A murine early thymocyte developmental sequence is marked by transient expression of the interleukin 2 receptor
about
Point mutations at the purine nucleoside phosphorylase locus impair thymocyte differentiation in the mouseMetabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ culturesImpairment of T cell development in deltaEF1 mutant miceDevelopment of CD4+CD8+ thymocytes in RAG-deficient mice through a T cell receptor beta chain-independent pathwayDetailed analysis of gene expression during development of T cell lineages in the thymus.A novel TCR transgenic model reveals that negative selection involves an immediate, Bim-dependent pathway and a delayed, Bim-independent pathway.The GTPase Rho has a critical regulatory role in thymus development.Intrathymic administration of hematopoietic progenitor cells enhances T cell reconstitution in ZAP-70 severe combined immunodeficiency.TCR beta and TCR alpha gene enhancers confer tissue- and stage-specificity on V(D)J recombination events.Revision of T cell receptor {alpha} chain genes is required for normal T lymphocyte development.Trafficking from the bone marrow to the thymus: a prerequisite for thymopoiesis.Primitive lymphoid progenitors in bone marrow with T lineage reconstituting potential.Genes, pathways and checkpoints in lymphocyte development and homeostasis.A cell cycle analysis of growth-related genes expressed during T lymphocyte maturation.The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cells.Lineage relationships and developmental kinetics of immature thymocytes: CD3, CD4, and CD8 acquisition in vivo and in vitroRegulation of thymocyte development through CD3. I. Timepoint of ligation of CD3 epsilon determines clonal deletion or induction of developmental program.Phenotypic and functional analysis of positive selection in the gamma/delta T cell lineageFc gamma RII/III and CD2 expression mark distinct subpopulations of immature CD4-CD8- murine thymocytes: in vivo developmental kinetics and T cell receptor beta chain rearrangement status.Two waves of recombinase gene expression in developing thymocytes.Temporal and lineage-specific control of T cell receptor alpha/delta gene rearrangement by T cell receptor alpha and delta enhancers.Thymic dendritic cell precursors: relationship to the T lymphocyte lineage and phenotype of the dendritic cell progeny.Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development.Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros.Developmental regulation of VDJ recombination by the core fragment of the T cell receptor alpha enhancerT cell receptor (TCR)-beta gene recombination: dissociation from cell cycle regulation and developmental progression during T cell ontogeny.From stem cell to T cell: one route or many?Journey through the thymus: stromal guides for T-cell development and selection.Abnormal deletions in the T-cell receptor delta locus of mouse thymocytes.Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilon.Adoptive precursor cell therapy to enhance immune reconstitution after hematopoietic stem cell transplantation in mouse and man.An enhancer-blocking element between alpha and delta gene segments within the human T cell receptor alpha/delta locusComplete TCR-α gene locus control region activity in T cells derived in vitro from embryonic stem cellsA delta T-cell receptor deleting element transgenic reporter construct is rearranged in alpha beta but not gamma delta T-cell lineagesA potential role for Elf-1 in terminal transferase gene regulationIkaros induces quiescence and T-cell differentiation in a leukemia cell line.Extrathymic pathways of T-cell differentiation in the liver and other organs.Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene.Regulation of thymocyte development through CD3. II. Expression of T cell receptor beta CD3 epsilon and maturation to the CD4+8+ stage are highly correlated in individual thymocytesThe expression of several T cell-specific and novel genes is repressed by trans-acting factors in immature T lymphoma clones.
P2860
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P2860
A murine early thymocyte developmental sequence is marked by transient expression of the interleukin 2 receptor
description
1989 nî lūn-bûn
@nan
1989 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի մարտին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
A murine early thymocyte devel ...... of the interleukin 2 receptor
@ast
A murine early thymocyte devel ...... of the interleukin 2 receptor
@en
type
label
A murine early thymocyte devel ...... of the interleukin 2 receptor
@ast
A murine early thymocyte devel ...... of the interleukin 2 receptor
@en
prefLabel
A murine early thymocyte devel ...... of the interleukin 2 receptor
@ast
A murine early thymocyte devel ...... of the interleukin 2 receptor
@en
P2093
P2860
P356
P1476
A murine early thymocyte devel ...... of the interleukin 2 receptor
@en
P2093
P2860
P304
P356
10.1073/PNAS.86.5.1614
P407
P577
1989-03-01T00:00:00Z