Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis.
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Adenovirus E1A proteins interact with the cellular YY1 transcription factorHomologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteinsp300/CREB binding protein-related protein p270 is a component of mammalian SWI/SNF complexesAcetyltransferases and tumour suppressionAdenovirus-mediated sensitization to the cytotoxic drugs docetaxel and mitoxantrone is dependent on regulatory domains in the E1ACR1 gene-regionp300 family members associate with the carboxyl terminus of simian virus 40 large tumor antigenAdenovirus E1A inhibits cardiac myocyte-specific gene expression through its amino terminusInduction of AP-1 DNA-binding activity and c-fos mRNA by the adenovirus 243R E1A protein and cyclic AMP requires domains necessary for transformation.Influenza A virus replication induces cell cycle arrest in G0/G1 phaseE1A promotes association between p300 and pRB in multimeric complexes required for normal biological activityIdentification of a novel E1A response element in the mouse c-fos promoter.Expression of the pRb-binding regions of E1A enables efficient transformation of primary epithelial cells by v-src.The early region 4 orf4 protein of human adenovirus type 5 induces p53-independent cell death by apoptosis.Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death proteinInduction of transformation and p53-dependent apoptosis by adenovirus type 5 E4orf6/7 cDNA.Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complexTissue-specific, tumor-selective, replication-competent adenovirus vector for cancer gene therapy.A novel function of adenovirus E1A is required to overcome growth arrest by the CDK2 inhibitor p27(Kip1).A cancer-specific transcriptional signature in human neoplasia.Murine coronavirus replication induces cell cycle arrest in G0/G1 phase.Adenovirus E1A N-terminal amino acid sequence requirements for repression of transcription in vitro and in vivo correlate with those required for E1A interference with TBP-TATA complex formation.Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus.Plant orthologs of p300/CBP: conservation of a core domain in metazoan p300/CBP acetyltransferase-related proteins.The CtBP binding domain in the adenovirus E1A protein controls CR1-dependent transactivation.The high-risk HPV16 E7 oncoprotein mediates interaction between the transcriptional coactivator CBP and the retinoblastoma protein pRb.Enterovirus 71 mediates cell cycle arrest in S phase through non-structural protein 3D.Repression of c-Myc and inhibition of G1 exit in cells conditionally overexpressing p300 that is not dependent on its histone acetyltransferase activityAdenovirus type 5 exerts genome-wide control over cellular programs governing proliferation, quiescence, and survival.Induction of susceptibility to tumor necrosis factor by E1A is dependent on binding to either p300 or p105-Rb and induction of DNA synthesisCharacterization of monoclonal antibodies raised against p300: both p300 and CBP are present in intracellular TBP complexes.Accumulation of p53 induced by the adenovirus E1A protein requires regions involved in the stimulation of DNA synthesis.Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells.Protein domains connect cell cycle stimulation directly to initiation of DNA replication.Cells differentiating into neuroectoderm undergo apoptosis in the absence of functional retinoblastoma family proteins.Induction of DNA synthesis and apoptosis in cardiac myocytes by E1A oncoprotein.Viruses - seeking and destroying the tumor program.Adenovirus E1A proteins are closely associated with chromatin in productively infected and transformed cells.The virtue of just enough stress: a molecular model.Suppression of mutations in two Saccharomyces cerevisiae genes by the adenovirus E1A protein.Roles for the coactivators CBP and p300 and the APC/C E3 ubiquitin ligase in E1A-dependent cell transformation.
P2860
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P2860
Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis.
description
1990 nî lūn-bûn
@nan
1990 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Retinoblastoma growth suppress ...... gulate cellular DNA synthesis.
@ast
Retinoblastoma growth suppress ...... gulate cellular DNA synthesis.
@en
type
label
Retinoblastoma growth suppress ...... gulate cellular DNA synthesis.
@ast
Retinoblastoma growth suppress ...... gulate cellular DNA synthesis.
@en
prefLabel
Retinoblastoma growth suppress ...... gulate cellular DNA synthesis.
@ast
Retinoblastoma growth suppress ...... gulate cellular DNA synthesis.
@en
P2093
P2860
P356
P1476
Retinoblastoma growth suppress ...... gulate cellular DNA synthesis.
@en
P2093
P2860
P304
P356
10.1073/PNAS.87.15.5883
P407
P577
1990-08-01T00:00:00Z