Stat5 promotes survival of mammary epithelial cells through transcriptional activation of a distinct promoter in Akt1.
about
Low levels of Stat5a protein in breast cancer are associated with tumor progression and unfavorable clinical outcomesMammary gland developmentD-type Cyclins are important downstream effectors of cytokine signaling that regulate the proliferation of normal and neoplastic mammary epithelial cells.Mapping the zinc-transporting system in mammary cells: molecular analysis reveals a phenotype-dependent zinc-transporting network during lactationUrsolic acid-mediated apoptosis of K562 cells involves Stat5/Akt pathway inhibition through the induction of Gfi-1Integrative Analysis of Transcriptomic and Epigenomic Data to Reveal Regulation Patterns for BMD Variation.Novel transcripts from a distinct promoter that encode the full-length AKT1 in human breast cancer cellsExpression of STAT5, COX-2 and PIAS3 in correlation with NSCLC histhopathological features.Generation of a novel MMTV-tTA transgenic mouse strain for the targeted expression of genes in the embryonic and postnatal mammary glandLeptin induces cyclin D1 expression and proliferation of human nucleus pulposus cells via JAK/STAT, PI3K/Akt and MEK/ERK pathways.Prolactin receptor is a negative prognostic factor in patients with squamous cell carcinoma of the head and neck.The transcription factors signal transducer and activator of transcription 5A (STAT5A) and STAT5B negatively regulate cell proliferation through the activation of cyclin-dependent kinase inhibitor 2b (Cdkn2b) and Cdkn1a expressionSignal transducer and activator of transcription 5a/b: biomarker and therapeutic target in prostate and breast cancerCyclin D3 compensates for the loss of cyclin D1 during ErbB2-induced mammary tumor initiation and progression.Signal transducer and activator of transcription 5 as a key signaling pathway in normal mammary gland developmental biology and breast cancer.The two faces of Janus kinases and their respective STATs in mammary gland development and cancerImpaired mouse mammary gland growth and development is mediated by melatonin and its MT1G protein-coupled receptor via repression of ERα, Akt1, and Stat5The BH3-only protein BIM contributes to late-stage involution in the mouse mammary gland.Forced involution of the functionally differentiated mammary gland by overexpression of the pro-apoptotic protein baxSTAT signaling in mammary gland differentiation, cell survival and tumorigenesisStat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis.Molecular regulators of pubertal mammary gland development.Crosstalk between STAT5 activation and PI3K/AKT functions in normal and transformed mammary epithelial cells.STAT5 deletion in macrophages alters ductal elongation and branching during mammary gland development.Orphan nuclear receptor NR4A2 induces transcription of the immunomodulatory peptide hormone prolactin.Aberrantly high expression of the CUB and zona pellucida-like domain-containing protein 1 (CUZD1) in mammary epithelium leads to breast tumorigenesis.Expression of the mRNA stability regulator Tristetraprolin is required for lactation maintenance in the mouse mammary gland.Role of STAT5 and epigenetics in lactation-associated upregulation of multidrug transporter ABCG2 in the mammary gland.
P2860
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P2860
Stat5 promotes survival of mammary epithelial cells through transcriptional activation of a distinct promoter in Akt1.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Stat5 promotes survival of mam ...... f a distinct promoter in Akt1.
@ast
Stat5 promotes survival of mam ...... f a distinct promoter in Akt1.
@en
type
label
Stat5 promotes survival of mam ...... f a distinct promoter in Akt1.
@ast
Stat5 promotes survival of mam ...... f a distinct promoter in Akt1.
@en
prefLabel
Stat5 promotes survival of mam ...... f a distinct promoter in Akt1.
@ast
Stat5 promotes survival of mam ...... f a distinct promoter in Akt1.
@en
P2093
P2860
P356
P1476
Stat5 promotes survival of mam ...... of a distinct promoter in Akt1
@en
P2093
Aleata A Triplett
Bradley A Creamer
Jeffrey W Schmidt
Kazuhito Sakamoto
P2860
P304
P356
10.1128/MCB.00851-09
P407
P577
2010-04-12T00:00:00Z