Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeats - Wikidata - wikimedia - TriplyDB

Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeats

Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeats

http://www.wikidata.org/entity/Q24811877

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Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution Structure of the Human Telomere in K + Solution: A Stable Basket-Type G-Quadruplex with Only Two G-Tetrad Layers Sequence variant (CTAGGG)n in the human telomere favors a G-quadruplex structure containing a G{middle dot}C{middle dot}G{middle dot}C tetrad Human replication protein A unfolds telomeric G-quadruplexes Human replication protein A melts a DNA triple helix structure in a potent and specific manner Duplex formation at the 5' end affects the quadruplex conformation of the human telomeric repeat overhang in sodium but not in potassium.Assessing diversity of DNA structure-related sequence features in prokaryotic genomes Single molecule studies of physiologically relevant telomeric tails reveal POT1 mechanism for promoting G-quadruplex unfolding.Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair Telomeric repeat mutagenicity in human somatic cells is modulated by repeat orientation and G-quadruplex stability.Polycyclic azoniahetarenes: assessing the binding parameters of complexes between unsubstituted ligands and G-quadruplex DNA.How long is too long? Effects of loop size on G-quadruplex stability.Human Telomere G-Quadruplexes with Five Repeats Accommodate 8-Oxo-7,8-dihydroguanine by Looping out the DNA Damage.Different loop arrangements of intramolecular human telomeric (3+1) G-quadruplexes in K+ solution.Telomeric overhang length determines structural dynamics and accessibility to telomerase and ALT-associated proteins Investigation of spectral conversion of d(TTAGGG)4 and d(TTAGGG)13 upon potassium titration by a G-quadruplex recognizer BMVC molecule.Structure of the human telomere in K+ solution: an intramolecular (3 + 1) G-quadruplex scaffold Ion-dependent conformational switching by a DNA aptamer that induces remyelination in a mouse model of multiple sclerosis.X-ray characterization of mesophases of human telomeric G-quadruplexes and other DNA analogues.Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics.Polymorphism of human telomeric quadruplex structures Direct experimental evidence for quadruplex-quadruplex interaction within the human ILPR.Circular dichroism and conformational polymorphism of DNA.Stabilization of G-quadruplex in the BCL2 promoter region in double-stranded DNA by invading short PNAs.Intramolecular telomeric G-quadruplexes dramatically inhibit DNA synthesis by replicative and translesion polymerases, revealing their potential to lead to genetic change.DNA polymerase δ stalls on telomeric lagging strand templates independently from G-quadruplex formation.Human telomeric G-quadruplex: structures of DNA and RNA sequences.Effect of sequence and metal ions on UVB-induced anti cyclobutane pyrimidine dimer formation in human telomeric DNA sequences.Divalent cations and molecular crowding buffers stabilize G-triplex at physiologically relevant temperatures G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription.The effect of the TRF2 N-terminal and TRFH regions on telomeric G-quadruplex structures.Seven essential questions on G-quadruplexes.Molecular dynamics and principal components analysis of human telomeric quadruplex multimers.Evaluation of the interaction between long telomeric DNA and macrocyclic hexaoxazole (6OTD) dimer of a G-quadruplex ligand.Pt(II) squares as selective and effective human telomeric G-quadruplex binders and potential cancer therapeutics.Platinum squares with high selectivity and affinity for human telomeric G-quadruplexes.Hybrid ligand-alkylating agents targeting telomeric G-quadruplex structures.

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Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeats

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Nucleic Acids Research

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Guanine tetraplex topology of ...... the number of (TTAGGG) repeats

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Iva Kejnovská

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Jana Chládková

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Jaroslav Kypr

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Markéta Fialová

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Michaela Vorlícková

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P2860

Crystal structure of parallel quadruplexes from human telomeric DNA

Vertebrate telomere repeat DNAs favor external loop propeller quadruplex structures in the presence of high concentrations of potassium.

A thymine tetrad in d(TGGGGT) quadruplexes stabilized with Tl+/Na+ ions

The high-resolution crystal structure of a parallel-stranded guanine tetraplex

Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex

Solution structure of a parallel-stranded G-quadruplex DNA

In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei

Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kinetics

Structure and function of telomeres

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes

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scholarly article

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1081833

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10.1093/NAR/GKI898

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18

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33

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7544251

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16221978

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1253834

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