Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling.
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Kynurenines in CNS disease: regulation by inflammatory cytokinesInfluence of light on aryl hydrocarbon receptor signaling and consequences in drug metabolism, physiology and diseaseClinical significance of T cell metabolic reprogramming in cancerEndotoxin-Induced Tryptophan Degradation along the Kynurenine Pathway: The Role of Indolamine 2,3-Dioxygenase and Aryl Hydrocarbon Receptor-Mediated Immunosuppressive Effects in Endotoxin Tolerance and Cancer and Its Implications for ImmunoparalysisAryl hydrocarbon receptor control of adaptive immunityKynurenines in the mammalian brain: when physiology meets pathologyToward understanding the role of aryl hydrocarbon receptor in the immune system: current progress and future trendsAhR-Mediated, Non-Genomic Modulation of IDO1 FunctionChanging the face of kynurenines and neurotoxicity: therapeutic considerationsThe organic anion transporter (OAT) family: a systems biology perspectiveElevated cerebrospinal fluid kynurenic acid levels in patients with tick-borne encephalitisThe aryl hydrocarbon receptor-activating effect of uremic toxins from tryptophan metabolism: a new concept to understand cardiovascular complications of chronic kidney diseaseAh Receptor Pathway Intricacies; Signaling Through Diverse Protein Partners and DNA-MotifsComparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking waterNrf2 protects against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced oxidative injury and steatohepatitisExactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptorGene-environment interactions in male reproductive health: special reference to the aryl hydrocarbon receptor signaling pathwayChemopreventive Metabolites Are Correlated with a Change in Intestinal Microbiota Measured in A-T Mice and Decreased CarcinogenesisHost-microbiome interactions: the aryl hydrocarbon receptor and the central nervous systemImmunological Relevance of the Coevolution of IDO1 and AHRTargeted Deletion of Kynurenine 3-Monooxygenase in Mice: A NEW TOOL FOR STUDYING KYNURENINE PATHWAY METABOLISM IN PERIPHERY AND BRAINThree-factor models versus time series models: quantifying time-dependencies of interactions between stimuli in cell biology and psychobiology for short longitudinal data.Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR.Kynurenine Pathway of Tryptophan Metabolism: Regulatory and Functional Aspects.The role of placental tryptophan catabolismAryl hydrocarbon receptor antagonism mitigates cytokine-mediated inflammatory signalling in primary human fibroblast-like synoviocytes.Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cellsThe Aryl Hydrocarbon Receptor: A Target for Breast Cancer Therapy.Endogenous aryl hydrocarbon receptor promotes basal and inducible expression of tumor necrosis factor target genes in MCF-7 cancer cellsAn interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells.Kynurenic acid inhibits colon cancer proliferation in vitro: effects on signaling pathways.IDO is a nodal pathogenic driver of lung cancer and metastasis development.Photo-oxidation products of skin surface squalene mediate metabolic and inflammatory responses to solar UV in human keratinocytes.Ah receptor antagonism inhibits constitutive and cytokine inducible IL6 production in head and neck tumor cell lines.Xenobiotic metabolism, disposition, and regulation by receptors: from biochemical phenomenon to predictors of major toxicitiesRemote ischaemic preconditioning: closer to the mechanism?Utility of kynurenic acid for non-invasive detection of metastatic spread to lymph nodes in non-small cell lung cancerAryl hydrocarbon receptor-null allele mice have hematopoietic stem/progenitor cells with abnormal characteristics and functions.Microbiome-derived tryptophan metabolites and their aryl hydrocarbon receptor-dependent agonist and antagonist activities.Anti-scarring properties of different tryptophan derivatives
P2860
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P2860
Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Kynurenic acid is a potent end ...... nce of inflammatory signaling.
@ast
Kynurenic acid is a potent end ...... nce of inflammatory signaling.
@en
type
label
Kynurenic acid is a potent end ...... nce of inflammatory signaling.
@ast
Kynurenic acid is a potent end ...... nce of inflammatory signaling.
@en
prefLabel
Kynurenic acid is a potent end ...... nce of inflammatory signaling.
@ast
Kynurenic acid is a potent end ...... nce of inflammatory signaling.
@en
P2093
P2860
P356
P1476
Kynurenic acid is a potent end ...... nce of inflammatory signaling.
@en
P2093
Brett C DiNatale
Colin A Flaveny
Curtis J Omiecinski
Elizabeth M Laurenzana
Gary H Perdew
Iain A Murray
Jennifer C Schroeder
Tejas S Lahoti
P2860
P356
10.1093/TOXSCI/KFQ024
P577
2010-01-27T00:00:00Z