Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene.
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A THEMIS:SHP1 complex promotes T-cell survivalA conserved CXXC motif in CD3epsilon is critical for T cell development and TCR signalingProteomic Signatures of ThymomasMetabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ culturesCD3 delta deficiency arrests development of the alpha beta but not the gamma delta T cell lineage.Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell developmentActivation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with ageQuantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hubCD3 and immunoglobulin G Fc receptor regulate cerebellar functions.Targeted in vitro and in vivo gene transfer into T lymphocytes: potential of direct inhibition of allo-immune activationIL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism.Organization of proximal signal initiation at the TCR:CD3 complex.High incidence of proviral integrations in the Hoxa locus in a new model of E2a-PBX1-induced B-cell leukemia.Constitutively oxidized CXXC motifs within the CD3 heterodimeric ectodomains of the T cell receptor complex enforce the conformation of juxtaposed segments.ITAM-mediated signaling by the T-cell antigen receptorModeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes.Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody.The CD3gamma chain is essential for development of both the TCRalphabeta and TCRgammadelta lineages.T cells contribute to tumor progression by favoring pro-tumoral properties of intra-tumoral myeloid cells in a mouse model for spontaneous melanoma.The requirement for pre-TCR during thymic differentiation enforces a developmental pause that is essential for V-DJβ rearrangement.Naive T cells proliferate strongly in neonatal mice in response to self-peptide/self-MHC complexes.Distinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alpha beta T cell receptors.Cellular inhibitor of apoptosis proteins prevent clearance of hepatitis B virus.Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORgamma t and LTi cells.CD81 interacts with the T cell receptor to suppress signalingFacilitation of beta selection and modification of positive selection in the thymus of PD-1-deficient miceSCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cellsOn the role of MHC class II molecules in the survival and lymphopenia-induced proliferation of peripheral CD4+ T cells.Hoxb4 overexpression in CD4 memory phenotype T cells increases the central memory population upon homeostatic proliferationPerturbation of thymocyte development in nonsense-mediated decay (NMD)-deficient mice.Enhancer control of V(D)J recombination at the TCRbeta locus: differential effects on DNA cleavage and joining.γδ T cells confer protection against murine cytomegalovirus (MCMV).Dendritic Cells Cause Bone Lesions in a New Mouse Model of HistiocytosisT-B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3zeta subunit of the T-cell antigen receptor complex.Acute Liver Injury Is Independent of B Cells or Immunoglobulin M.Exacerbation of experimental autoimmune encephalomyelitis in prion protein (PrPc)-null mice: evidence for a critical role of the central nervous systemDominant Role of CD80-CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LAT(Y136F) CD4(+) T CellsSpontaneous retrotransposon insertion into TNF 3'UTR causes heart valve disease and chronic polyarthritis.Characterization of Thymic Settling Progenitors in the Mouse Embryo Using In Vivo and In Vitro Assaysp16INK4A tumor suppressor gene expression and CD3epsilon deficiency but not pre-TCR deficiency inhibit TAL1-linked T-lineage leukemogenesis.
P2860
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P2860
Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene.
description
1995 nî lūn-bûn
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1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
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1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
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1995年學術文章
@zh-hant
name
Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene.
@en
type
label
Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene.
@en
prefLabel
Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene.
@en
P2093
P2860
P1433
P1476
Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene.
@en
P2093
Malissen B
Malissen M
P2860
P304
P407
P577
1995-10-01T00:00:00Z