Dual modulation of cell survival and cell death by beta(2)-adrenergic signaling in adult mouse cardiac myocytes
about
Ser/ Thr residues at α3/β5 loop of Gαs are important in morphine-induced adenylyl cyclase sensitization but not mitogen-activated protein kinase phosphorylationBeta-adrenoceptor stimulation potentiates insulin-stimulated PKB phosphorylation in rat cardiomyocytes via cAMP and PKAGIPC interacts with the beta1-adrenergic receptor and regulates beta1-adrenergic receptor-mediated ERK activationProtein kinase A-mediated phosphorylation of the beta 2-adrenergic receptor regulates its coupling to Gs and Gi. Demonstration in a reconstituted systemStress-mediated increases in systemic and local epinephrine impair skin wound healing: potential new indication for beta blockersMyocardial MiR-30 downregulation triggered by doxorubicin drives alterations in β-adrenergic signaling and enhances apoptosisRGS2 is a primary terminator of β₂-adrenergic receptor-mediated G(i) signalingAgonist-specific activation of the beta2-adrenoceptor/Gs-protein and beta2-adrenoceptor/Gi-protein pathway in adult rat ventricular cardiomyocytes.G-protein beta subunit of Cochliobolus heterostrophus involved in virulence, asexual and sexual reproductive ability, and morphogenesis.T-tubule remodelling disturbs localized β2-adrenergic signalling in rat ventricular myocytes during the progression of heart failure.Cardioprotection specific for the G protein Gi2 in chronic adrenergic signaling through beta 2-adrenoceptors.β-Adrenergic receptor subtype signaling in heart: from bench to bedside.The effects and possible mechanism of β2AR gene expression in cardiocytes of canines with heart failureβ-Adrenergic receptor-PI3K signaling crosstalk in mouse heart: elucidation of immediate downstream signaling cascades.{beta}1-Adrenergic receptor activation induces mouse cardiac myocyte death through both L-type calcium channel-dependent and -independent pathways.Beta(2)-adrenoceptor agonist clenbuterol reduces infarct size and myocardial apoptosis after myocardial ischaemia/reperfusion in anaesthetized ratsAkt induces enhanced myocardial contractility and cell size in vivo in transgenic mice.Level of G protein-coupled receptor kinase-2 determines myocardial ischemia/reperfusion injury via pro- and anti-apoptotic mechanisms.Impact of combined clenbuterol and metoprolol therapy on reverse remodelling during mechanical unloading.Functional selectivity in adrenergic and angiotensin signaling systems.Beta-adrenergic signaling in the heart: dual coupling of the beta2-adrenergic receptor to G(s) and G(i) proteins.Adrenergic regulation of cardiac myocyte apoptosis.Total beta-adrenoceptor knockout slows conduction and reduces inducible arrhythmias in the mouse heart.Cardiac T-Tubule Microanatomy and Function.β₂ AR agonists in treatment of chronic heart failure: long path to translation.Myocardial oxidative stress contributes to transgenic β₂-adrenoceptor activation-induced cardiomyopathy and heart failure.Autonomic control of blood pressure in mice: basic physiology and effects of genetic modification.Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling.Increased beta2-adrenoceptors in doxorubicin-induced cardiomyopathy in rat.The switching role of β-adrenergic receptor signalling in cell survival or death decision of cardiomyocytes.Linkage of beta1-adrenergic stimulation to apoptotic heart cell death through protein kinase A-independent activation of Ca2+/calmodulin kinase II.β2 adrenergic receptor activation governs cardiac repolarization and arrhythmogenesis in a guinea pig model of heart failureReceptor crosstalk. Implications for cardiovascular function, disease and therapy.Heart protection by combination therapy with esmolol and milrinone at late-ischemia and early reperfusion.Cardiovascular pharmacogenomics of adrenergic receptor signaling: clinical implications and future directionsTargeting the inflammasome and adenosine type-3 receptors improves outcome of antibiotic therapy in murine anthraxTargeting signaling pathways in heart failure by gene transfer.Multiple signalling pathways involved in beta2-adrenoceptor-mediated glucose uptake in rat skeletal muscle cells.THE ROLE OF β-ADRENERGIC RECEPTORS IN HEART FAILURE: DIFFERENTIAL REGULATION OF CARDIOTOXICITY AND CARDIOPROTECTION.Differential cardiotoxic/cardioprotective effects of beta-adrenergic receptor subtypes in myocytes and fibroblasts in doxorubicin cardiomyopathy.
P2860
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P2860
Dual modulation of cell survival and cell death by beta(2)-adrenergic signaling in adult mouse cardiac myocytes
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Dual modulation of cell surviv ...... n adult mouse cardiac myocytes
@ast
Dual modulation of cell surviv ...... n adult mouse cardiac myocytes
@en
type
label
Dual modulation of cell surviv ...... n adult mouse cardiac myocytes
@ast
Dual modulation of cell surviv ...... n adult mouse cardiac myocytes
@en
prefLabel
Dual modulation of cell surviv ...... n adult mouse cardiac myocytes
@ast
Dual modulation of cell surviv ...... n adult mouse cardiac myocytes
@en
P2093
P2860
P356
P1476
Dual modulation of cell surviv ...... n adult mouse cardiac myocytes
@en
P2093
P2860
P304
P356
10.1073/PNAS.98.4.1607
P407
P577
2001-02-01T00:00:00Z