70F689Q28477081-ACC31600-88AC-476D-85A8-E7CDFF28F409Q28566179-33A60E23-BBF3-4C79-B521-A58442AA5A8CQ28571413-DA71E0F5-D536-406B-8A1B-48F6105CC428Q28571930-7A5DD539-9E46-4255-BFFC-0E2FF35C3CECQ28572940-8187EEE2-612C-4BEA-9848-4FE766D64C8AQ28574313-7FAC5AF2-0BE6-4170-AEE9-7E31798A8A6AQ28575131-A17F8B19-3CF3-4A11-9281-1ED12A87AC4DQ28575333-26E689F3-CE32-47B0-9382-0F4047810707Q28579310-07648AAB-5A35-4019-B9BB-C437B905812AQ28579977-A96C917E-7054-4323-B886-50E60E170E1CQ28580759-0D7376CA-93D5-4C40-8088-C2034C35A82DQ28582005-AF4EA2A4-68B3-4158-81FA-17F914566DFCQ28652194-6E6CE56D-77D3-4BDB-8D4A-07B5BBF933BCQ28748969-8E23651A-49B2-4AEC-943A-12276C5D1A09Q30415463-646F2D0B-F3BB-4606-BAF4-34C533427AF1Q30435990-268D293A-65DC-4820-8E8F-7FE760207BAAQ30437086-BF41B284-8B27-4E7F-81B3-17CC922DDF97Q30454821-F7755F9B-3584-4C6C-A10F-678B927E0942Q30842073-C6773A0E-CBD4-41E7-9C68-0C25223424C3Q33267158-765D2DD4-6141-491B-BF30-C35540B50873Q33273973-64027533-EE79-43A6-9B81-D1D62806A62CQ33294626-99D78F6C-2FD4-4052-A364-A90BA7FC6380Q33334446-6F920E86-C9D2-4ABA-AFA4-31F44E0258F0Q33355903-96F1FE81-23A8-4110-997D-756FBF63596A
P2860
A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis.
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis.
@ast
A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis.
@en
A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis.
@nl
type
label
A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis.
@ast
A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis.
@en
A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis.
@nl
prefLabel
A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis.
@ast
A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis.
@en
A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis.
@nl
P356
P1433
P1476
A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis.
@en
P2093
Eizirik DL
Mandrup-Poulsen T
P2888
P304
P356
10.1007/S001250100021
P577
2001-12-01T00:00:00Z
P5875
P6179
1011855813