Distinct roles of the three Akt isoforms in lactogenic differentiation and involution. - Wikidata - wikimedia - TriplyDB

Distinct roles of the three Akt isoforms in lactogenic differentiation and involution.

Distinct roles of the three Akt isoforms in lactogenic differentiation and involution.

http://www.wikidata.org/entity/Q33854404

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Mammary gland development Exploring the gain of function contribution of AKT to mammary tumorigenesis in mouse models.Novel transcripts from a distinct promoter that encode the full-length AKT1 in human breast cancer cells Stat5 promotes survival of mammary epithelial cells through transcriptional activation of a distinct promoter in Akt1.Key signalling nodes in mammary gland development and cancer. Signalling downstream of PI3 kinase in mammary epithelium: a play in 3 Akts.Akt1 is essential for postnatal mammary gland development, function, and the expression of Btn1a1.Akt1 and akt2 play distinct roles in the initiation and metastatic phases of mammary tumor progression Genetically engineered mouse models of PI3K signaling in breast cancer.Regulation of facilitative glucose transporters and AKT/MAPK/PRKAA signaling via estradiol and progesterone in the mouse uterine epithelium Akt is required for Stat5 activation and mammary differentiation.Decreased IGF type 1 receptor signaling in mammary epithelium during pregnancy leads to reduced proliferation, alveolar differentiation, and expression of insulin receptor substrate (IRS)-1 and IRS-2.Signal transducer and activator of transcription 5 as a key signaling pathway in normal mammary gland developmental biology and breast cancer.Effects of glucose on lactose synthesis in mammary epithelial cells from dairy cow Eph receptor and ephrin function in breast, gut, and skin epithelia.Impaired mouse mammary gland growth and development is mediated by melatonin and its MT1G protein-coupled receptor via repression of ERα, Akt1, and Stat5 ZnT4 (SLC30A4)-null ("lethal milk") mice have defects in mammary gland secretion and hallmarks of precocious involution during lactation Hunk negatively regulates c-myc to promote Akt-mediated cell survival and mammary tumorigenesis induced by loss of Pten.Mammary involution and breast cancer risk: transgenic models and clinical studies.AKT3 controls mitochondrial biogenesis and autophagy via regulation of the major nuclear export protein CRM-1.Akt1 and insulin-like growth factor 2 (Igf2) regulate placentation and fetal/postnatal development.Current perspectives on Akt Akt-ivation and Akt-ions.Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis.Cancer stem cell-like phenotype and survival are coordinately regulated by Akt/FoxO/Bim pathway.Metabolic Transition of Milk Lactose Synthesis and Up-regulation by AKT1 in Sows from Late Pregnancy to Lactation.PI3K/AKT pathway regulates phosphorylation of steroid receptors, hormone independence and tumor differentiation in breast cancer.ErbB3 drives mammary epithelial survival and differentiation during pregnancy and lactation.The contribution of adhesion signaling to lactogenesis.Making milk: A new link between STAT5 and Akt1 The functional effects and mechanisms by which fibroblast growth factor 2 (FGF2) controls bovine mammary epithelial cells: Implications for the development and functionality of the bovine mammary gland.Adiponectin: A prosurvival and proproliferation signal that increases bovine mammary epithelial cell numbers and protects them from endoplasmic reticulum stress responses.Regulation of Mammary Luminal Cell Fate and Tumorigenesis by p38α.Bifunctional role of ephrin A1-Eph system in stimulating cell proliferation and protecting cells from cell death through the attenuation of ER stress and inflammatory responses in bovine mammary epithelial cells.Role of Akt Isoforms Controlling Cancer Stem Cell Survival, Phenotype and Self-Renewal.WIP-YAP/TAZ as A New Pro-Oncogenic Pathway in Glioma.

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P2860

Distinct roles of the three Akt isoforms in lactogenic differentiation and involution.

http://www.wikidata.org/entity/Q33854404

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2008 nî lūn-bûn

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2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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name

Distinct roles of the three Akt isoforms in lactogenic differentiation and involution.

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Distinct roles of the three Akt isoforms in lactogenic differentiation and involution.

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type

label

Distinct roles of the three Akt isoforms in lactogenic differentiation and involution.

@ast

Distinct roles of the three Akt isoforms in lactogenic differentiation and involution.

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prefLabel

Distinct roles of the three Akt isoforms in lactogenic differentiation and involution.

@ast

Distinct roles of the three Akt isoforms in lactogenic differentiation and involution.

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P1476

Distinct roles of the three Akt isoforms in lactogenic differentiation and involution.

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P2093

Charlotte Kuperwasser

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Ina Klebba

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Ioanna G Maroulakou

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Philip N Tsichlis

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Stephen P Naber

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William Oemler

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P2860

AKT/PKB signaling: navigating downstream

Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta

Life with a single isoform of Akt: mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficiencies

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development

Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland

Lactation and a reduced risk of premenopausal breast cancer

Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

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468-477

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10.1002/JCP.21518

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2

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