C --> T mutagenesis and gamma-radiation sensitivity due to deficiency in the Smug1 and Ung DNA glycosylases
about
SMUG1 is able to excise uracil from immunoglobulin genes: insight into mutation versus repairHuman APOBEC3G can restrict retroviral infection in avian cells and acts independently of both UNG and SMUG1Uracil-DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanismsThe current state of eukaryotic DNA base damage and repairDNA glycosylases: in DNA repair and beyondUracil DNA N-glycosylase promotes assembly of human centromere protein ARetinal degeneration and ionizing radiation hypersensitivity in a mouse model for Cockayne syndromeRegulatory mechanisms of RNA function: emerging roles of DNA repair enzymes.Direct interaction between XRCC1 and UNG2 facilitates rapid repair of uracil in DNA by XRCC1 complexes.Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice.Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy.Uracil in DNA and its processing by different DNA glycosylasesDehydration, deamination and enzymatic repair of cytosine glycols from oxidized poly(dG-dC) and poly(dI-dC)Phylogenomic analysis of the uracil-DNA glycosylase superfamilyGenomic uracil homeostasis during normal B cell maturation and loss of this balance during B cell cancer development.DNA polymerase delta-dependent repair of DNA single strand breaks containing 3'-end proximal lesions.Ectopic restriction of DNA repair reveals that UNG2 excises AID-induced uracils predominantly or exclusively during G1 phaseAssociation of the DNA repair SMUG1 rs3087404 polymorphism and its interaction with high sensitivity C-reactive protein for age-related macular degeneration in Iranian patients.Folate and colorectal cancer in rodents: a model of DNA repair deficiency.Genetic variability in DNA repair proteins in age-related macular degeneration.The very 5' end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regionsOxidative DNA damage repair in mammalian cells: a new perspective.Base excision repair, aging and health span.Folate deficiency induces genomic uracil misincorporation and hypomethylation but does not increase DNA point mutations.Uracil within DNA: an actor of antiviral immunity.Small interfering RNA-directed knockdown of uracil DNA glycosylase induces apoptosis and sensitizes human prostate cancer cells to genotoxic stress.Mutational spectrum at GATA1 provides insights into mutagenesis and leukemogenesis in Down syndrome.DNA base repair--recognition and initiation of catalysis.Vpr expression abolishes the capacity of HIV-1 infected cells to repair uracilated DNA.My journey to DNA repair.Mechanisms underlying mutational signatures in human cancers.Abrogation of the CLK-2 checkpoint leads to tolerance to base-excision repair intermediates.MicroRNA-31 modulates tumour sensitivity to radiation in oesophageal adenocarcinoma.Heat shock protein 70 enhanced deoxyribonucleic acid base excision repair in human leukemic cells after ionizing radiation.Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1.Specialization of an Exonuclease III family enzyme in the repair of 3' DNA lesions during base excision repair in the human pathogen Neisseria meningitidis.Non-coding cancer driver candidates identified with a sample- and position-specific model of the somatic mutation rate.Formation of isodialuric acid lesion within DNA oligomers via one-electron oxidation of 5-hydroxyuracil: characterization, stability and excision repairMutational effects of γ-rays and carbon ion beams on Arabidopsis seedlings.A comparative study of uracil-DNA glycosylases from human and herpes simplex virus type 1.
P2860
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P2860
C --> T mutagenesis and gamma-radiation sensitivity due to deficiency in the Smug1 and Ung DNA glycosylases
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
C --> T mutagenesis and gamma- ...... Smug1 and Ung DNA glycosylases
@ast
C --> T mutagenesis and gamma- ...... Smug1 and Ung DNA glycosylases
@en
type
label
C --> T mutagenesis and gamma- ...... Smug1 and Ung DNA glycosylases
@ast
C --> T mutagenesis and gamma- ...... Smug1 and Ung DNA glycosylases
@en
prefLabel
C --> T mutagenesis and gamma- ...... Smug1 and Ung DNA glycosylases
@ast
C --> T mutagenesis and gamma- ...... Smug1 and Ung DNA glycosylases
@en
P2093
P2860
P356
P1433
P1476
C --> T mutagenesis and gamma- ...... Smug1 and Ung DNA glycosylases
@en
P2093
Deborah E Barnes
Peter Robins
P2860
P304
P356
10.1038/SJ.EMBOJ.7600689
P407
P577
2005-05-19T00:00:00Z