Evidence for the progressive and adaptive nature of spontaneous transformation in the NIH 3T3 cell line.
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Neoplastic development: paradoxical relation between impaired cell growth at low population density and excessive growth at high densityCell-cycle arrest in TrkA-expressing NIH3T3 cells involves nitric oxide synthase.Degrees and kinds of selection in spontaneous neoplastic transformation: an operational analysisPhysiological induction and reversal of focus formation and tumorigenicity in NIH 3T3 cells.Necdin, a p53-target gene, is an inhibitor of p53-mediated growth arrest.Heritable, population-wide damage to cells as the driving force of neoplastic transformation.Synergistic mechanisms in carcinogenesis by polycyclic aromatic hydrocarbons and by tobacco smoke: a bio-historical perspective with updates.Selective clonal expansion and microenvironmental permissiveness in tobacco carcinogenesis.Cellular epigenetics: topochronology of progressive "spontaneous" transformation of cells under growth constraint.Selective nature of phorbol 12-myristate 13-acetate-induced neoplastic transformation in NIH 3T3 cells.Occurrence and control of sporadic proliferation in growth arrested Swiss 3T3 feeder cells.Experimental control of neoplastic progression in cell populations: Foulds' rules revisited.A critical test of the role of population density in producing transformation.Clonal dynamics of progressive neoplastic transformationSelective killing of preneoplastic and neoplastic cells by methotrexate with leucovorinCell-cell contact interactions conditionally determine suppression and selection of the neoplastic phenotype.Automatic enumeration and characterization of heterogeneous clonal progression in cell transformation.Cellular epigenetics: effects of passage history on competence of cells for "spontaneous" transformation.Adaptive evolution of degrees and kinds of neoplastic transformation in cell culturePromotion and selection by serum growth factors drive field cancerization, which is anticipated in vivo by type 2 diabetes and obesityCoculturing diverse clonal populations prevents the early-stage neoplastic progression that occurs in the separate clonesSensitivity of transformation to small differences in population density during serial passage of NIH 3T3 cells.The cellular ecology of progressive neoplastic transformation: a clonal analysis.Cellular epigenetics: control of the size, shape, and spatial distribution of transformed foci by interactions between the transformed and nontransformed cells.Growth in high serum concentrations leads to rapid deadaptation of cells previously adapted to growth in an extremely low concentration of serum.Relation of spontaneous transformation in cell culture to adaptive growth and clonal heterogeneity.Cellular aging, destabilization, and cancer.Cooperation of simian virus 40 large and small T antigens in metabolic stabilization of tumor suppressor p53 during cellular transformation.Analogues of Y27632 increase gap junction communication and suppress the formation of transformed NIH3T3 coloniesStabilization of the tumor suppressor p53 during cellular transformation by simian virus 40: influence of viral and cellular factors and biological consequences.Liver cells can spontaneously resume proliferation in long-term quiescent primary cultures.Will we cure cancer by sequencing thousands of genomes?Dynamics of cell transformation in culture and its significance for tumor development in animals.An optimization protocol for Swiss 3T3 feeder cell growth-arrest by Mitomycin C dose-to-volume derivation strategy.Phenotypic selection as the biological mode of epigenetic conversion and reversion in cell transformation.
P2860
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P2860
Evidence for the progressive and adaptive nature of spontaneous transformation in the NIH 3T3 cell line.
description
1989 nî lūn-bûn
@nan
1989 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի մարտին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Evidence for the progressive a ...... tion in the NIH 3T3 cell line.
@ast
Evidence for the progressive a ...... tion in the NIH 3T3 cell line.
@en
type
label
Evidence for the progressive a ...... tion in the NIH 3T3 cell line.
@ast
Evidence for the progressive a ...... tion in the NIH 3T3 cell line.
@en
prefLabel
Evidence for the progressive a ...... tion in the NIH 3T3 cell line.
@ast
Evidence for the progressive a ...... tion in the NIH 3T3 cell line.
@en
P2860
P356
P1476
Evidence for the progressive a ...... tion in the NIH 3T3 cell line.
@en
P2860
P304
P356
10.1073/PNAS.86.6.1860
P407
P577
1989-03-01T00:00:00Z