Dynamic models of G-protein coupled receptor dimers: indications of asymmetry in the rhodopsin dimer from molecular dynamics simulations in a POPC bilayer.
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Principles and Overview of Sampling Methods for Modeling Macromolecular Structure and DynamicsRequirements and ontology for a G protein-coupled receptor oligomerization knowledge base.Monomeric G protein-coupled receptor rhodopsin in solution activates its G protein transducin at the diffusion limit.Structural and dynamic effects of cholesterol at preferred sites of interaction with rhodopsin identified from microsecond length molecular dynamics simulations.Modern homology modeling of G-protein coupled receptors: which structural template to use?Ligand-dependent conformations and dynamics of the serotonin 5-HT(2A) receptor determine its activation and membrane-driven oligomerization propertiesMethods used to study the oligomeric structure of G-protein-coupled receptors.Towards a quantitative representation of the cell signaling mechanisms of hallucinogens: measurement and mathematical modeling of 5-HT1A and 5-HT2A receptor-mediated ERK1/2 activationProgress in elucidating the structural and dynamic character of G Protein-Coupled Receptor oligomers for use in drug discovery.Changes in conformation at the cytoplasmic ends of the fifth and sixth transmembrane helices of a yeast G protein-coupled receptor in response to ligand binding.Mutations affecting the oligomerization interface of G-protein-coupled receptors revealed by a novel de novo protein design frameworkAsymmetry of the rhodopsin dimer in complex with transducinCoarse-grained modeling of allosteric regulation in protein receptorsAdvances in the Development and Application of Computational Methodologies for Structural Modeling of G-Protein Coupled Receptors.An Ensemble-Based Protocol for the Computational Prediction of Helix-Helix Interactions in G Protein-Coupled Receptors using Coarse-Grained Molecular DynamicsMulti-Component Protein - Protein Docking Based Protocol with External Scoring for Modeling Dimers of G Protein-Coupled Receptors.Computational Insights into the Mechanism of Inhibition of OASS-A by a Small Molecule Inhibitor.Understanding the molecular basis of agonist/antagonist mechanism of human mu opioid receptor through gaussian accelerated molecular dynamics method.Influence of oligomerization on the dynamics of G-protein coupled receptors as assessed by normal mode analysis.Toward an understanding of agonist binding to human Orexin-1 and Orexin-2 receptors with G-protein-coupled receptor modeling and site-directed mutagenesis.Active state-like conformational elements in the beta2-AR and a photoactivated intermediate of rhodopsin identified by dynamic properties of GPCRs.Membrane cholesterol effect on the 5-HT2A receptor: Insights into the lipid-induced modulation of an antipsychotic drug target.Molecular Dynamics Simulations of G Protein-Coupled Receptors.Understanding the effects on constitutive activation and drug binding of a D130N mutation in the β2 adrenergic receptor via molecular dynamics simulation.Light induced transmembrane proton gradient in artificial lipid vesicles reconstituted with photosynthetic reaction centers.
P2860
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P2860
Dynamic models of G-protein coupled receptor dimers: indications of asymmetry in the rhodopsin dimer from molecular dynamics simulations in a POPC bilayer.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Dynamic models of G-protein co ...... simulations in a POPC bilayer.
@ast
Dynamic models of G-protein co ...... simulations in a POPC bilayer.
@en
type
label
Dynamic models of G-protein co ...... simulations in a POPC bilayer.
@ast
Dynamic models of G-protein co ...... simulations in a POPC bilayer.
@en
prefLabel
Dynamic models of G-protein co ...... simulations in a POPC bilayer.
@ast
Dynamic models of G-protein co ...... simulations in a POPC bilayer.
@en
P2860
P1476
Dynamic models of G-protein co ...... simulations in a POPC bilayer
@en
P2093
Simon X Wang
P2860
P2888
P304
P356
10.1007/S10822-006-9053-3
P577
2006-07-01T00:00:00Z