Identical Mr 70,000 S6 kinase is activated biphasically by epidermal growth factor: a phosphopeptide that characterizes the late phase
about
Cloning of the mitogen-activated S6 kinase from rat liver reveals an enzyme of the second messenger subfamily.A single gene encodes two isoforms of the p70 S6 kinase: activation upon mitogenic stimulation.Identification and early activation of a Xenopus laevis p70s6k following progesterone-induced meiotic maturation.Activation of p70s6k is associated with phosphorylation of four clustered sites displaying Ser/Thr-Pro motifsActivation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors.S6 phosphorylation and the p70s6k/p85s6k.Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites.Growth hormone activates mitogen-activated protein kinase and S6 kinase and promotes intracellular tyrosine phosphorylation in 3T3-F442A preadipocytes
P2860
Q30824759-4FFEB837-E224-4E69-9EE1-F0A92F7E63D8Q30846613-18BE9590-372E-4B9A-BF62-D6262E6F9C53Q33937723-5CB2D45C-D0C7-4B1C-B862-AEB0690CCD24Q37143272-FD916C35-83A7-4FA7-8569-E59D699BA46CQ37549774-B6F982AE-52BE-4D7C-97CC-EC78EE1B6244Q40499781-36453692-972A-4F64-8063-2E2740274459Q41666761-5CD83CA4-0C30-404E-9AFD-D8C94D9AD509Q41997617-F65C7916-1952-4EFE-9CB8-D728AFE9C0A1
P2860
Identical Mr 70,000 S6 kinase is activated biphasically by epidermal growth factor: a phosphopeptide that characterizes the late phase
description
1990 nî lūn-bûn
@nan
1990 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Identical Mr 70,000 S6 kinase ...... t characterizes the late phase
@ast
Identical Mr 70,000 S6 kinase ...... t characterizes the late phase
@en
type
label
Identical Mr 70,000 S6 kinase ...... t characterizes the late phase
@ast
Identical Mr 70,000 S6 kinase ...... t characterizes the late phase
@en
prefLabel
Identical Mr 70,000 S6 kinase ...... t characterizes the late phase
@ast
Identical Mr 70,000 S6 kinase ...... t characterizes the late phase
@en
P2860
P356
P1476
Identical Mr 70,000 S6 kinase ...... t characterizes the late phase
@en
P2860
P304
P356
10.1073/PNAS.87.18.7040
P407
P577
1990-09-01T00:00:00Z