Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling - Wikidata - wikimedia - TriplyDB

Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling

Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling

http://www.wikidata.org/entity/Q33818886

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PKCdelta regulates cortical radial migration by stabilizing the Cdk5 activator p35 AKT and CDK5/p35 mediate brain-derived neurotrophic factor induction of DARPP-32 in medium size spiny neurons in vitro A Tale of the Good and Bad: Remodeling of the Microtubule Network in the Brain by Cdk5 Targeted Epigenetic Remodeling of the Cdk5 Gene in Nucleus Accumbens Regulates Cocaine- and Stress-Evoked Behavior The internal state of medium spiny neurons varies in response to different input signals DARPP-32 is a robust integrator of dopamine and glutamate signals Quantitative trait locus analysis identifies rat genomic regions related to amphetamine-induced locomotion and Galpha(i3) levels in nucleus accumbens.Suppression of neuroinflammation in forebrain-specific Cdk5 conditional knockout mice by PPARγ agonist improves neuronal loss and early lethality The 3' untranslated region of human Cyclin-Dependent Kinase 5 Regulatory subunit 1 contains regulatory elements affecting transcript stability Therapeutic targeting of "DARPP-32": a key signaling molecule in the dopiminergic pathway for the treatment of opiate addiction The role of miR-103 and miR-107 in regulation of CDK5R1 expression and in cellular migration.Cyclin-dependent kinase 5 activity regulates pain signaling.Protein kinases and addiction.Basolateral amygdala cdk5 activity mediates consolidation and reconsolidation of memories for cocaine cues.Resveratrol inhibits Cdk5 activity through regulation of p35 expression Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine.Regulation of ERK Kinase by MEK1 Kinase Inhibition in the Brain p35 and Rac1 underlie the neuroprotection and cognitive improvement induced by CDK5 silencing.Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies Transforming growth factor-β1 regulates Cdk5 activity in primary sensory neurons.Synaptic Plasticity and Signal Transduction Gene Polymorphisms and Vulnerability to Drug Addictions in Populations of European or African Ancestry.The "ups and downs" of signaling cascades in addiction.TRPV1 function is modulated by Cdk5-mediated phosphorylation: insights into the molecular mechanism of nociception Cyclin-dependent kinase 5 in synaptic plasticity, learning and memory.Targeted overexpression of tumor necrosis factor-α increases cyclin-dependent kinase 5 activity and TRPV1-dependent Ca2+ influx in trigeminal neurons TGF-β1 sensitizes TRPV1 through Cdk5 signaling in odontoblast-like cells.Tumor necrosis factor-alpha regulates cyclin-dependent kinase 5 activity during pain signaling through transcriptional activation of p35.Activation of cyclin-dependent kinase 5 mediates orofacial mechanical hyperalgesia.Cdk5: An Emerging Kinase in Pain Signaling Nanotherapeutic approach for opiate addiction using DARPP-32 gene silencing in an animal model of opiate addiction.Tale of the Good and the Bad Cdk5: Remodeling of the Actin Cytoskeleton in the Brain.Histone deacetylase 5 limits cocaine reward through cAMP-induced nuclear import.Dopamine signaling negatively regulates striatal phosphorylation of Cdk5 at tyrosine 15 in mice.Interaction of Cdk5 and cAMP/PKA Signaling in the Mediation of Neuropsychiatric and Neurodegenerative Diseases.Cdk5 Is Essential for Amphetamine to Increase Dendritic Spine Density in Hippocampal Pyramidal Neurons.Activation of Dopamine D1-D2 Receptor Complex Attenuates Cocaine Reward and Reinstatement of Cocaine-Seeking through Inhibition of DARPP-32, ERK, and ΔFosB.CDK5 in oncology: recent advances and future prospects.Neuronal nuclear organization is controlled by cyclin-dependent kinase 5 phosphorylation of Ras Guanine nucleotide releasing factor-1.Cdk5/p35 is required for motor coordination and cerebellar plasticity.Inducible Knockout of the Cyclin-Dependent Kinase 5 Activator p35 Alters Hippocampal Spatial Coding and Neuronal Excitability.

P2860

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P2860

Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling

http://www.wikidata.org/entity/Q33818886

description

2005 nî lūn-bûn

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2005 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2005 թվականի հունվարին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Increased activity of cyclin-d ...... ne-mediated dopamine signaling

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Increased activity of cyclin-d ...... ne-mediated dopamine signaling

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Increased activity of cyclin-d ...... ne-mediated dopamine signaling

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Increased activity of cyclin-d ...... ne-mediated dopamine signaling

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PNAS.0409456102

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Proceedings of the National Academy of Sciences of the United States of America

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Increased activity of cyclin-d ...... ne-mediated dopamine signaling

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P2093

Andrew Cho

http://www.w3.org/2001/XMLSchema#string

Ashok B Kulkarni

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Harish C Pant

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Michael J Iadarola

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Roscoe O Brady

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Satoru Takahashi

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Taduru Sreenath

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Toshio Ohshima

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Yong Kim

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P2860

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain

Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum

Molecular basis of long-term plasticity underlying addiction

Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine.

Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade.

Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine.

A decade of CDK5.

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1737-1742

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