Involvement of the proteasome in various degradative processes in mammalian cells.
about
UBC1 encodes a novel member of an essential subfamily of yeast ubiquitin-conjugating enzymes involved in protein degradation.Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins.Demonstration that a human 26S proteolytic complex consists of a proteasome and multiple associated protein components and hydrolyzes ATP and ubiquitin-ligated proteins by closely linked mechanismsCloning and sequence analysis of a cDNA clone from Arabidopsis thaliana homologous to a proteasome alpha subunit from Drosophila.Expansion of the mycobacterial "PUPylome"Abnormally high expression of proteasomes in human leukemic cells.Phosphorylation of the 19S regulatory particle ATPase subunit, Rpt6, modifies susceptibility to proteotoxic stress and protein aggregation.The 'second-codon rule' and autophosphorylation govern the stability and activity of Mos during the meiotic cell cycle in Xenopus oocytes.Novel natural peptide substrates for endopeptidase 24.15, neurolysin, and angiotensin-converting enzyme.ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to ubiquitinRegulation by proteolysis: energy-dependent proteases and their targets.Nucleotide sequence of PUP1 encoding a putative proteasome subunit in Saccharomyces cerevisiae.Proteasome inhibitor (MG-132) treatment of mdx mice rescues the expression and membrane localization of dystrophin and dystrophin-associated proteinsHigh-molecular-mass multicatalytic proteinase complexes produced by the nitrogen-fixing actinomycete Frankia strain BR.ATP-dependent degradation of a mutant serine: pyruvate/alanine:glyoxylate aminotransferase in a primary hyperoxaluria type 1 caseBortezomib: a valuable new antineoplastic strategy in multiple myeloma.Initiation of cyclin B degradation by the 26S proteasome upon egg activation.The ubiquitin-mediated system for intracellular protein degradation.Heat shock and oxygen radicals stimulate ubiquitin-dependent degradation mainly of newly synthesized proteins.An ATP-stabilized inhibitor of the proteasome is a component of the 1500-kDa ubiquitin conjugate-degrading complexProteasome beta subunit pharmacogenomics: gene resequencing and functional genomics.Proteasome inhibition enhances antitumour effects of gemcitabine in experimental pancreatic cancer.Possible mechanism of nuclear translocation of proteasomes.High molecular mass intracellular proteases.The male-specific factor Sry harbors an oncogenic function.Changes in protein profiles of multiple myeloma cells in response to bortezomib.Proteasomes: multicatalytic proteinase complexesInhibition of 20 S and 26 S proteasome activity by lithium chloride: impact on the differentiation of leukemia cells by all-trans retinoic acid.The ubiquitin-mediated proteolytic pathway.The 26S proteasome degrades mouse and yeast ornithine decarboxylase in yeast cells.Biochemistry and pathology of radical-mediated protein oxidation.The 20S proteasome mediates the degradation of mouse and yeast ornithine decarboxylase in yeast cells.In vivo function of the proteasome in the ubiquitin pathway.Comparative resistance of the 20S and 26S proteasome to oxidative stress.Molecular interaction of the proteasome (multicatalytic proteinase). Evidence that the proteasome is not a constituent of the '26 S' multienzyme complex.Purification of a protease in red blood cells that degrades oxidatively damaged haemoglobin.Transient nuclear factor kappaB (NF-kappaB) activation stimulated by interleukin-1beta may be partly dependent on proteasome activity, but not phosphorylation and ubiquitination of the IkappaBalpha molecule, in C6 glioma cells. Regulation of NF-kappCloning and sequence analysis of pituitary cDNA encoding the beta-subunit of Xenopus proteasome.Development of Small Molecular Proteasome Inhibitors Using a Caenorhabditis elegans Screen.Hijacking of the Ubiquitin/Proteasome Pathway by the HIV Auxiliary Proteins.
P2860
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P2860
Involvement of the proteasome in various degradative processes in mammalian cells.
description
1989 nî lūn-bûn
@nan
1989 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Involvement of the proteasome in various degradative processes in mammalian cells.
@ast
Involvement of the proteasome in various degradative processes in mammalian cells.
@en
type
label
Involvement of the proteasome in various degradative processes in mammalian cells.
@ast
Involvement of the proteasome in various degradative processes in mammalian cells.
@en
prefLabel
Involvement of the proteasome in various degradative processes in mammalian cells.
@ast
Involvement of the proteasome in various degradative processes in mammalian cells.
@en
P2093
P2860
P356
P1476
Involvement of the proteasome in various degradative processes in mammalian cells
@en
P2093
A Ichihara
A L Goldberg
W Matthews
P2860
P304
P356
10.1073/PNAS.86.8.2597
P407
P577
1989-04-01T00:00:00Z