Wild-type and YMDD mutant murine leukemia virus reverse transcriptases are resistant to 2',3'-dideoxy-3'-thiacytidine - Wikidata - wikimedia - TriplyDB

Wild-type and YMDD mutant murine leukemia virus reverse transcriptases are resistant to 2',3'-dideoxy-3'-thiacytidine

Wild-type and YMDD mutant murine leukemia virus reverse transcriptases are resistant to 2',3'-dideoxy-3'-thiacytidine

http://www.wikidata.org/entity/Q33808236

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Fidelity of Nucleotide Incorporation by the RNA-Dependent RNA Polymerase from Poliovirus.YADD mutants of human immunodeficiency virus type 1 and Moloney murine leukemia virus reverse transcriptase are resistant to lamivudine triphosphate (3TCTP) in vitro.Susceptibility of the human retrovirus XMRV to antiretroviral inhibitors.Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision.Apparent defects in processive DNA synthesis, strand transfer, and primer elongation of Met-184 mutants of HIV-1 reverse transcriptase derive solely from a dNTP utilization defect.Azido-containing diketo acid derivatives inhibit human immunodeficiency virus type 1 integrase in vivo and influence the frequency of deletions at two-long-terminal-repeat-circle junctions.Lamivudine resistance in human T-cell leukemia virus type 1 may be due to a polymorphism at codon 118 (V-->I) of the reverse transcriptase.

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Wild-type and YMDD mutant murine leukemia virus reverse transcriptases are resistant to 2',3'-dideoxy-3'-thiacytidine

http://www.wikidata.org/entity/Q33808236

description

2000 nî lūn-bûn

@nan

2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի հուլիսին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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name

Wild-type and YMDD mutant muri ...... 2',3'-dideoxy-3'-thiacytidine

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Wild-type and YMDD mutant muri ...... 2',3'-dideoxy-3'-thiacytidine

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Wild-type and YMDD mutant muri ...... 2',3'-dideoxy-3'-thiacytidine

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Wild-type and YMDD mutant muri ...... 2',3'-dideoxy-3'-thiacytidine

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Wild-type and YMDD mutant muri ...... 2',3'-dideoxy-3'-thiacytidine

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Wild-type and YMDD mutant muri ...... 2',3'-dideoxy-3'-thiacytidine

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P356

JVI.74.14.6669-6674.2000

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Journal of Virology

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Wild-type and YMDD mutant muri ...... 2',3'-dideoxy-3'-thiacytidine

@en

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E K Halvas

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E O Freed

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E S Svarovskaia

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V K Pathak

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P2860

A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation

Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids

Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase

Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution: implications of conformational changes for polymerization and inhibition mechanisms

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

(-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro

The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

Site-specific mutagenesis of AIDS virus reverse transcriptase

High-level resistance to (-) enantiomeric 2'-deoxy-3'-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase

Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine

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6669-6674

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10.1128/JVI.74.14.6669-6674.2000

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14

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74

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2000-07-01T00:00:00Z

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