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Reduced sensitivity of influenza A (H5N1) to oseltamivir

Reduced sensitivity of influenza A (H5N1) to oseltamivir

http://www.wikidata.org/entity/Q33800864

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Glycyrrhizin exerts antioxidative effects in H5N1 influenza A virus-infected cells and inhibits virus replication and pro-inflammatory gene expression Effect of neuraminidase inhibitor-resistant mutations on pathogenicity of clade 2.2 A/Turkey/15/06 (H5N1) influenza virus in ferrets Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants Influenza neuraminidase inhibitors: antiviral action and mechanisms of resistance Human-like receptor specificity does not affect the neuraminidase-inhibitor susceptibility of H5N1 influenza viruses Efficacy of the new neuraminidase inhibitor CS-8958 against H5N1 influenza viruses Influenza A H5N1 clade 2.3.4 virus with a different antiviral susceptibility profile replaced clade 1 virus in humans in northern Vietnam Oseltamivir is adequately absorbed following nasogastric administration to adult patients with severe H5N1 influenza I222 Neuraminidase mutations further reduce oseltamivir susceptibility of Indonesian Clade 2.1 highly pathogenic Avian Influenza A(H5N1) viruses Antiviral susceptibility of highly pathogenic avian influenza A(H5N1) viruses isolated from poultry, Vietnam, 2009-2011.Avian influenza A H5N1 virus: a continuous threat to humans.Avian influenza pandemic preparedness: developing prepandemic and pandemic vaccines against a moving target Avian influenza virus in pregnancy.Effective, robust design of community mitigation for pandemic influenza: a systematic examination of proposed US guidance.Detection of molecular markers of antiviral resistance in influenza A (H5N1) viruses using a pyrosequencing method.Susceptibility of highly pathogenic H5N1 influenza viruses to the neuraminidase inhibitor oseltamivir differs in vitro and in a mouse model.Safety and immunogenicity of multiple and higher doses of an inactivated influenza A/H5N1 vaccine.Detection of molecular markers of drug resistance in 2009 pandemic influenza A (H1N1) viruses by pyrosequencing.In vitro antiviral activity of favipiravir (T-705) against drug-resistant influenza and 2009 A(H1N1) viruses.Molecular dynamics simulation of oseltamivir resistance in neuraminidase of avian influenza H5N1 virus.Activation of the innate immune system provides broad-spectrum protection against influenza A viruses with pandemic potential in mice.Treatment options for H5N1: lessons learned from the H1N1 pandemic.Neuraminidase inhibitor sensitivity and receptor-binding specificity of Cambodian clade 1 highly pathogenic H5N1 influenza virus A(H5N1) Virus Evolution in South East Asia.Decreased neuraminidase activity is important for the adaptation of H5N1 influenza virus to human airway epithelium.Antiviral resistance among highly pathogenic influenza A (H5N1) viruses isolated worldwide in 2002-2012 shows need for continued monitoring.Pseudovirus-based neuraminidase inhibition assays reveal potential H5N1 drug-resistant mutations.Characterization of the influenza A H5N1 viruses of the 2008-09 outbreaks in India reveals a third introduction and possible endemicity.Enzymatic properties of the neuraminidase of seasonal H1N1 influenza viruses provide insights for the emergence of natural resistance to oseltamivir.Intramuscularly administered neuraminidase inhibitor peramivir is effective against lethal H5N1 influenza virus in mice Real time enzyme inhibition assays provide insights into differences in binding of neuraminidase inhibitors to wild type and mutant influenza viruses A molecular and antigenic survey of H5N1 highly pathogenic avian influenza virus isolates from smallholder duck farms in Central Java, Indonesia during 2007-2008.New treatments for influenza Defective interfering virus protects elderly mice from influenza Effects of flavonoid-induced oxidative stress on anti-H5N1 influenza a virus activity exerted by baicalein and biochanin A.Mast cell-induced lung injury in mice infected with H5N1 influenza virus.Findings from a household randomized controlled trial of hand washing and face masks to reduce influenza transmission in Bangkok, Thailand Insight into alternative approaches for control of avian influenza in poultry, with emphasis on highly pathogenic H5N1 Oseltamivir and inhaled zanamivir as influenza prophylaxis in Thai health workers: a randomized, double-blind, placebo-controlled safety trial over 16 weeks.Molecular mechanisms underlying oseltamivir resistance mediated by an I117V substitution in the neuraminidase of subtype H5N1 avian influenza A viruses.

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P2860

Reduced sensitivity of influenza A (H5N1) to oseltamivir

http://www.wikidata.org/entity/Q33800864

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2007 nî lūn-bûn

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2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Reduced sensitivity of influenza A (H5N1) to oseltamivir

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Reduced sensitivity of influenza A (H5N1) to oseltamivir

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Reduced sensitivity of influenza A (H5N1) to oseltamivir

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Reduced sensitivity of influenza A (H5N1) to oseltamivir

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Reduced sensitivity of influenza A (H5N1) to oseltamivir

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Reduced sensitivity of influenza A (H5N1) to oseltamivir

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Emerging Infectious Diseases

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Reduced sensitivity of influenza A (H5N1) to oseltamivir

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Jennifer L McKimm-Breschkin

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Michael A Johnson

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Paul W Selleck

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Tri Bhakti Usman

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P2860

Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase

Avian flu: isolation of drug-resistant H5N1 virus.

The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.

Natural variation can significantly alter the sensitivity of influenza A (H5N1) viruses to oseltamivir.

Emergence and predominance of an H5N1 influenza variant in China.

Avian influenza A (H5N1) infection: targets and strategies for chemotherapeutic intervention.

Detection of influenza viruses resistant to neuraminidase inhibitors in global surveillance during the first 3 years of their use.

Evaluation of neuraminidase enzyme assays using different substrates to measure susceptibility of influenza virus clinical isolates to neuraminidase inhibitors: report of the neuraminidase inhibitor susceptibility network.

Susceptibility of highly pathogenic A(H5N1) avian influenza viruses to the neuraminidase inhibitors and adamantanes.

Efficacy of oseltamivir therapy in ferrets inoculated with different clades of H5N1 influenza virus

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10.3201/EID1309.070164

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9

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18252107

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2857286

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