Enzymatic properties of the neuraminidase of seasonal H1N1 influenza viruses provide insights for the emergence of natural resistance to oseltamivir.
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RNA virus genomics: a world of possibilitiesH1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural AnalysisFunctional and Structural Analysis of Influenza Virus Neuraminidase N3 Offers Further Insight into the Mechanisms of Oseltamivir ResistanceEnhanced mammalian transmissibility of seasonal influenza A/H1N1 viruses encoding an oseltamivir-resistant neuraminidaseThe short stalk length of highly pathogenic avian influenza H5N1 virus neuraminidase limits transmission of pandemic H1N1 virus in ferretsOseltamivir-resistant pandemic A/H1N1 virus is as virulent as its wild-type counterpart in mice and ferretsOseltamivir-resistant pandemic H1N1/2009 influenza virus possesses lower transmissibility and fitness in ferretsEnvironmental levels of the antiviral oseltamivir induce development of resistance mutation H274Y in influenza A/H1N1 virus in mallardsEvolutionary history and phylodynamics of influenza A and B neuraminidase (NA) genes inferred from large-scale sequence analysesDetection of oseltamivir-resistant pandemic influenza A(H1N1)pdm2009 in Brazil: can community transmission be ruled out?Coordinated Evolution of Influenza A Surface ProteinsIota-carrageenan is a potent inhibitor of influenza A virus infectionOseltamivir (Tamiflu(®)) in the environment, resistance development in influenza A viruses of dabbling ducks and the risk of transmission of an oseltamivir-resistant virus to humans - a reviewUsing high-throughput sequencing to leverage surveillance of genetic diversity and oseltamivir resistance: a pilot study during the 2009 influenza A(H1N1) pandemic.A conformational restriction in the influenza A virus neuraminidase binding site by R152 results in a combinational effect of I222T and H274Y on oseltamivir resistance.Oseltamivir-resistant influenza viruses A (H1N1), Norway, 2007-08Antiviral susceptibility of avian and swine influenza virus of the N1 neuraminidase subtype.Pandemic H1N1 2009 influenza virus with the H275Y oseltamivir resistance neuraminidase mutation shows a small compromise in enzyme activity and viral fitness.A computational-experimental approach identifies mutations that enhance surface expression of an oseltamivir-resistant influenza neuraminidase.The global spread of drug-resistant influenza.Oseltamivir in seasonal, pandemic, and avian influenza: a comprehensive review of 10-years clinical experience.Identification and epidemiology of severe respiratory disease due to novel swine-origin influenza A (H1N1) virus infection in Alberta.The 2008-2009 H1N1 influenza virus exhibits reduced susceptibility to antibody inhibition: Implications for the prevalence of oseltamivir resistant variant viruses.Efficient transmission of pandemic H1N1 influenza viruses with high-level oseltamivir resistanceFitness of neuraminidase inhibitor-resistant influenza A virusesIn vitro passaging of a pandemic H1N1/09 virus selects for viruses with neuraminidase mutations conferring high-level resistance to oseltamivir and peramivir, but not to zanamivir.Comparable fitness and transmissibility between oseltamivir-resistant pandemic 2009 and seasonal H1N1 influenza viruses with the H275Y neuraminidase mutation.The H275Y neuraminidase mutation of the pandemic A/H1N1 influenza virus lengthens the eclipse phase and reduces viral output of infected cells, potentially compromising fitness in ferrets.I223R mutation in influenza A(H1N1)pdm09 neuraminidase confers reduced susceptibility to oseltamivir and zanamivir and enhanced resistance with H275YSystematic identification of H274Y compensatory mutations in influenza A virus neuraminidase by high-throughput screening.Spatiotemporal circulation of influenza viruses in 5 African countries during 2008-2009: a collaborative study of the Institut Pasteur International Network.Consequences of resistance: in vitro fitness, in vivo infectivity, and transmissibility of oseltamivir-resistant influenza A viruses.Characterization of neuraminidase inhibitor-resistant influenza A(H1N1)pdm09 viruses isolated in four seasons during pandemic and post-pandemic periods in JapanA two-year survey of the oseltamivir-resistant influenza A(H1N1) virus in Yamagata, Japan and the clinical effectiveness of oseltamivir and zanamivirEvolution in health and medicine Sackler colloquium: The comparative genomics of viral emergence.Assessing the in vitro fitness of an oseltamivir-resistant seasonal A/H1N1 influenza strain using a mathematical modelReassortment and mutations associated with emergence and spread of oseltamivir-resistant seasonal influenza A/H1N1 viruses in 2005-2009.Competitive fitness of oseltamivir-sensitive and -resistant highly pathogenic H5N1 influenza viruses in a ferret model.Role of permissive neuraminidase mutations in influenza A/Brisbane/59/2007-like (H1N1) virusesPermissive secondary mutations enable the evolution of influenza oseltamivir resistance.
P2860
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P2860
Enzymatic properties of the neuraminidase of seasonal H1N1 influenza viruses provide insights for the emergence of natural resistance to oseltamivir.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Enzymatic properties of the ne ...... ral resistance to oseltamivir.
@ast
Enzymatic properties of the ne ...... ral resistance to oseltamivir.
@en
type
label
Enzymatic properties of the ne ...... ral resistance to oseltamivir.
@ast
Enzymatic properties of the ne ...... ral resistance to oseltamivir.
@en
prefLabel
Enzymatic properties of the ne ...... ral resistance to oseltamivir.
@ast
Enzymatic properties of the ne ...... ral resistance to oseltamivir.
@en
P2860
P50
P1433
P1476
Enzymatic properties of the ne ...... ral resistance to oseltamivir.
@en
P2093
Frédérique Cuvelier
Patricia Jeannin
P2860
P304
P356
10.1371/JOURNAL.PPAT.1000103
P577
2008-07-25T00:00:00Z