Accessory proteins stabilize the acceptor complex for synaptobrevin, the 1:1 syntaxin/SNAP-25 complex
about
Mechanical unzipping and rezipping of a single SNARE complex reveals hysteresis as a force-generating mechanismComplexin controls the force transfer from SNARE complexes to membranes in fusionMunc18-1 binding to the neuronal SNARE complex controls synaptic vesicle primingComplexins: small but capableDistinct initial SNARE configurations underlying the diversity of exocytosisSingle-molecule FRET study of SNARE-mediated membrane fusionResident CAPS on dense-core vesicles docks and primes vesicles for fusionMolecular mechanism of the synaptotagmin–SNARE interaction in Ca2+-triggered vesicle fusionThe Crystal Structure of a Munc13 C-terminal Module Exhibits a Remarkable Similarity to Vesicle Tethering FactorsMunc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complexVesicle fusion probability is determined by the specific interactions of munc18Disordered proteinaceous machinesAn extended helical conformation in domain 3a of Munc18-1 provides a template for SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex assembly.The destructive effect of botulinum neurotoxins on the SNARE protein: SNAP-25 and synaptic membrane fusion.Reconstituting SNARE-mediated membrane fusion at the single liposome level.Fluorescence applications in molecular neurobiologyImmobilization of proteins for single-molecule fluorescence resonance energy transfer measurements of conformation and dynamics.Detecting the conformation of individual proteins in live cells.t-SNARE protein conformations patterned by the lipid microenvironment.In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter releaseAccessory alpha-helix of complexin I can displace VAMP2 locally in the complexin-SNARE quaternary complex.Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4Vesicle-associated membrane protein (VAMP) cleavage by a new metalloprotease from the Brazilian scorpion Tityus serrulatusSingle-molecule studies of the neuronal SNARE fusion machinery.Real-time visualization of complexin during single exocytic events.Docking, not fusion, as the rate-limiting step in a SNARE-driven vesicle fusion assayA role of complexin-lipid interactions in membrane fusion.Mitigating unwanted photophysical processes for improved single-molecule fluorescence imaging.Complexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanismsSingle-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex.At the junction of SNARE and SM protein function.Low-resolution solution structures of Munc18:Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide.Novel interactions of CAPS (Ca2+-dependent activator protein for secretion) with the three neuronal SNARE proteins required for vesicle fusion.Single reconstituted neuronal SNARE complexes zipper in three distinct stages.Four-color single-molecule fluorescence with noncovalent dye labeling to monitor dynamic multimolecular complexes.Beyond the random coil: stochastic conformational switching in intrinsically disordered proteins.Stimulus-induced S-nitrosylation of Syntaxin 4 impacts insulin granule exocytosisReluctance to membrane binding enables accessibility of the synaptobrevin SNARE motif for SNARE complex formationResolving the function of distinct Munc18-1/SNARE protein interaction modes in a reconstituted membrane fusion assay.Binding of the complexin N terminus to the SNARE complex potentiates synaptic-vesicle fusogenicity.
P2860
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P2860
Accessory proteins stabilize the acceptor complex for synaptobrevin, the 1:1 syntaxin/SNAP-25 complex
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Accessory proteins stabilize t ...... e 1:1 syntaxin/SNAP-25 complex
@ast
Accessory proteins stabilize t ...... e 1:1 syntaxin/SNAP-25 complex
@en
type
label
Accessory proteins stabilize t ...... e 1:1 syntaxin/SNAP-25 complex
@ast
Accessory proteins stabilize t ...... e 1:1 syntaxin/SNAP-25 complex
@en
prefLabel
Accessory proteins stabilize t ...... e 1:1 syntaxin/SNAP-25 complex
@ast
Accessory proteins stabilize t ...... e 1:1 syntaxin/SNAP-25 complex
@en
P2093
P2860
P1433
P1476
Accessory proteins stabilize t ...... e 1:1 syntaxin/SNAP-25 complex
@en
P2093
Keith Weninger
Mark E Bowen
Steven Chu
Ucheor B Choi
P2860
P304
P356
10.1016/J.STR.2007.12.010
P577
2008-02-01T00:00:00Z