Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling. - Wikidata - wikimedia - TriplyDB

Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling.

Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling.

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Kynurenines in CNS disease: regulation by inflammatory cytokines Influence of light on aryl hydrocarbon receptor signaling and consequences in drug metabolism, physiology and disease Clinical significance of T cell metabolic reprogramming in cancer Endotoxin-Induced Tryptophan Degradation along the Kynurenine Pathway: The Role of Indolamine 2,3-Dioxygenase and Aryl Hydrocarbon Receptor-Mediated Immunosuppressive Effects in Endotoxin Tolerance and Cancer and Its Implications for Immunoparalysis Aryl hydrocarbon receptor control of adaptive immunity Kynurenines in the mammalian brain: when physiology meets pathology Toward understanding the role of aryl hydrocarbon receptor in the immune system: current progress and future trends AhR-Mediated, Non-Genomic Modulation of IDO1 Function Changing the face of kynurenines and neurotoxicity: therapeutic considerations The organic anion transporter (OAT) family: a systems biology perspective Elevated cerebrospinal fluid kynurenic acid levels in patients with tick-borne encephalitis The aryl hydrocarbon receptor-activating effect of uremic toxins from tryptophan metabolism: a new concept to understand cardiovascular complications of chronic kidney disease Ah Receptor Pathway Intricacies; Signaling Through Diverse Protein Partners and DNA-Motifs Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water Nrf2 protects against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced oxidative injury and steatohepatitis Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor Gene-environment interactions in male reproductive health: special reference to the aryl hydrocarbon receptor signaling pathway Chemopreventive Metabolites Are Correlated with a Change in Intestinal Microbiota Measured in A-T Mice and Decreased Carcinogenesis Host-microbiome interactions: the aryl hydrocarbon receptor and the central nervous system Immunological Relevance of the Coevolution of IDO1 and AHR Targeted Deletion of Kynurenine 3-Monooxygenase in Mice: A NEW TOOL FOR STUDYING KYNURENINE PATHWAY METABOLISM IN PERIPHERY AND BRAIN Three-factor models versus time series models: quantifying time-dependencies of interactions between stimuli in cell biology and psychobiology for short longitudinal data.Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR.Kynurenine Pathway of Tryptophan Metabolism: Regulatory and Functional Aspects.The role of placental tryptophan catabolism Aryl hydrocarbon receptor antagonism mitigates cytokine-mediated inflammatory signalling in primary human fibroblast-like synoviocytes.Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells The Aryl Hydrocarbon Receptor: A Target for Breast Cancer Therapy.Endogenous aryl hydrocarbon receptor promotes basal and inducible expression of tumor necrosis factor target genes in MCF-7 cancer cells An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells.Kynurenic acid inhibits colon cancer proliferation in vitro: effects on signaling pathways.IDO is a nodal pathogenic driver of lung cancer and metastasis development.Photo-oxidation products of skin surface squalene mediate metabolic and inflammatory responses to solar UV in human keratinocytes.Ah receptor antagonism inhibits constitutive and cytokine inducible IL6 production in head and neck tumor cell lines.Xenobiotic metabolism, disposition, and regulation by receptors: from biochemical phenomenon to predictors of major toxicities Remote ischaemic preconditioning: closer to the mechanism?Utility of kynurenic acid for non-invasive detection of metastatic spread to lymph nodes in non-small cell lung cancer Aryl hydrocarbon receptor-null allele mice have hematopoietic stem/progenitor cells with abnormal characteristics and functions.Microbiome-derived tryptophan metabolites and their aryl hydrocarbon receptor-dependent agonist and antagonist activities.Anti-scarring properties of different tryptophan derivatives

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P2860

Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling.

http://www.wikidata.org/entity/Q33792422

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2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Kynurenic acid is a potent end ...... nce of inflammatory signaling.

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Kynurenic acid is a potent end ...... nce of inflammatory signaling.

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Kynurenic acid is a potent end ...... nce of inflammatory signaling.

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Kynurenic acid is a potent end ...... nce of inflammatory signaling.

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Toxicological Sciences

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Kynurenic acid is a potent end ...... nce of inflammatory signaling.

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Brett C DiNatale

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Colin A Flaveny

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Curtis J Omiecinski

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Elizabeth M Laurenzana

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Gary H Perdew

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Iain A Murray

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Jennifer C Schroeder

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Tejas S Lahoti

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P2860

Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity

Linking dioxins to diabetes: epidemiology and biologic plausibility

Indirubin and indigo are potent aryl hydrocarbon receptor ligands present in human urine

Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals

Association of the Ah receptor with the 90-kDa heat shock protein

Characterization of the Ah receptor mediating aryl hydrocarbon hydroxylase induction in the human liver cell line Hep G2

The aryl hydrocarbon receptor complex and the control of gene expression

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

Gene expression profiling and differentiation assessment in primary human hepatocyte cultures, established hepatoma cell lines, and human liver tissues

Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms.

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89-97

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10.1093/TOXSCI/KFQ024

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1

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115

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2010-01-27T00:00:00Z

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41165956

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20106948

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2855350

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