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β-Adrenergic receptor subtype signaling in heart: from bench to bedside.

β-Adrenergic receptor subtype signaling in heart: from bench to bedside.

http://www.wikidata.org/entity/Q33828730

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G-protein Coupled Receptor Signaling in Pluripotent Stem Cell-derived Cardiovascular Cells: Implications for Disease Modeling Mechanisms of altered Ca²⁺ handling in heart failure Administration of a selective β2 adrenergic receptor antagonist exacerbates neuropathology and cognitive deficits in a mouse model of Alzheimer's disease Inhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytes Genetic determinants of arterial stiffness.PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-adrenergic signaling MECHANISMS UNDERLYING ACTION OF XINMAILONG INJECTION, A TRADITIONAL CHINESE MEDICINE IN CARDIAC FUNCTION IMPROVEMENT.Functional cross-talk between the α1- and β1-adrenergic receptors modulates the rapidly activating delayed rectifier potassium current in guinea pig ventricular myocytes.Cypher/ZASP is a novel A-kinase anchoring protein.Sex differences in β-adrenergic responsiveness of action potentials and intracellular calcium handling in isolated rabbit hearts Maternal diet-induced obesity programs cardiovascular dysfunction in adult male mouse offspring independent of current body weight β2 adrenergic receptor activation governs cardiac repolarization and arrhythmogenesis in a guinea pig model of heart failure Biased β2-adrenoceptor signalling in heart failure: pathophysiology and drug discovery.Advances in receptor conformation research: the quest for functionally selective conformations focusing on the β2-adrenoceptor Altered sarcoplasmic reticulum calcium cycling--targets for heart failure therapy.β-arrestin-biased signaling through the β2-adrenergic receptor promotes cardiomyocyte contraction.Adrenergic receptors and metabolism: role in development of cardiovascular disease Molecular interactions between fenoterol stereoisomers and derivatives and the β₂-adrenergic receptor binding site studied by docking and molecular dynamics simulations.Three basic residues of intracellular loop 3 of the beta-1 adrenergic receptor are required for golgin-160-dependent trafficking.Targeting cardiac β-adrenergic signaling via GRK2 inhibition for heart failure therapy Pharmacogenetics of cardiac inotropy.Myocardial glycogen dynamics: new perspectives on disease mechanisms.Ventricular action potential adaptation to regular exercise: role of β-adrenergic and KATP channel function.β-Blockers, Cocaine, and the Unopposed α-Stimulation Phenomenon.Inflammation and cardiac dysfunction during sepsis, muscular dystrophy, and myocarditis.Raf kinase inhibitor protein: lessons of a better way for β-adrenergic receptor activation in the heart.Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling.Prenatal exposure to β2-adrenoreceptor agonists and the risk of autism spectrum disorders in offspring.High concentration of epigallocatechin-3-gallate increased the incidences of arrhythmia and diastolic dysfunction via β2-adrenoceptor.Activation of β-adrenergic receptor promotes cellular proliferation in human glioblastoma.Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the β2-adrenoceptor.PDE2 activity differs in right and left rat ventricular myocardium and differentially regulates β2 adrenoceptor-mediated effects.Skeletal Muscle-specific G Protein-coupled Receptor Kinase 2 Ablation Alters Isolated Skeletal Muscle Mechanics and Enhances Clenbuterol-stimulated Hypertrophy.A new era for GPCR research: structures, biology and drug discovery.Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress.Gαi is required for carvedilol-induced β1 adrenergic receptor β-arrestin biased signaling.Investigating β-adrenergic-induced cardiac hypertrophy through computational approach: classical and non-classical pathways.Functional β2-adrenoceptors in rat left atria: effect of foot-shock stress.Role of cyclic AMP sensor Epac1 in masseter muscle hypertrophy and myosin heavy chain transition induced by β2-adrenoceptor stimulation.Left ventricular remodelling in chronic primary mitral regurgitation: implications for medical therapy.

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P2860

β-Adrenergic receptor subtype signaling in heart: from bench to bedside.

http://www.wikidata.org/entity/Q33828730

description

2012 nî lūn-bûn

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2012 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2012 թվականի հունվարին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

β-Adrenergic receptor subtype signaling in heart: from bench to bedside.

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β-Adrenergic receptor subtype signaling in heart: from bench to bedside.

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β-Adrenergic receptor subtype signaling in heart: from bench to bedside.

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β-Adrenergic receptor subtype signaling in heart: from bench to bedside.

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β-Adrenergic receptor subtype signaling in heart: from bench to bedside.

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Acta Pharmacologica Sinica

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β-Adrenergic receptor subtype signaling in heart: from bench to bedside.

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Anthony Yiu Ho Woo

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Rui-ping Xiao

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P2860

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

Beta-adrenoceptor stimulation potentiates insulin-stimulated PKB phosphorylation in rat cardiomyocytes via cAMP and PKA

Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice

Preservation of myocardial beta-adrenergic receptor signaling delays the development of heart failure after myocardial infarction

Beta 1- and beta 2-adrenergic receptor-mediated adenylate cyclase stimulation in nonfailing and failing human ventricular myocardium

How many drug targets are there?

G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization

Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF)

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor

Dual modulation of cell survival and cell death by beta(2)-adrenergic signaling in adult mouse cardiac myocytes

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335-341

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scholarly article

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10.1038/APS.2011.201

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3

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33

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2012-01-30T00:00:00Z

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221788554

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1026586925

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