Exclusive and persistent use of the entry coreceptor CXCR4 by human immunodeficiency virus type 1 from a subject homozygous for CCR5 delta32.
about
The coreceptor mutation CCR5Delta32 influences the dynamics of HIV epidemics and is selected for by HIVViral entry through CXCR4 is a pathogenic factor and therapeutic target in human immunodeficiency virus type 1 diseaseRole for CCR5Delta32 protein in resistance to R5, R5X4, and X4 human immunodeficiency virus type 1 in primary CD4+ cellsEstablishment of a novel CCR5 and CXCR4 expressing CD4+ cell line which is highly sensitive to HIV and suitable for high-throughput evaluation of CCR5 and CXCR4 antagonistsDefinition of the stage of host cell genetic restriction of replication of human immunodeficiency virus type 1 in monocytes and monocyte-derived macrophages by using twins.Bioinformatic analysis of HIV-1 entry and pathogenesis.The biology of CCR5 and CXCR4CCR5Delta32 genotypes in a German HIV-1 seroconverter cohort and report of HIV-1 infection in a CCR5Delta32 homozygous individual.Chimeric SCID-hu Model as a Human Hematopoietic Stem Cell Host That Recapitulates the Effects of HIV-1 on Bone Marrow Progenitors in Infected Patients.Will multiple coreceptors need to be targeted by inhibitors of human immunodeficiency virus type 1 entry?Role of CXCR4 in cell-cell fusion and infection of monocyte-derived macrophages by primary human immunodeficiency virus type 1 (HIV-1) strains: two distinct mechanisms of HIV-1 dual tropism.Chemokine coreceptor usage by diverse primary isolates of human immunodeficiency virus type 1Use of coreceptors other than CCR5 by non-syncytium-inducing adult and pediatric isolates of human immunodeficiency virus type 1 is rare in vitroUse of inhibitors to evaluate coreceptor usage by simian and simian/human immunodeficiency viruses and human immunodeficiency virus type 2 in primary cells.A polymorphism in the regulatory region of the CC-chemokine receptor 5 gene influences perinatal transmission of human immunodeficiency virus type 1 to African-American infantsDonor- and ligand-dependent differences in C-C chemokine receptor 5 reexpression.No selection for CCR5 coreceptor usage during parenteral transmission of macrophagetropic syncytium-inducing human immunodeficiency virus type 1.Mucosal transmission and induction of simian AIDS by CCR5-specific simian/human immunodeficiency virus SHIV(SF162P3)A novel CXCR4-selective high-affinity fluorescent probe and its application in competitive binding assaysInhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5.Macrophage-tropic simian/human immunodeficiency virus chimeras use CXCR4, not CCR5, for infections of rhesus macaque peripheral blood mononuclear cells and alveolar macrophagesA human immunodeficiency virus type 1 isolate from an infected person homozygous for CCR5Delta32 exhibits dual tropism by infecting macrophages and MT2 cells via CXCR4.Genetic and functional analysis of R5X4 human immunodeficiency virus type 1 envelope glycoproteins derived from two individuals homozygous for the CCR5delta32 alleleTwo mechanisms for human immunodeficiency virus type 1 inhibition by N-terminal modifications of RANTESSelective transmission of R5 HIV-1 variants: where is the gatekeeper?Human immunodeficiency virus type 1 envelope-mediated neuronal death: uncoupling of viral replication and neurotoxicityLoss of naïve cells accompanies memory CD4+ T-cell depletion during long-term progression to AIDS in Simian immunodeficiency virus-infected macaques.Host factors influencing susceptibility to HIV infection and AIDS progression.Genetic factors for aids progression: Analyses of HIV-1 resistant genes in India and therapeutic potentials of novel catalytic RNA and DNA moleculesCCR5Delta32 59537-G/A promoter polymorphism is associated with low translational efficiency and the loss of CCR5Delta32 protective effectsR5X4 viruses are evolutionary, functional, and antigenic intermediates in the pathway of a simian-human immunodeficiency virus coreceptor switchMode of transmission affects the sensitivity of human immunodeficiency virus type 1 to restriction by rhesus TRIM5alpha.Topical application of entry inhibitors as "virustats" to prevent sexual transmission of HIV infection.HIV-1 Nef responsiveness is determined by Env variable regions involved in trimer association and correlates with neutralization sensitivityC-C chemokine receptor type five (CCR5): An emerging target for the control of HIV infection.Inhibition of human immunodeficiency virus replication by a dual CCR5/CXCR4 antagonist.Maraviroc in the treatment of HIV infection.Stem cell-based approaches to treating HIV infection.Coreceptor use in nonhuman primate models of HIV infection.Pathogenesis of HIV Infection.
P2860
Q22066237-93626A17-8C98-48BD-A000-78881A343775Q24524292-B7461902-65B3-42D5-9086-427C20502AF9Q24608200-FBFA556F-43D1-4EAF-888C-E53CBE994B87Q24802476-ADE6746F-5EDA-4FD8-8DD8-6009FB15BE01Q27469707-77A68F7D-697E-4610-849C-162A10CD5A8FQ27693321-65B54E45-2A34-4F70-A5F2-1AD63C14A2F9Q29012920-BD762FD9-458D-4274-AF54-DD1826326069Q33354082-D14174B1-0535-4624-A658-1C78CE68C2B4Q33382126-0969CE20-1B6C-4CB4-A8C4-85F1752ED6CCQ33645423-689A1690-1F9A-4808-8907-E84439E6085DQ33648601-86175AAE-EA67-4306-8DC6-4FCAB575E4B9Q33785473-9CF124E6-6A06-4021-99EE-BE371BF3CB6AQ33785490-82DB44E1-FB52-4276-9D3C-368DCDF479E8Q33808728-AE819D5E-CAA6-4C9F-B2A2-FC8D0B27C6DBQ33825328-DE794104-23EE-4497-BBB8-0C121DAE9E8BQ33835337-F9EBCD7C-C239-4762-9E80-880414E15207Q33854857-5420D971-6082-412E-8B14-9E54DF3002C1Q33855093-53338060-28C5-48DA-857B-5D1A4E4A2ED7Q34089069-4C9FA8F8-FCC7-4A3B-91B1-4A44C966DD5EQ34169244-3CC06005-CFD0-4682-85A2-60480A0D9899Q34226885-92134ABD-D598-455E-949C-2196E453F0D8Q34333673-A862C5A6-A5BE-485A-BB6D-C9DF53517997Q34545588-AD6F3099-13F9-490A-B648-A9A8C7FF7666Q34823587-25F9EE42-F2A5-49F1-B11D-4D328BEBBF95Q35018140-4ED3A8AF-A961-4A8F-BB9D-0E27122F8ECAQ35020086-7825D2CF-D68A-4131-A418-89F224850EC2Q35634983-F8573661-0B35-4D66-BAE1-3207284FDFAFQ35995936-A6536277-4BCF-4939-81C8-1EDCA7999FE7Q36265627-B574D9A8-09F0-4922-8C4C-E0393910CF04Q36483857-9981312C-4CBC-43C0-97DF-1E5AE28C1707Q36747765-1002994C-0C91-4A0D-AEDD-D4F73D37954EQ36949816-9380598F-D7AB-4A09-A8D5-639FE1DC0C64Q37088591-59388959-E1DE-45D1-99D5-9D803C45C19CQ37396102-8302556E-FFA5-4C74-ABA5-1DE5EEB1002FQ37463869-A5A95333-33A9-47A4-B67E-7FBCB293C451Q37596456-8FAF5E8A-F065-4D01-90C9-DFE74FC5166EQ37634319-A648E570-62D4-4302-9BD2-D1794ACF3785Q37829631-AE6A0FA7-E8C1-4CD3-9F70-BBF04CF8DC8EQ37834099-04BABE23-662B-45B5-8442-0E864796C3B7Q38182590-D7A036A9-7887-4784-AE69-341E7FE70EDF
P2860
Exclusive and persistent use of the entry coreceptor CXCR4 by human immunodeficiency virus type 1 from a subject homozygous for CCR5 delta32.
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Exclusive and persistent use o ...... t homozygous for CCR5 delta32.
@ast
Exclusive and persistent use o ...... t homozygous for CCR5 delta32.
@en
type
label
Exclusive and persistent use o ...... t homozygous for CCR5 delta32.
@ast
Exclusive and persistent use o ...... t homozygous for CCR5 delta32.
@en
prefLabel
Exclusive and persistent use o ...... t homozygous for CCR5 delta32.
@ast
Exclusive and persistent use o ...... t homozygous for CCR5 delta32.
@en
P2093
P2860
P1433
P1476
Exclusive and persistent use o ...... ct homozygous for CCR5 delta32
@en
P2093
D R Littman
J A Nelson
J R Mascola
N L Michael
R Swanstrom
S J O'Brien
P2860
P304
P577
1998-07-01T00:00:00Z