Membrane localization of insulin receptor substrate-2 (IRS-2) is associated with decreased overall survival in breast cancer
about
IRS1 is highly expressed in localized breast tumors and regulates the sensitivity of breast cancer cells to chemotherapy, while IRS2 is highly expressed in invasive breast tumorsInsulin receptor substrate 2-mediated phosphatidylinositol 3-kinase signaling selectively inhibits glycogen synthase kinase 3β to regulate aerobic glycolysis.Differential involvement of the microtubule cytoskeleton in insulin receptor substrate 1 (IRS-1) and IRS-2 signaling to AKT determines the response to microtubule disruption in breast carcinoma cells.Identification of a novel invasion-promoting region in Insulin Receptor Substrate 2 (IRS2).IRS2 mutations linked to invasion in pleomorphic invasive lobular carcinoma.
P2860
Membrane localization of insulin receptor substrate-2 (IRS-2) is associated with decreased overall survival in breast cancer
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Membrane localization of insul ...... rall survival in breast cancer
@ast
Membrane localization of insul ...... rall survival in breast cancer
@en
type
label
Membrane localization of insul ...... rall survival in breast cancer
@ast
Membrane localization of insul ...... rall survival in breast cancer
@en
prefLabel
Membrane localization of insul ...... rall survival in breast cancer
@ast
Membrane localization of insul ...... rall survival in breast cancer
@en
P2093
P2860
P1476
Membrane localization of insul ...... rall survival in breast cancer
@en
P2093
Ashraf Khan
Celina G Kleer
Chung-Cheng Hsieh
Jennifer L Clark
Karen Dresser
Leslie M Shaw
Michael Sabel
P2860
P2888
P304
P356
10.1007/S10549-011-1353-1
P407
P577
2011-01-22T00:00:00Z
P5875
P6179
1016116226