Amelioration of doxorubicin-induced cardiotoxicity by an anticancer-antioxidant dual-function compound, HO-3867 - Wikidata - wikimedia - TriplyDB

Amelioration of doxorubicin-induced cardiotoxicity by an anticancer-antioxidant dual-function compound, HO-3867

Amelioration of doxorubicin-induced cardiotoxicity by an anticancer-antioxidant dual-function compound, HO-3867

http://www.wikidata.org/entity/Q35429931

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Cardioprotective Potentials of Plant-Derived Small Molecules against Doxorubicin Associated Cardiotoxicity The tell-tale heart: molecular and cellular responses to childhood anthracycline exposure Doxorubicin combined with celecoxib inhibits tumor growth of medullary thyroid carcinoma in xenografted mice Withaferin A synergizes the therapeutic effect of doxorubicin through ROS-mediated autophagy in ovarian cancer Aberrantly activated pSTAT3-Ser727 in human endometrial cancer is suppressed by HO-3867, a novel STAT3 inhibitor.HO-3867, a safe STAT3 inhibitor, is selectively cytotoxic to ovarian cancer.Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells.Pulmonary hypertension secondary to left-heart failure involves peroxynitrite-induced downregulation of PTEN in the lung.Sulfated polysaccharide-protein complex sensitizes doxorubicin-induced apoptosis of breast cancer cells in vitro and in vivo.Anticancer potential of diarylidenyl piperidone derivatives, HO-4200 and H-4318, in cisplatin resistant primary ovarian cancer.Cardioprotective effects of curcumin and nebivolol against doxorubicin-induced cardiac toxicity in rats.

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Amelioration of doxorubicin-induced cardiotoxicity by an anticancer-antioxidant dual-function compound, HO-3867

http://www.wikidata.org/entity/Q35429931

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2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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JPET.111.183681

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Journal of Pharmacology and Experimental Therapeutics

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Amelioration of doxorubicin-in ...... ual-function compound, HO-3867

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Alex Dayton

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Karuppaiyah Selvendiran

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Kálmán Hideg

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M Lakshmi Kuppusamy

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Periannan Kuppusamy

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Sarath Meduru

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Shan Naidu

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Tamás Kálai

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P2860

Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity

Targeting multidrug resistance in cancer

Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1).

Safe and targeted anticancer efficacy of a novel class of antioxidant-conjugated difluorodiarylidenyl piperidones: differential cytotoxicity in healthy and cancer cells

Anticancer efficacy of a difluorodiarylidenyl piperidone (HO-3867) in human ovarian cancer cells and tumor xenografts.

Cardiotoxicity of doxorubicin and other anthracycline derivatives.

HO-3867, a synthetic compound, inhibits the migration and invasion of ovarian carcinoma cells through downregulation of fatty acid synthase and focal adhesion kinase.

Protection against oxidative stress by nitroxides.

Potent induction of cellular antioxidants and phase 2 enzymes by resveratrol in cardiomyocytes: protection against oxidative and electrophilic injury.

Doxorubicin-induced apoptosis: implications in cardiotoxicity.

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