Antiviral activity of the interferon-induced cellular protein BST-2/tetherin. - Wikidata - wikimedia - TriplyDB

Antiviral activity of the interferon-induced cellular protein BST-2/tetherin.

Antiviral activity of the interferon-induced cellular protein BST-2/tetherin.

http://www.wikidata.org/entity/Q33807551

about

The role of BST-2/Tetherin in host protection and disease manifestation Structural insight into the mechanisms of enveloped virus tethering by tetherin HSV-2 glycoprotein gD targets the CC domain of tetherin and promotes tetherin degradation via lysosomal pathway Patterns of HIV-1 protein interaction identify perturbed host-cellular subsystems Molecular evolution of the primate antiviral restriction factor tetherin Characterization of E3 ligases involved in lysosomal sorting of the HIV-1 restriction factor BST2.Viral and host proteins that modulate filovirus budding Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu.Tetherin promotes the innate and adaptive cell-mediated immune response against retrovirus infection in vivo.Expression analysis of LEDGF/p75, APOBEC3G, TRIM5alpha, and tetherin in a Senegalese cohort of HIV-1-exposed seronegative individuals.Defining molecular signature of pro-immunogenic radiotherapy targets in human prostate cancer cells.Identification of amino acids in the human tetherin transmembrane domain responsible for HIV-1 Vpu interaction and susceptibility.Vpu binds directly to tetherin and displaces it from nascent virions.APOBEC3G polymorphism as a selective barrier to cross-species transmission and emergence of pathogenic SIV and AIDS in a primate host.Regulation of Interferon-Stimulated Gene BST2 by a lncRNA Transcribed from a Shared Bidirectional Promoter.TRIM22 inhibits HIV-1 transcription independently of its E3 ubiquitin ligase activity, Tat, and NF-kappaB-responsive long terminal repeat elements.Misdirection of membrane trafficking by HIV-1 Vpu and Nef: Keys to viral virulence and persistence.Upregulation of BST-2/Tetherin by HIV infection in vivo.Twelve-Month Antiretroviral Therapy Suppresses Plasma and Genital Viral Loads but Fails to Alter Genital Levels of Cytokines, in a Cohort of HIV-Infected Rwandan Women.Screening low-frequency SNPS from genome-wide association study reveals a new risk allele for progression to AIDS A small molecule compound IMB-LA inhibits HIV-1 infection by preventing viral Vpu from antagonizing the host restriction factor BST-2.IL-27 increases BST-2 expression in human monocytes and T cells independently of type I IFN.Immunogenetics: Genome-Wide Association of Non-Progressive HIV and Viral Load Control: HLA Genes and Beyond.Toll-like receptor 7 inhibits early acute retroviral infection through rapid lymphocyte responses The Evolutionary Histories of Antiretroviral Proteins SERINC3 and SERINC5 Do Not Support an Evolutionary Arms Race in Primates.Functional antagonism of rhesus macaque and chimpanzee BST-2 by HIV-1 Vpu is mediated by cytoplasmic domain interactions.Single Amino Acid Substitution N659D in HIV-2 Envelope Glycoprotein (Env) Impairs Viral Release and Hampers BST-2 Antagonism.The Significance of Interferon-γ in HIV-1 Pathogenesis, Therapy, and Prophylaxis.Tetherin has negligible activity in restricting hepatitis C virus in hepatocytes.Evidence for the innate immune response as a correlate of protection in human immunodeficiency virus (HIV)-1 highly exposed seronegative subjects (HESN).Retroviral restriction and dependency factors in primates and carnivores.The type I interferon response during viral infections: a "SWOT" analysis.Species tropism of HIV-1 modulated by viral accessory proteins.Feline immunodeficiency virus envelope glycoproteins antagonize tetherin through a distinctive mechanism that requires virion incorporation.Innate immunity against HIV-1 infection.On the general theory of the origins of retroviruses.The Nuclear DNA Sensor IFI16 Acts as a Restriction Factor for Human Papillomavirus Replication through Epigenetic Modifications of the Viral Promoters.The roles of ebolavirus glycoproteins in viral pathogenesis.Identification of novel key amino acids at the interface of the transmembrane domains of human BST-2 and HIV-1 Vpu Two retroviruses packaged in one cell line can combined inhibit the replication of HIV-1 in TZM-bl cells.

P2860

Q26752737-8ABCAAEC-DD1E-4992-AED8-4078C8CAA659 Q27664987-75AE48EC-30FD-4917-B832-D45969E4075F Q28595739-FDE92338-DA7A-4A55-ADDB-3AC68663ECCA Q33649755-32326BB6-59C8-4784-8F84-260BFB887CE4 Q33650914-90C8F98B-038C-4FE2-BC41-CA0F42F0F7DF Q33743176-929DF482-888A-4AD0-940C-9587113D1A88 Q34070413-47894BC1-316B-4429-B6AE-DBF118FA5ABC Q34146128-702BA82C-0355-4193-9BB3-549D4222E9F4 Q34180302-D81CB655-25EC-4F4F-A943-5FDB19642920 Q34221798-035B5836-0CBC-4F5F-811A-3ACF74ED4A02 Q34438000-59FABE6E-5E63-446C-A73D-9595D8A0B39C Q34485169-588E302C-833B-4798-9A1E-6948C5D4E152 Q34697856-4D1BC446-AA0A-4C8A-B911-FEE8DE6668F8 Q35008780-9793606C-0118-4C18-BDC7-B9607B831C68 Q35030956-93B12DED-D925-4846-9053-D86CD5E72EED Q35076765-F4AF4E0C-0333-4909-83AD-76026B2A32B1 Q35214569-75C6BF65-15DE-49DF-84FF-7DF485F22CBD Q35275193-D5B03110-60DC-4EC3-9047-1B06E68B022D Q35641764-8D7B6C8A-83AE-41D6-AC6F-0BC36BE81E0C Q36068205-C5980AFF-E842-48F9-B9CF-E46AD6423042 Q36376142-CE43B971-C54C-4581-8998-1D32FF6E28B5 Q36463634-3BCD12CE-2A50-4AE6-B09A-B3475EAEB9A7 Q36876711-F13603C4-8656-42F4-BC75-E8AFC8DB04F2 Q36978940-68BE6C4E-6B32-439C-8426-E59E3B31DE2C Q37224846-C9C22CFD-6DC1-449B-8239-94EE9BA363F5 Q37336745-1BA6E32F-4C21-4EB5-B0F6-E72043A7FC42 Q37378819-60993FEA-1329-4BB0-83C8-1315D55DB9F6 Q37466832-D108D3E2-25AC-4DA9-A445-518AFD66A8F3 Q37607851-AB0BFD00-677C-4BAE-935F-DD5ACC920041 Q37854081-AB93ABA3-648A-458B-805F-BEE846991FAF Q37895742-5FA6C271-FD64-4A72-A63E-03E8DD035E55 Q37942501-5D5694F3-9C1B-4025-AEAA-D8EFF33B6F75 Q38031461-D03D467E-4FFC-4CD3-B759-464CA382EBF4 Q38326209-CDB1CBBD-444E-4847-AEF0-2C1E2144658D Q38491184-DC28C3E1-1BBF-4503-B618-ED4749D70461 Q38872947-3CC6CC72-5B35-4E61-A43D-E99176F1BB06 Q38875175-DC510D1C-6518-4C8A-987A-19E81404A36A Q39010678-2EEB7329-2412-4C47-82BC-E90B2A1E6DE3 Q39114721-7FEC8BC8-409D-4987-BF56-0000B7A04467 Q39236886-634A0109-64CA-4CC8-A707-F60770D471B6

P2860

Antiviral activity of the interferon-induced cellular protein BST-2/tetherin.

http://www.wikidata.org/entity/Q33807551

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Antiviral activity of the interferon-induced cellular protein BST-2/tetherin.

@ast

Antiviral activity of the interferon-induced cellular protein BST-2/tetherin.

@en

type

label

Antiviral activity of the interferon-induced cellular protein BST-2/tetherin.

@ast

Antiviral activity of the interferon-induced cellular protein BST-2/tetherin.

@en

altLabel

Antiviral activity of the interferon-induced cellular protein BST-2/tetherin

@en

prefLabel

Antiviral activity of the interferon-induced cellular protein BST-2/tetherin.

@ast

Antiviral activity of the interferon-induced cellular protein BST-2/tetherin.

@en

P1433

Q33807551-1AEA5763-0BC3-409E-B936-060F87837A59

P1476

Q33807551-AE573436-2D9C-46CD-96F2-5E8B1E7524C6

P2093

Q33807551-6BD67F41-095D-4F7E-9308-CA8F19AB83F9

Q33807551-9386BD5F-AE25-4961-807A-4DA00B28E54C

Q33807551-A11FCB7E-91C1-48C0-90EC-AA2214F0DA15

Q33807551-DD898CB5-759B-4369-B07A-6C080A86925F

P2860

Q33807551-01DA3317-26C4-455E-B98C-EB0173180B9E

Q33807551-0373CFA1-E24E-4037-9DA2-3073F2E6254D

Q33807551-0C922BB8-A9BD-4546-83DC-4E2D41592FC3

Q33807551-0F2E3B44-23E1-44AE-9EBF-7C4C34F35B5B

Q33807551-1015BFD8-56B4-4278-9C3F-55C211D566DD

Q33807551-18264E9B-3688-4CE7-AB73-F15277FB8E7A

Q33807551-193DD707-80EB-49AF-960C-B4707AE6F3AE

Q33807551-222745BA-7D94-43AA-AF80-9357BC826C86

Q33807551-22B4A747-20E4-498C-88B2-856B09F7FD85

Q33807551-2512E83B-65C3-4CBB-A20D-DB295394E3D7

P304

Q33807551-A79042B1-9C56-4C9C-880B-FFF343170733

P31

Q33807551-9B43E72B-80D0-4E33-8BF7-5FF5B37B2B41

P356

Q33807551-54A430C6-36E2-4109-860A-8561998C2BFC

P407

Q33807551-75607F32-4A2B-4A64-A579-1BBDA6EC6C48

P433

Q33807551-0CC97175-4460-4F57-97DC-C3851C7EFDED

P478

Q33807551-E5D9F773-3919-437E-8C69-64160F220A0A

P577

Q33807551-DFF9E6F4-C518-4F14-A1DC-EFFE10BE0C7C

P5875

Q33807551-67DCFC89-B0D5-4BB4-BFD5-E228431B160C

P698

Q33807551-9D6D5020-86E8-4A5C-A6F1-DE398045023A

P921

Q33807551-5D386E1D-E26E-4022-A7EA-15D862BFF895

Q33807551-6CCCAEA2-44E4-4B52-BB03-5A6DEF091C91

Q33807551-B520F100-2603-4167-8BCB-FDAF8FF47EB6

P932

Q33807551-6B9929DD-5343-486B-9BF7-B4650537A192

P356

P1433

AIDS Research and Human Retroviruses

P1476

Antiviral activity of the interferon-induced cellular protein BST-2/tetherin.

@en

P2093

Andrey Tokarev

http://www.w3.org/2001/XMLSchema#string

John Guatelli

http://www.w3.org/2001/XMLSchema#string

Kathleen Fitzpatrick

http://www.w3.org/2001/XMLSchema#string

Mark Skasko

http://www.w3.org/2001/XMLSchema#string

P2860

HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation

The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu

Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2

HIV enters cells via endocytosis and dynamin-dependent fusion with endosomes

Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction

Broad-spectrum inhibition of retroviral and filoviral particle release by tetherin

Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses

Vpu directs the degradation of the human immunodeficiency virus restriction factor BST-2/Tetherin via a {beta}TrCP-dependent mechanism

HIV-1 accessory protein Vpu internalizes cell-surface BST-2/tetherin through transmembrane interactions leading to lysosomes

Molecular mechanism of BST2/tetherin downregulation by K5/MIR2 of Kaposi's sarcoma-associated herpesvirus

P304

1197-1210

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1089/AID.2009.0253

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

25

http://www.w3.org/2001/XMLSchema#string

P577

2009-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

40022654

http://www.w3.org/2001/XMLSchema#string

P698

19929170

http://www.w3.org/2001/XMLSchema#string

P921

infectious disease

P932

2858902

http://www.w3.org/2001/XMLSchema#string