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Cardiac aging in mice and humans: the role of mitochondrial oxidative stress

Cardiac aging in mice and humans: the role of mitochondrial oxidative stress

http://www.wikidata.org/entity/Q33806910

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Vitamin C for treating atrial fibrillation Vitamin C for treating atrial fibrillation Fatty old hearts: role of cardiac lipotoxicity in age-related cardiomyopathy Geroscience approaches to increase healthspan and slow aging Interaction of Hydrogen Sulfide with Nitric Oxide in the Cardiovascular System Growth factors, nutrient signaling, and cardiovascular aging Age-related changes in brain support cells: Implications for stroke severity New insights into the role of mitochondrial dynamics and autophagy during oxidative stress and aging in the heart Mitochondria and cardiovascular aging Mitochondrial oxidative stress in aging and healthspan Is physical activity able to modify oxidative damage in cardiovascular aging?Quality control systems in cardiac aging Mitochondrial dysfunction in cardiac aging Mitochondria and oxidative stress in heart aging Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling The Role of Exercise in Cardiac Aging: From Physiology to Molecular Mechanisms 17β-Estradiol, aging, inflammation, and the stress response in the female heart Cardiac function of the naked mole-rat: ecophysiological responses to working underground Role of circulating factors in cardiac aging.Matrix metalloproteinase-28 deletion amplifies inflammatory and extracellular matrix responses to cardiac aging Rapamycin extends murine lifespan but has limited effects on aging.High-fat feeding-induced hyperinsulinemia increases cardiac glucose uptake and mitochondrial function despite peripheral insulin resistance.Chronic Endurance Exercise Impairs Cardiac Structure and Function in Middle-Aged Mice with Impaired Nrf2 Signaling.Heart failure with preserved ejection fraction: molecular pathways of the aging myocardium Inhibition of delta-6 desaturase reverses cardiolipin remodeling and prevents contractile dysfunction in the aged mouse heart without altering mitochondrial respiratory function.Physical exercise regulates p53 activity targeting SCO2 and increases mitochondrial COX biogenesis in cardiac muscle with age.A heart that beats for 500 years: age-related changes in cardiac proteasome activity, oxidative protein damage and expression of heat shock proteins, inflammatory factors, and mitochondrial complexes in Arctica islandica, the longest-living noncolon Longevity, aging and rapamycin.Cardioprotection and lifespan extension by the natural polyamine spermidine.The heart: mostly postmitotic or mostly premitotic? Myocyte cell cycle, senescence, and quiescence.mtDNA Mutations and Their Role in Aging, Diseases and Forensic Sciences Non-sirtuin histone deacetylases in the control of cardiac aging Linkage of cardiac gene expression profiles and ETS2 with lifespan variability in rats Getting to the heart of the matter: age-related changes in diastolic heart function in the longest-lived rodent, the naked mole rat.Cardiac aging: from molecular mechanisms to significance in human health and disease Aging might increase myocardial ischemia / reperfusion-induced apoptosis in humans and rats Contribution of impaired mitochondrial autophagy to cardiac aging: mechanisms and therapeutic opportunities.The intersection between aging and cardiovascular disease.Use of antiarrhythmic drugs in elderly patients Deletion of IGF-1 Receptors in Cardiomyocytes Attenuates Cardiac Aging in Male Mice.

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Cardiac aging in mice and humans: the role of mitochondrial oxidative stress

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J.TCM.2009.12.004

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Trends in Cardiovascular Medicine

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Cardiac aging in mice and humans: the role of mitochondrial oxidative stress

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Dao-Fu Dai

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Peter S Rabinovitch

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P2860

Premature ageing in mice expressing defective mitochondrial DNA polymerase

Evidence for cardiomyocyte renewal in humans

Disruption of the Ang II type 1 receptor promotes longevity in mice

Aging: a theory based on free radical and radiation chemistry

Mitochondria, oxidants, and aging

Extension of murine life span by overexpression of catalase targeted to mitochondria

Regulation of cardiac hypertrophy by intracellular signalling pathways

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

Adult cardiac stem cells are multipotent and support myocardial regeneration

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