Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligase - Wikidata - wikimedia - TriplyDB

Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligase

Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligase

http://www.wikidata.org/entity/Q33807681

about

A HECT domain E3 enzyme assembles novel polyubiquitin chains Association of E6AP (UBE3A) with human papillomavirus type 11 E6 protein.E6AP ubiquitin ligase mediates ubiquitylation and degradation of hepatitis C virus core protein Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes Differential localization of HPV16 E6 splice products with E6-associated protein.Solution Structure Analysis of the HPV16 E6 Oncoprotein Reveals a Self-Association Mechanism Required for E6-Mediated Degradation of p53 The ubiquitin-proteasome pathway and proteasome inhibitors Papillomavirus E6 oncoproteins.HECT E3s and human disease.Nitrosative stress induces peroxiredoxin 1 ubiquitination during ischemic insult via E6AP activation in endothelial cells both in vitro and in vivo.Growth suppression induced by downregulation of E6-AP expression in human papillomavirus-positive cancer cell lines depends on p53 Beta-HPV 5 and 8 E6 promote p300 degradation by blocking AKT/p300 association Pathogenesis of human papillomaviruses in differentiating epithelia.A mutant of human papillomavirus type 16 E6 deficient in binding alpha-helix partners displays reduced oncogenic potential in vivo.The human papillomavirus E6 protein and its contribution to malignant progression.Pitx2a binds to human papillomavirus type 18 E6 protein and inhibits E6-mediated P53 degradation in HeLa cells.Proteomic profiling in Drosophila reveals potential Dube3a regulation of the actin cytoskeleton and neuronal homeostasis Regulation of DNA damage response pathways by the cullin-RING ubiquitin ligases Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2 Distinct phenotypes distinguish the molecular classes of Angelman syndrome E6AP-dependent degradation of DLG4/PSD95 by high-risk human papillomavirus type 18 E6 protein.PATJ, a tight junction-associated PDZ protein, is a novel degradation target of high-risk human papillomavirus E6 and the alternatively spliced isoform 18 E6 Angelman Syndrome.Role of ubiquitin and the HPV E6 oncoprotein in E6AP-mediated ubiquitination Identification of the in vivo role of a viral bcl-2 E6-associated protein (E6-AP) is a dual function coactivator of steroid hormone receptors.The active form of E6-associated protein (E6AP)/UBE3A ubiquitin ligase is an oligomer.Molecular mechanisms of viral immune evasion proteins to inhibit MHC class I antigen processing and presentation.Molecular mechanisms of IFN-gamma to up-regulate MHC class I antigen processing and presentation.Macrophages kill human papillomavirus type 16 E6-expressing tumor cells by tumor necrosis factor alpha- and nitric oxide-dependent mechanisms.Navigating the nucleotide excision repair threshold.Ubiquitination of E3 ligases: self-regulation of the ubiquitin system via proteolytic and non-proteolytic mechanisms.COP9 signalosome function in the DDR.Ataxin-3 and its e3 partners: implications for machado-joseph disease.E6AP in the brain: one protein, dual function, multiple diseases.The E6 oncoproteins from human betapapillomaviruses differentially activate telomerase through an E6AP-dependent mechanism and prolong the lifespan of primary keratinocytes.A ubiquitin-interacting motif (UIM) is essential for Eps15 and Eps15R ubiquitination.Mutagenic Potential ofBos taurus Papillomavirus Type 1 E6 Recombinant Protein: First Description.Human papillomavirus 16 E6 is associated with the nuclear matrix of esophageal carcinoma cells

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P2860

Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligase

http://www.wikidata.org/entity/Q33807681

description

2000 nî lūn-bûn

@nan

2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2000年の論文

@ja

2000年論文

@yue

2000年論文

@zh-hant

2000年論文

@zh-hk

2000年論文

@zh-mo

2000年論文

@zh-tw

2000年论文

@wuu

name

Human papillomavirus type 16 E ...... E6AP ubiquitin-protein ligase

@ast

Human papillomavirus type 16 E ...... E6AP ubiquitin-protein ligase

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type

label

Human papillomavirus type 16 E ...... E6AP ubiquitin-protein ligase

@ast

Human papillomavirus type 16 E ...... E6AP ubiquitin-protein ligase

@en

prefLabel

Human papillomavirus type 16 E ...... E6AP ubiquitin-protein ligase

@ast

Human papillomavirus type 16 E ...... E6AP ubiquitin-protein ligase

@en

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P356

JVI.74.14.6408-6417.2000

P1433

Journal of Virology

P1476

Human papillomavirus type 16 E ...... E6AP ubiquitin-protein ligase

@en

P2093

A L Talis

http://www.w3.org/2001/XMLSchema#string

J M Huibregtse

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P M Howley

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S L Beaudenon

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W H Kao

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P2860

Two human homologs of Rad23 are functionally interchangeable in complex formation and stimulation of XPC repair activity

Association of Bovine Papillomavirus Type 1 E6 oncoprotein with the focal adhesion protein paxillin through a conserved protein interaction motif

Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23

A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5

Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53

Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity

Cloning and characterization of hdlg: the human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1

The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation

P304

6408-6417

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scholarly article

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10.1128/JVI.74.14.6408-6417.2000

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14

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74

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2000-07-01T00:00:00Z

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12453465

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10864652

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P921

protein ubiquitination

P932

112148

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