Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair - Wikidata - wikimedia - TriplyDB

Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair

Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair

http://www.wikidata.org/entity/Q33818854

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Molecular regulation of telomerase activity in aging RecQ helicases in DNA double strand break repair and telomere maintenance.Evidence that the histone methyltransferase Dot1 mediates global genomic repair by methylating histone H3 on lysine 79.Telomeres shorten in response to oxidative stress in mouse skeletal muscle fibers Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis.Clustered and genome-wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitness Telomere proteins POT1, TRF1 and TRF2 augment long-patch base excision repair in vitro.Unravelling UVA-induced mutagenesis.Physical activity and telomere biology: exploring the link with aging-related disease prevention.Single-molecule analysis of thymine dimer-containing G-quadruplexes formed from the human telomere sequence.Defective repair of oxidative base lesions by the DNA glycosylase Nth1 associates with multiple telomere defects.Telomere maintenance genes SIRT1 and XRCC6 impact age-related decline in telomere length but only SIRT1 is associated with human longevity.Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts.Mechanisms of dysfunction in senescent pulmonary endothelium.Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.Mitochondrial dynamics and autophagy aid in removal of persistent mitochondrial DNA damage in Caenorhabditis elegans.Influence of a pre-stimulation with chronic low-dose UVB on stress response mechanisms in human skin fibroblasts Clusters of Multiple Mutations: Incidence and Molecular Mechanisms Constitutive expression of human telomerase enhances the proliferation potential of human mesenchymal stem cells.UVC-induced mitochondrial degradation via autophagy correlates with mtDNA damage removal in primary human fibroblasts.Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation High-resolution characterization of CPD hotspot formation in human fibroblasts.Never-ageing cellular senescence Photoinduced damage to cellular DNA: direct and photosensitized reactions.DNA Methylation Changes during In Vitro Propagation of Human Mesenchymal Stem Cells: Implications for Their Genomic Stability?DNA excision repair at telomeres.Repair of UV-induced DNA lesions in natural Saccharomyces cerevisiae telomeres is moderated by Sir2 and Sir3, and inhibited by yKu-Sir4 interaction.Polymerase η suppresses telomere defects induced by DNA damaging agents Convergence of The Nobel Fields of Telomere Biology and DNA Repair.Excitotoxic and Radiation Stress Increase TERT Levels in the Mitochondria and Cytosol of Cerebellar Purkinje Neurons.Cytoskeletal remodeling and regulation of cell fate in the hypertensive neonatal pulmonary artery in response to stress.The effects of UV emission from compact fluorescent light exposure on human dermal fibroblasts and keratinocytes in vitro.Blood micronutrients and DNA damage in children.Characterization of Senescence of Culture-expanded Human Adipose-derived Mesenchymal Stem Cells Conformational and electronic effects on the formation of anti cyclobutane pyrimidine dimers in G-quadruplex structures.Nucleotide Excision Repair: From Neurodegeneration to Cancer.Electronic Excitations in G-quadruplexes Formed by the Human Telomeric Sequence: A Time-Resolved Fluorescence Study.Telomere length is regulated by FGF-2 in human embryonic stem cells and affects the life span of its differentiated progenies.Contribution of Sp1 to Telomerase Expression and Activity in Skin Keratinocytes Cultured With a Feeder Layer.Human skin fibroblast telomeres are shortened after ultraviolet irradiation.

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P2860

Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair

http://www.wikidata.org/entity/Q33818854

description

2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair

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Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair

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Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair

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Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair

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Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair

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Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair

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JOURNAL.PGEN.1000926

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Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair

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Douglas E Brash

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Patrick J Rochette

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P2860

Bipyrimidine Photoproducts Rather than Oxidative Lesions Are the Main Type of DNA Damage Involved in the Genotoxic Effect of Solar UVA Radiation †

Telomere measurement by quantitative PCR

Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2

Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeats

Clusters of transcription-coupled repair in the human genome.

ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress.

Replication of damaged DNA: molecular defect in xeroderma pigmentosum variant cells.

Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli.

Structure and variability of human chromosome ends

DNA repair of pyrimidine dimers and 6-4 photoproducts in the ribosomal DNA.

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scholarly article

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10.1371/JOURNAL.PGEN.1000926

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