c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway.

c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway.

Item
http://www.wikidata.org/entity/Q33796333
Ubiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global ProfilingRINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesisAPC(Cdc20) suppresses apoptosis through targeting Bim for ubiquitination and destruction.Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomyRapidly fatal myeloproliferative disorders in mice with deletion of Casitas B-cell lymphoma (Cbl) and Cbl-b in hematopoietic stem cells.The loss of Cbl-phosphatidylinositol 3-kinase interaction perturbs RANKL-mediated signaling, inhibiting bone resorption and promoting osteoclast survival.Indispensable roles of mammalian Cbl family proteins as negative regulators of protein tyrosine kinase signaling: Insights from in vivo modelsCbl-b-regulated extracellular signal-regulated kinase signaling is involved in the shikonin-induced apoptosis of lung cancer cells in vitro.Abrogation of Cbl-PI3K interaction increases bone formation and osteoblast proliferation.Targeting Cdc20 as a novel cancer therapeutic strategy.Shaping the T-cell repertoire: a matter of life and death.Ubiquitin ligase Cbl-b is involved in icotinib (BPI-2009H)-induced apoptosis and G1 phase arrest of EGFR mutation-positive non-small-cell lung cancer.
P2860

c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway.

Item
http://www.wikidata.org/entity/Q33796333
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
c-Cbl promotes T cell receptor ...... inositol 3-kinase/Akt pathway.
@ast
c-Cbl promotes T cell receptor ...... inositol 3-kinase/Akt pathway.
@en
type
label
c-Cbl promotes T cell receptor ...... inositol 3-kinase/Akt pathway.
@ast
c-Cbl promotes T cell receptor ...... inositol 3-kinase/Akt pathway.
@en
prefLabel
c-Cbl promotes T cell receptor ...... inositol 3-kinase/Akt pathway.
@ast
c-Cbl promotes T cell receptor ...... inositol 3-kinase/Akt pathway.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
c-Cbl promotes T cell receptor ...... inositol 3-kinase/Akt pathway.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932