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Dual requirement for a newly identified phosphorylation site in p70s6kCrystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motifAmino acid-induced stimulation of translation initiation in rat skeletal muscleNovel cross talk between MEK and S6K2 in FGF-2 induced proliferation of SCLC cellsAcute alcohol intoxication enhances myocardial eIF4G phosphorylation despite reducing mTOR signalingRegulation of neuronal mRNA translation by CaM-kinase I phosphorylation of eIF4GIIThe Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytesInsulin activates a PD 098059-sensitive kinase that is involved in the regulation of p70S6K and PHAS-I.Luteinizing hormone stimulates mammalian target of rapamycin signaling in bovine luteal cells via pathways independent of AKT and mitogen-activated protein kinase: modulation of glycogen synthase kinase 3 and AMP-activated protein kinaseDown-regulation of RpS21, a putative translation initiation factor interacting with P40, produces viable minute imagos and larval lethality with overgrown hematopoietic organs and imaginal discs.A new functional role for mechanistic/mammalian target of rapamycin complex 1 (mTORC1) in the circadian regulation of L-type voltage-gated calcium channels in avian cone photoreceptorsPhenotypically Dormant and Immature Leukaemia Cells Display Increased Ribosomal Protein S6 PhosphorylationThe insulin-induced signalling pathway leading to S6 and initiation factor 4E binding protein 1 phosphorylation bifurcates at a rapamycin-sensitive point immediately upstream of p70s6k.Mechanisms of nordihydroguaiaretic acid-induced growth inhibition and apoptosis in human cancer cellsMorphoproteomic confirmation of a constitutively activated mTOR pathway in high grade prostatic intraepithelial neoplasia and prostate cancer.The Drosophila p70s6k homolog exhibits conserved regulatory elements and rapamycin sensitivity.Gene expression alterations in the medial prefrontal cortex and blood cells in a mouse model of depression during menopausePhospho-p70S6K and cdc2/cdk1 as therapeutic targets for diffuse large B-cell lymphoma.Characterization and regulation of mechanical loading-induced compensatory muscle hypertrophy.Modulation of oxidative stress and tau phosphorylation by the mTOR activator phosphatidic acid in SH-SY5Y cells.A phosphatidylinositol 3-kinase docking site in the cytoplasmic tail of the Jaagsiekte sheep retrovirus transmembrane protein is essential for envelope-induced transformation of NIH 3T3 cells.Enterolactone inhibits insulin-like growth factor-1 receptor signaling in human prostatic carcinoma PC-3 cells.Evidence for two catalytically active kinase domains in pp90rsk.The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases.Parallel increase in p70 kinase activation and tau phosphorylation (S262) with Abeta overproduction.P70 S6 kinase mediates tau phosphorylation and synthesis.Differential regulation of the p70 S6 kinase pathway by interferon alpha (IFNalpha) and imatinib mesylate (STI571) in chronic myelogenous leukemia cellsActivation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons.Effect of ethanol on protein kinase Czeta and p70S6 kinase activation by carbachol: a possible mechanism for ethanol-induced inhibition of glial cell proliferation.Hydrogen peroxide activates p70(S6k) signaling pathway.The FKBP12-rapamycin-binding domain is required for FKBP12-rapamycin-associated protein kinase activity and G1 progression.Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.Analysis of the signaling pathway involved in the regulation of hexokinase II gene transcription by insulin.The phosphodiesterase inhibitor SQ 20006 selectively blocks mitogen activation of p70S6k and transition to S phase of the cell division cycle without affecting the steady state phosphorylation of eIF-4E.Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites.Activation of S6 kinase in human neutrophils by calcium pyrophosphate dihydrate crystals: protein kinase C-dependent and phosphatidylinositol-3-kinase-independent pathways.Muscarinic receptor-mediated activation of p70 S6 kinase 1 (S6K1) in 1321N1 astrocytoma cells: permissive role of phosphoinositide 3-kinase.Meal feeding enhances formation of eIF4F in skeletal muscle: role of increased eIF4E availability and eIF4G phosphorylation.Removal of S6K1 and S6K2 leads to divergent alterations in learning, memory, and synaptic plasticity.Rapamycin dissociates p70(S6K) activation from DNA synthesis stimulated by bombesin and insulin in Swiss 3T3 cells.
P2860
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P2860
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh
1994年學術文章
@zh-hant
name
S6 phosphorylation and the p70s6k/p85s6k.
@en
type
label
S6 phosphorylation and the p70s6k/p85s6k.
@en
prefLabel
S6 phosphorylation and the p70s6k/p85s6k.
@en
P2860
P1476
S6 phosphorylation and the p70s6k/p85s6k.
@en
P2093
P2860
P304
P356
10.3109/10409239409083485
P577
1994-01-01T00:00:00Z