Structural determinants of murine leukemia virus reverse transcriptase that affect the frequency of template switching
about
Thermostable DNA polymerase from a viral metagenome is a potent RT-PCR enzymeAnalysis of transcribed human endogenous retrovirus W env loci clarifies the origin of multiple sclerosis-associated retrovirus env sequencesAccurately measuring recombination between closely related HIV-1 genomesEffects of homology length in the repeat region on minus-strand DNA transfer and retroviral replication.Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: balance between RNase H activity and nucleotide excisionMechanism analysis indicates that recombination events in HIV-1 initiate and complete over short distances, explaining why recombination frequencies are similar in different sections of the genomeDynamic copy choice: steady state between murine leukemia virus polymerase and polymerase-dependent RNase H activity determines frequency of in vivo template switching.Y586F mutation in murine leukemia virus reverse transcriptase decreases fidelity of DNA synthesis in regions associated with adenine-thymine tracts.Retroviral vectors for analysis of viral mutagenesis and recombination.Zinc finger domain of murine leukemia virus nucleocapsid protein enhances the rate of viral DNA synthesis in vivo.Pausing during reverse transcription increases the rate of retroviral recombinationFlaviviral RNAs: weapons and targets in the war between virus and host.Mechanisms and factors that influence high frequency retroviral recombinationMutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistanceExpression pattern analysis of transcribed HERV sequences is complicated by ex vivo recombination.Mutations in human immunodeficiency virus type 1 RNase H primer grip enhance 3'-azido-3'-deoxythymidine resistance.Retrovirus reverse transcriptases containing a modified YXDD motif.Antiretroviral drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase increase template-switching frequency.Apparent defects in processive DNA synthesis, strand transfer, and primer elongation of Met-184 mutants of HIV-1 reverse transcriptase derive solely from a dNTP utilization defect.Longitudinal analysis of intra-host simian immunodeficiency virus recombination in varied tissues of the rhesus macaque model for neuroAIDS.The remarkable frequency of human immunodeficiency virus type 1 genetic recombinationDynamics of HIV-1 recombination in its natural target cells.Host SAMHD1 protein promotes HIV-1 recombination in macrophages.Identifying recombination hot spots in the HIV-1 genome.Mutations in the RNase H primer grip domain of murine leukemia virus reverse transcriptase decrease efficiency and accuracy of plus-strand DNA transfer.Genomic stability of murine leukemia viruses containing insertions at the Env-3' untranslated region boundary.RNase H activity is required for high-frequency repeat deletion during Moloney murine leukemia virus replication.Template dimerization promotes an acceptor invasion-induced transfer mechanism during human immunodeficiency virus type 1 minus-strand synthesis.Altered error specificity of RNase H-deficient HIV-1 reverse transcriptases during DNA-dependent DNA synthesis.Hairpin-induced tRNA-mediated (HITME) recombination in HIV-1.Dissection of a circumscribed recombination hot spot in HIV-1 after a single infectious cycle.An RNA secondary structure bias for non-homologous reverse transcriptase-mediated deletions in vivoInsights into the multiple roles of pausing in HIV-1 reverse transcriptase-promoted strand transfers.Evidence that HIV-1 reverse transcriptase employs the DNA 3' end-directed primary/secondary RNase H cleavage mechanism during synthesis and strand transfer.
P2860
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P2860
Structural determinants of murine leukemia virus reverse transcriptase that affect the frequency of template switching
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Structural determinants of mur ...... requency of template switching
@ast
Structural determinants of mur ...... requency of template switching
@en
type
label
Structural determinants of mur ...... requency of template switching
@ast
Structural determinants of mur ...... requency of template switching
@en
prefLabel
Structural determinants of mur ...... requency of template switching
@ast
Structural determinants of mur ...... requency of template switching
@en
P2093
P2860
P1433
P1476
Structural determinants of mur ...... requency of template switching
@en
P2093
E S Svarovskaia
K A Delviks
P2860
P304
P356
10.1128/JVI.74.15.7171-7178.2000
P577
2000-08-01T00:00:00Z