Anticancer efficacy of a difluorodiarylidenyl piperidone (HO-3867) in human ovarian cancer cells and tumor xenografts.
about
Safe and targeted anticancer efficacy of a novel class of antioxidant-conjugated difluorodiarylidenyl piperidones: differential cytotoxicity in healthy and cancer cellsInduction of ATM/ATR pathway combined with Vγ2Vδ2 T cells enhances cytotoxicity of ovarian cancer cellsBiomarker robustness reveals the PDGF network as driving disease outcome in ovarian cancer patients in multiple studies.HO-3867, a synthetic compound, inhibits the migration and invasion of ovarian carcinoma cells through downregulation of fatty acid synthase and focal adhesion kinase.Cellular uptake, retention and bioabsorption of HO-3867, a fluorinated curcumin analog with potential antitumor properties.Aberrantly activated pSTAT3-Ser727 in human endometrial cancer is suppressed by HO-3867, a novel STAT3 inhibitor.Potential application of curcumin and its analogues in the treatment strategy of patients with primary epithelial ovarian cancer.HO-3867, a safe STAT3 inhibitor, is selectively cytotoxic to ovarian cancer.A novel curcumin analog (H-4073) enhances the therapeutic efficacy of cisplatin treatment in head and neck cancerAmelioration of doxorubicin-induced cardiotoxicity by an anticancer-antioxidant dual-function compound, HO-3867USP-11 as a predictive and prognostic factor following neoadjuvant therapy in women with breast cancerSafe and targeted anticancer therapy for ovarian cancer using a novel class of curcumin analogsPulmonary hypertension secondary to left-heart failure involves peroxynitrite-induced downregulation of PTEN in the lung.Early responses of the STAT3 pathway to platinum drugs are associated with cisplatin resistance in epithelial ovarian cancer.Low-Dose DMC Significantly Enhances the Effect of TMZ on Glioma Cells by Targeting Multiple Signaling Pathways Both In Vivo and In Vitro.Synthesis of 4-methyl-N'-(3-alkyl-2r,6c-diarylpiperidin-4-ylidene)-1,2,3-thiadiazole-5-carbohydrazides with antioxidant, antitumor and antimicrobial activities.HO-3867, a STAT3 inhibitor induces apoptosis by inactivation of STAT3 activity in BRCA1-mutated ovarian cancer cells.Cell growth inhibition and induction of apoptosis by snake venom toxin in ovarian cancer cell via inactivation of nuclear factor κB and signal transducer and activator of transcription 3.The Curcumin Analogue 1,5-Bis(2-hydroxyphenyl)-1,4-pentadiene-3-one Induces Apoptosis and Downregulates E6 and E7 Oncogene Expression in HPV16 and HPV18-Infected Cervical Cancer Cells.Anticancer potential of diarylidenyl piperidone derivatives, HO-4200 and H-4318, in cisplatin resistant primary ovarian cancer.Elevated STAT3 expression in ovarian cancer ascites promotes invasion and metastasis: a potential therapeutic target.Targeting STAT3 by HO3867 induces apoptosis in ovarian clear cell carcinoma.The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53.Anti-apoptotic effect of interleukin-22 on fibroblast-like synoviocytes in patients with rheumatoid arthritis is mediated via the signal transducer and activator of transcription 3 signaling pathway.
P2860
Q33762105-D0EE7732-1ADC-44CD-AD08-C7407466BAEAQ33849537-F1B7F33C-0873-4750-97E9-13B3FE247315Q34124475-EC0CE2F1-218F-4B3A-A5A7-D395C2F7548BQ34139276-407BD7E0-6433-4063-9A76-2BC5320989CCQ34616583-3CE58D23-8105-4C74-94BA-EEE2826C6E4DQ34819689-F42D368B-D3D6-4704-998B-476CFDB3ADAFQ34833628-6B0978C4-BB74-4B06-9601-08FD9FBE0D77Q34855872-015FCFE1-F5D9-4C3E-B0F7-1E203A9F95ECQ35133375-5E4765B4-065D-41D1-A1EF-1DADABBD3490Q35429931-9C8339AF-A761-49B2-96CE-4DE4BAB2E86EQ36599308-99A7FF53-3221-4C03-900E-D873DC109D04Q36880907-4C4F6881-4839-431C-B5B5-0DC443655405Q37105620-FC9C2368-500B-440C-BA52-8918F20EF885Q37371530-277F6026-D870-4344-849B-623D13C4DC19Q38828567-4F6E45DB-7C06-45BD-B0E4-F2C75F4B9B86Q38978886-BA19AA21-D2DE-4454-8176-AF1D7D74C3ECQ39313548-A5BAA401-1AA2-4E18-9149-C8E74928C202Q39340284-F6C3FA22-3B85-42EF-8BDE-6019E0D3A580Q40777873-16B1342F-01A7-4655-86DF-225A5965D27CQ41573533-A7AB4C2D-8F45-49A1-83CD-E55B62AA890AQ41863613-504B70AC-7D10-4B6C-BB09-29C8A6D737B4Q48227188-1C062067-A19B-4D1F-9F9D-82937E0FD33EQ49571721-111AEBA0-9058-4CFF-AE94-768CAA41A8D0Q53056147-5A8ABA25-CE01-401C-9DB8-4CEF8B757FB4
P2860
Anticancer efficacy of a difluorodiarylidenyl piperidone (HO-3867) in human ovarian cancer cells and tumor xenografts.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Anticancer efficacy of a diflu ...... er cells and tumor xenografts.
@ast
Anticancer efficacy of a diflu ...... er cells and tumor xenografts.
@en
type
label
Anticancer efficacy of a diflu ...... er cells and tumor xenografts.
@ast
Anticancer efficacy of a diflu ...... er cells and tumor xenografts.
@en
prefLabel
Anticancer efficacy of a diflu ...... er cells and tumor xenografts.
@ast
Anticancer efficacy of a diflu ...... er cells and tumor xenografts.
@en
P2093
P2860
P1476
Anticancer efficacy of a diflu ...... er cells and tumor xenografts.
@en
P2093
Anna Bratasz
Brian K Rivera
Karuppaiyah Selvendiran
Kálmán Hideg
Liyue Tong
M Lakshmi Kuppusamy
Nancy J Trigg
Periannan Kuppusamy
Shabnam Ahmed
Tamás Kálai
P2860
P304
P356
10.1158/1535-7163.MCT-09-1207
P577
2010-05-04T00:00:00Z