PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms.
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The role of poly(ADP-ribosyl)ation in DNA damage response and cancer chemotherapyRepair of persistent strand breaks in the mitochondrial genomeStructures of the Human Poly (ADP-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by ADP-HPD DerivativesStructure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding elementThe structural basis of XRCC1-mediated DNA repairADP-ribosyl-acceptor hydrolase 3 regulates poly (ADP-ribose) degradation and cell death during oxidative stressMolecular Insights into Poly(ADP-ribose) Recognition and Processing.PARG is dispensable for recovery from transient replicative stress but required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress.Kinetics of endogenous mouse FEN1 in base excision repair.Selenoprotein H suppresses cellular senescence through genome maintenance and redox regulationPoly(ADP-ribosyl) glycohydrolase prevents the accumulation of unusual replication structures during unperturbed S phaseMicro-irradiation tools to visualize base excision repair and single-strand break repairRing finger protein 146/Iduna is a poly(ADP-ribose) polymer binding and PARsylation dependent E3 ubiquitin ligase.The impact of cyclin-dependent kinase 5 depletion on poly(ADP-ribose) polymerase activity and responses to radiationThe Replication Checkpoint Prevents Two Types of Fork Collapse without Regulating Replisome Stability.Herpes simplex virus 1 infection activates poly(ADP-ribose) polymerase and triggers the degradation of poly(ADP-ribose) glycohydrolase.Is there an epigenetic component underlying the resistance of triple-negative breast cancers to parp inhibitors?PARG dysfunction enhances DNA double strand break formation in S-phase after alkylation DNA damage and augments different cell death pathways.Effects of poly (ADP-ribosyl) polymerase (PARP) inhibitor on cisplatin resistance & proliferation of the ovarian cancer C13* cellsStrategic Combination of DNA-Damaging Agent and PARP Inhibitor Results in Enhanced CytotoxicityPoly(ADP-ribose) polymerases covalently modify strand break termini in DNA fragments in vitro.Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses.Structural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling.The recognition and removal of cellular poly(ADP-ribose) signals.PARP-2 depletion results in lower radiation cell survival but cell line-specific differences in poly(ADP-ribose) levels.Knockout of PARG110 confers resistance to cGMP-induced toxicity in mammalian photoreceptorsDiscovery of a selective allosteric inhibitor targeting macrodomain 2 of poly-adenosine-diphosphate-ribose polymerases 14.PARP inhibitors protect against sex- and AAG-dependent alkylation-induced neural degeneration.Meta-analysis of DNA double-strand break response kinetics.Genomic and transcriptomic heterogeneity in metaplastic carcinomas of the breast.The role of poly ADP-ribosylation in the first wave of DNA damage response.A novel non-canonical PIP-box mediates PARG interaction with PCNA.PARG dePARylates PARP1;PARP2Maneuvers on PCNA Rings during DNA Replication and RepairThe Importance of Poly(ADP-Ribose) Polymerase as a Sensor of Unligated Okazaki Fragments during DNA Replication
P2860
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P2860
PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms.
description
2011 nî lūn-bûn
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2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
PARG is recruited to DNA damag ...... and PCNA-dependent mechanisms.
@ast
PARG is recruited to DNA damag ...... and PCNA-dependent mechanisms.
@en
type
label
PARG is recruited to DNA damag ...... and PCNA-dependent mechanisms.
@ast
PARG is recruited to DNA damag ...... and PCNA-dependent mechanisms.
@en
prefLabel
PARG is recruited to DNA damag ...... and PCNA-dependent mechanisms.
@ast
PARG is recruited to DNA damag ...... and PCNA-dependent mechanisms.
@en
P2093
P2860
P356
P1476
PARG is recruited to DNA damag ...... and PCNA-dependent mechanisms
@en
P2093
Heinrich Leonhardt
Jean-Christophe Amé
Oliver Mortusewicz
Valérie Schreiber
P2860
P304
P356
10.1093/NAR/GKR099
P407
P577
2011-03-11T00:00:00Z