Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein
about
Directed evolution generates a novel oncolytic virus for the treatment of colon cancerExpanded anticancer therapeutic window of hexon-modified oncolytic adenovirus.Chemical modification with high molecular weight polyethylene glycol reduces transduction of hepatocytes and increases efficacy of intravenously delivered oncolytic adenovirusInfection and killing of multiple myeloma by adenovirusesLinked tumor-selective virus replication and transgene expression from E3-containing oncolytic adenovirusesTissue-specific, tumor-selective, replication-competent adenovirus vector for cancer gene therapy.Replicating adenoviruses that target tumors with constitutive activation of the wnt signaling pathwayNonneurotropic adenovirus: a vector for gene transfer to the brain and gene therapy of neurological disordersReplication and virus-induced transcriptome of HAdV-5 in normal host cells versus cancer cells--differences of relevance for adenoviral oncolysis.Replication-selective oncolytic adenoviruses: virotherapy aimed at genetic targets in cancer.Replication-selective virotherapy for cancer: Biological principles, risk management and future directions.Intravascular adenoviral agents in cancer patients: lessons from clinical trials.Armed therapeutic viruses: strategies and challenges to arming oncolytic viruses with therapeutic genes.The oncolytic virotherapy treatment platform for cancer: unique biological and biosafety points to consider.Human adenovirus type 5 induces cell lysis through autophagy and autophagy-triggered caspase activityMutations within the ADP (E3-11.6K) protein alter processing and localization of ADP and the kinetics of cell lysis of adenovirus-infected cells.Increasing the efficacy of oncolytic adenovirus vectorsOncolytic adenovirus expressing interferon alpha in a syngeneic Syrian hamster model for the treatment of pancreatic cancer.Functions and mechanisms of action of the adenovirus E3 proteins.Oncolytic viral therapies.Replication-selective oncolytic viruses in the treatment of cancer.An acute toxicology study with INGN 007, an oncolytic adenovirus vector, in mice and permissive Syrian hamsters; comparisons with wild-type Ad5 and a replication-defective adenovirus vector.New pancreatic carcinoma model for studying oncolytic adenoviruses in the permissive Syrian hamster.Anticancer activity of oncolytic adenovirus vector armed with IFN-alpha and ADP is enhanced by pharmacologically controlled expression of TRAILINGN 007, an oncolytic adenovirus vector, replicates in Syrian hamsters but not mice: comparison of biodistribution studies.A fully replication-competent adenovirus vector with enhanced oncolytic propertiesIdentification of a new human adenovirus protein encoded by a novel late l-strand transcription unit.Oncolytic adenoviruses - selective retargeting to tumor cells.The effects of radiation on antitumor efficacy of an oncolytic adenovirus vector in the Syrian hamster modelThe role of cyclophosphamide in enhancing antitumor efficacy of an adenovirus oncolytic vector in subcutaneous Syrian hamster tumors.Reprogrammed viruses as cancer therapeutics: targeted, armed and shielded.Armed replicating adenoviruses for cancer virotherapy.Adenoviral vector-based strategies for cancer therapy.Down-regulation of multiple cell survival proteins in head and neck cancer cells by an apoptogenic mutant of adenovirus type 5.Characterization of human adenovirus serotypes 5, 6, 11, and 35 as anticancer agentsThe current state of head and neck cancer gene therapy.Oncolytic (replication-competent) adenoviruses as anticancer agents.CD46-mediated transduction of a species D adenovirus vaccine improves mucosal vaccine efficacy.Clinical development directions in oncolytic viral therapy.Oncolytic virotherapy
P2860
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P2860
Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein
description
2000 nî lūn-bûn
@nan
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Tumor-specific, replication-co ...... g the adenovirus death protein
@ast
Tumor-specific, replication-co ...... g the adenovirus death protein
@en
type
label
Tumor-specific, replication-co ...... g the adenovirus death protein
@ast
Tumor-specific, replication-co ...... g the adenovirus death protein
@en
prefLabel
Tumor-specific, replication-co ...... g the adenovirus death protein
@ast
Tumor-specific, replication-co ...... g the adenovirus death protein
@en
P2093
P2860
P1433
P1476
Tumor-specific, replication-co ...... g the adenovirus death protein
@en
P2093
P2860
P304
P356
10.1128/JVI.74.13.6147-6155.2000
P50
P577
2000-07-01T00:00:00Z