Biochemistry of visual pigment regeneration: the Friedenwald lecture.
about
Disease-associated variants of microsomal retinol dehydrogenase 12 (RDH12) are degraded at mutant-specific ratesNewfoundland rod-cone dystrophy, an early-onset retinal dystrophy, is caused by splice-junction mutations in RLBP1Rod and cone visual pigments and phototransduction through pharmacological, genetic, and physiological approachesThe many different cellular functions of MYO7A in the retinaRPE65, visual cycle retinol isomerase, is not inherently 11-cis-specific: support for a carbocation mechanism of retinol isomerizationLocalizations of visual cycle components in retinal pigment epitheliumThe Usher 1B protein, MYO7A, is required for normal localization and function of the visual retinoid cycle enzyme, RPE65The Full Globin Repertoire of Turtles Provides Insights into Vertebrate Globin Evolution and FunctionsRelease of 11-cis-retinal from cellular retinaldehyde-binding protein by acidic lipids.Shedding light on photoperiodismNon-invasive bleaching of the human lens by femtosecond laser photolysis.Phagocytosis of retinal rod and cone photoreceptors.Relationships among visual cycle retinoids, rhodopsin phosphorylation, and phototransduction in mouse eyes during light and dark adaptation.Interaction of extracellular domain 2 of the human retina-specific ATP-binding cassette transporter (ABCA4) with all-trans-retinalImpacts of hypoxia-inducible factor-1 knockout in the retinal pigment epithelium on choroidal neovascularization.Rescue and repair during photoreceptor cell renewal mediated by docosahexaenoic acid-derived neuroprotectin D1.Recovery of rod photoresponses in ABCR-deficient mice.Lecithin retinol acyltransferase forms functional homodimers.Defective lipid transport and biosynthesis in recessive and dominant Stargardt macular degenerationReduction of all-trans retinal to all-trans retinol in the outer segments of frog and mouse rod photoreceptorsA cleavable affinity biotinylating agent reveals a retinoid binding role for RPE65Delayed dark adaptation in 11-cis-retinol dehydrogenase-deficient mice: a role of RDH11 in visual processes in vivo.Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver.Human cone visual pigment deletions spare sufficient photoreceptors to warrant gene therapyRapid formation of all-trans retinol after bleaching in frog and mouse rod photoreceptor outer segments.Altered expression of retinal molecular markers in the canine RPE65 model of Leber congenital amaurosisGeneration of Cre transgenic mice with postnatal RPE-specific ocular expressionThe mammalian cone visual cycle promotes rapid M/L-cone pigment regeneration independently of the interphotoreceptor retinoid-binding protein.Rod outer segment retinol formation is independent of Abca4, arrestin, rhodopsin kinase, and rhodopsin palmitylationRetinal dystrophy resulting from ablation of RXR alpha in the mouse retinal pigment epitheliumInterphotoreceptor retinoid-binding protein protects retinoids from photodegradationCiliary ectosomes: transmissions from the cell's antenna.All-trans retinol in rod photoreceptor outer segments moves unrestrictedly by passive diffusionImprovement in vision: a new goal for treatment of hereditary retinal degenerationsReduction of all-trans-retinal in vertebrate rod photoreceptors requires the combined action of RDH8 and RDH12.Aromatic residues in the substrate cleft of RPE65 protein govern retinol isomerization and modulate its progression.Determination of N-retinylidene-N-retinylethanolamine (A2E) levels in central and peripheral areas of human retinal pigment epitheliumSafety assessment in macaques of light exposures for functional two-photon ophthalmoscopy in humans.Xanthophylls are preferentially taken up compared with beta-carotene by retinal cells via a SRBI-dependent mechanismCellular retinol binding protein 1 modulates photoreceptor outer segment folding in the isolated eye.
P2860
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P2860
Biochemistry of visual pigment regeneration: the Friedenwald lecture.
description
2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2000 թվականի փետրվարին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Biochemistry of visual pigment regeneration: the Friedenwald lecture.
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Biochemistry of visual pigment regeneration: the Friedenwald lecture.
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type
label
Biochemistry of visual pigment regeneration: the Friedenwald lecture.
@ast
Biochemistry of visual pigment regeneration: the Friedenwald lecture.
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prefLabel
Biochemistry of visual pigment regeneration: the Friedenwald lecture.
@ast
Biochemistry of visual pigment regeneration: the Friedenwald lecture.
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P1476
Biochemistry of visual pigment regeneration: the Friedenwald lecture
@en
P2093
P304
P407
P577
2000-02-01T00:00:00Z