Twenty years of p53 research: structural and functional aspects of the p53 protein.
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Expression of full-length p53 and its isoform Deltap53 in breast carcinomas in relation to mutation status and clinical parametersZAC, LIT1 (KCNQ1OT1) and p57KIP2 (CDKN1C) are in an imprinted gene network that may play a role in Beckwith-Wiedemann syndrome.Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domainsPhysical interaction and mutual transrepression between CCAAT/enhancer-binding protein beta and the p53 tumor suppressorStress-dependent nucleolin mobilization mediated by p53-nucleolin complex formationGlobal genome repair is required to activate KIN17, a UVC-responsive gene involved in DNA replication.AMF1 (GPS2) modulates p53 transactivationRegulation of RelA (p65) function by the large subunit of replication factor CChaga mushroom (Inonotus obliquus) induces G0/G1 arrest and apoptosis in human hepatoma HepG2 cellsThe role of circulating anti-p53 antibodies in patients with advanced non-small cell lung cancer and their correlation to clinical parameters and survivalMolecular characterizations of glioblastoma, targeted therapy, and clinical results to dateDiversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairsA Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in CardiomyocytesCovalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motifEnhancement of p53-dependent gene activation by the transcriptional coactivator Zac1A P53 target gene, PIG11, contributes to chemosensitivity of cells to arsenic trioxideConcentration-dependent, size-independent toxicity of citrate capped AuNPs in Drosophila melanogasterLack of the matricellular protein SPARC (secreted protein, acidic and rich in cysteine) attenuates liver fibrogenesis in miceScotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membraneModulation of the disordered conformational ensembles of the p53 transactivation domain by cancer-associated mutationsDiabetes-induced oxidative DNA damage alters p53-p21CIP1/Waf1 signaling in the rat testisp53-dependent S-phase damage checkpoint and pronuclear cross talk in mouse zygotes with X-irradiated sperm.p53 binds the nuclear matrix in normal cells: binding involves the proline-rich domain of p53 and increases following genotoxic stress.Associations between p53 overexpression and multiple measures of clinical outcome in high-risk, early stage or suboptimally-resected, advanced stage epithelial ovarian cancers A Gynecologic Oncology Group study.Integrating mutation data and structural analysis of the TP53 tumor-suppressor protein.Factors governing loss and rescue of DNA binding upon single and double mutations in the p53 core domain.DNA repair in Drosophila: insights from the Drosophila genome sequence.Mutation of p53 and consecutive selective drug resistance in B-CLL occurs as a consequence of prior DNA-damaging chemotherapy.Tumor protein 53 mutations are enriched in diffuse large B-cell lymphoma with irregular CD19 marker expression.Synthesis, characterization and antitumor activity of Ln(III) complexes with hydrazone Schiff base derived from 2-acetylpyridine and isonicotinohydrazonePhenotypic and in vivo functional characterization of immortalized human fetal liver cells.The K-bZIP protein from Kaposi's sarcoma-associated herpesvirus interacts with p53 and represses its transcriptional activity.Hepatitis C virus NS5A physically associates with p53 and regulates p21/waf1 gene expression in a p53-dependent mannerViral interferon regulatory factor 1 of Kaposi's sarcoma-associated herpesvirus binds to p53 and represses p53-dependent transcription and apoptosis.EEF1A2 inactivates p53 by way of PI3K/AKT/mTOR-dependent stabilization of MDM4 in hepatocellular carcinoma.Phytoestrogens and prevention of breast cancer: The contentious debateMutations in APC, Kirsten-ras, and p53--alternative genetic pathways to colorectal cancer.The role of death-associated protein 3 in apoptosis, anoikis and human cancerProteasomal degradation of p53 by human papillomavirus E6 oncoprotein relies on the structural integrity of p53 core domain.Strategies for manipulating the p53 pathway in the treatment of human cancer.
P2860
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P2860
Twenty years of p53 research: structural and functional aspects of the p53 protein.
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Twenty years of p53 research: structural and functional aspects of the p53 protein.
@ast
Twenty years of p53 research: structural and functional aspects of the p53 protein.
@en
type
label
Twenty years of p53 research: structural and functional aspects of the p53 protein.
@ast
Twenty years of p53 research: structural and functional aspects of the p53 protein.
@en
prefLabel
Twenty years of p53 research: structural and functional aspects of the p53 protein.
@ast
Twenty years of p53 research: structural and functional aspects of the p53 protein.
@en
P356
P1433
P1476
Twenty years of p53 research: structural and functional aspects of the p53 protein.
@en
P2888
P304
P356
10.1038/SJ.ONC.1203285
P407
P577
1999-12-01T00:00:00Z
P5875
P6179
1026171968